CATH Superfamily 2.70.170.10
Neurotransmitter-gated ion-channel ligand-binding domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Neurotransmitter-gated ion-channel ligand-binding domain
".
FunFam 2: Glycine receptor alpha 1 subunit
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 25 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Extracellularly glycine-gated chloride channel activity GO:0016934
Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
|
27 |
F1Q832 (/IDA)
F1QJA0 (/IDA)
F1RDZ6 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
(17 more) |
Extracellularly glycine-gated ion channel activity GO:0016933
Enables the transmembrane transfer of an ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
|
21 |
A0A2R8Q3D5 (/IDA)
A0A2R8Q5V1 (/IDA)
A0A2R8Q8T1 (/IDA)
A0A2R8QBE2 (/IDA)
A0A2R8QMY9 (/IDA)
B3DJL8 (/IDA)
D1KZ66 (/IDA)
F1Q832 (/IDA)
F1Q835 (/IDA)
F1QCW4 (/IDA)
(11 more) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
20 |
A0A2R8Q3D5 (/IDA)
A0A2R8Q5V1 (/IDA)
A0A2R8Q8T1 (/IDA)
A0A2R8QBE2 (/IDA)
A0A2R8QMY9 (/IDA)
B3DJL8 (/IDA)
D1KZ66 (/IDA)
F1Q832 (/IDA)
F1Q835 (/IDA)
F1QCW4 (/IDA)
(10 more) |
Glycine-gated chloride ion channel activity GO:0022852
Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts.
|
12 |
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
(2 more) |
Glycine binding GO:0016594
Interacting selectively and non-covalently with glycine, aminoethanoic acid.
|
9 | O93430 (/IDA) O93430 (/IDA) P07727 (/IDA) P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) P23416 (/IDA) Q64018 (/IDA) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
5 | O93430 (/ISS) O93430 (/ISS) P07727 (/ISS) P57695 (/ISS) Q64018 (/ISS) |
Extracellularly glycine-gated chloride channel activity GO:0016934
Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
|
5 | P23415 (/IMP) P23415 (/IMP) P23415 (/IMP) P23415 (/IMP) Q64018 (/IMP) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | P23415 (/IPI) P23415 (/IPI) P23415 (/IPI) P23415 (/IPI) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
4 | P23415 (/IMP) P23415 (/IMP) P23415 (/IMP) P23415 (/IMP) |
Extracellularly glycine-gated chloride channel activity GO:0016934
Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
|
4 | Q64018 (/ISO) Q7TNC8 (/ISO) Q7TNC8 (/ISO) Q91XP5 (/ISO) |
Taurine binding GO:0030977
Interacting selectively and non-covalently with taurine.
|
4 | P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) |
Glycine binding GO:0016594
Interacting selectively and non-covalently with glycine, aminoethanoic acid.
|
3 | Q64018 (/ISO) Q7TNC8 (/ISO) Q7TNC8 (/ISO) |
Glycine binding GO:0016594
Interacting selectively and non-covalently with glycine, aminoethanoic acid.
|
3 | P07727 (/ISS) P57695 (/ISS) Q64018 (/ISS) |
Extracellularly glycine-gated chloride channel activity GO:0016934
Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
|
3 | P07727 (/ISS) P57695 (/ISS) Q64018 (/ISS) |
Glycine-gated chloride ion channel activity GO:0022852
Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts.
|
3 | Q7TNC8 (/ISO) Q7TNC8 (/ISO) Q91XP5 (/ISO) |
Taurine binding GO:0030977
Interacting selectively and non-covalently with taurine.
|
3 | P07727 (/ISS) P57695 (/ISS) Q64018 (/ISS) |
Transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:1904315
Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.
|
3 | Q64018 (/IDA) Q7TNC8 (/IDA) Q7TNC8 (/IDA) |
Transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:1904315
Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.
|
3 | Q64018 (/IMP) Q7TNC8 (/IMP) Q7TNC8 (/IMP) |
Glycine-gated chloride ion channel activity GO:0022852
Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts.
|
2 | P24524 (/ISS) Q91XP5 (/ISS) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q64018 (/ISO) |
Glycine binding GO:0016594
Interacting selectively and non-covalently with glycine, aminoethanoic acid.
|
1 | Q64018 (/IMP) |
Extracellularly glycine-gated ion channel activity GO:0016933
Enables the transmembrane transfer of an ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
|
1 | Q64018 (/ISO) |
Extracellularly glycine-gated chloride channel activity GO:0016934
Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
|
1 | P22771 (/TAS) |
Taurine binding GO:0030977
Interacting selectively and non-covalently with taurine.
|
1 | Q64018 (/ISO) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q64018 (/ISO) |
There are 72 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Chloride transmembrane transport GO:1902476
The process in which chloride is transported across a membrane.
|
18 |
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
(8 more) |
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
|
16 |
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
(6 more) |
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
14 |
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
(4 more) |
Startle response GO:0001964
An action or movement due to the application of a sudden unexpected stimulus.
|
10 | F1Q832 (/IMP) F1QJA0 (/IMP) F1RDZ6 (/IMP) P23415 (/IMP) P23415 (/IMP) P23415 (/IMP) P23415 (/IMP) Q5CZW5 (/IMP) Q64018 (/IMP) Q9DES9 (/IMP) |
Chloride transport GO:0006821
The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
10 | F1Q832 (/IDA) F1QJA0 (/IDA) F1RDZ6 (/IDA) P07727 (/IDA) P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) Q5CZW5 (/IDA) Q9DES9 (/IDA) |
Response to amino acid GO:0043200
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
|
8 | F1Q832 (/IDA) F1QJA0 (/IDA) F1RDZ6 (/IDA) O93430 (/IDA) O93430 (/IDA) Q5CZW5 (/IDA) Q61603 (/IDA) Q9DES9 (/IDA) |
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
|
7 | F1Q832 (/IMP) F1QJA0 (/IMP) F1RDZ6 (/IMP) O93430 (/IMP) O93430 (/IMP) Q5CZW5 (/IMP) Q9DES9 (/IMP) |
Regulation of neuron differentiation GO:0045664
Any process that modulates the frequency, rate or extent of neuron differentiation.
|
7 | F1Q832 (/IMP) F1QJA0 (/IMP) F1RDZ6 (/IMP) O93430 (/IMP) O93430 (/IMP) Q5CZW5 (/IMP) Q9DES9 (/IMP) |
Ion transport GO:0006811
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
6 | O93430 (/IDA) O93430 (/IDA) P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) |
Inhibitory postsynaptic potential GO:0060080
A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
|
6 | P07727 (/ISS) P23415 (/ISS) P23415 (/ISS) P23415 (/ISS) P23415 (/ISS) P57695 (/ISS) |
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
|
6 | P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) P23416 (/IDA) P24524 (/IDA) |
Cellular response to zinc ion GO:0071294
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
|
6 | P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) P23416 (/IDA) P24524 (/IDA) |
Cellular response to ethanol GO:0071361
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
|
6 | P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) P23416 (/IDA) P24524 (/IDA) |
Response to alcohol GO:0097305
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.
|
6 | P07727 (/ISS) P23415 (/ISS) P23415 (/ISS) P23415 (/ISS) P23415 (/ISS) P57695 (/ISS) |
Thigmotaxis GO:0001966
The directed movement of a motile cell or organism in response to touch.
|
5 | F1Q832 (/IMP) F1QJA0 (/IMP) F1RDZ6 (/IMP) Q5CZW5 (/IMP) Q9DES9 (/IMP) |
Neuropeptide signaling pathway GO:0007218
The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor.
|
5 | P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) P23416 (/IDA) |
Regulation of membrane potential GO:0042391
Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
|
5 | P23415 (/IMP) P23415 (/IMP) P23415 (/IMP) P23415 (/IMP) Q64018 (/IMP) |
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
|
5 | F1Q832 (/IGI) F1QJA0 (/IGI) F1RDZ6 (/IGI) Q5CZW5 (/IGI) Q9DES9 (/IGI) |
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
|
5 | F1Q832 (/IMP) F1QJA0 (/IMP) F1RDZ6 (/IMP) Q5CZW5 (/IMP) Q9DES9 (/IMP) |
Synaptic transmission, glycinergic GO:0060012
The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
|
5 | P23415 (/ISS) P23415 (/ISS) P23415 (/ISS) P23415 (/ISS) P57695 (/ISS) |
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
|
5 | O93430 (/ISS) O93430 (/ISS) P07727 (/ISS) P57695 (/ISS) Q64018 (/ISS) |
Cellular response to zinc ion GO:0071294
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
|
5 | O93430 (/ISS) O93430 (/ISS) P07727 (/ISS) P57695 (/ISS) Q64018 (/ISS) |
Cellular response to ethanol GO:0071361
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
|
5 | O93430 (/ISS) O93430 (/ISS) P07727 (/ISS) P57695 (/ISS) Q64018 (/ISS) |
Muscle contraction GO:0006936
A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
|
4 | P23415 (/IMP) P23415 (/IMP) P23415 (/IMP) P23415 (/IMP) |
Negative regulation of transmission of nerve impulse GO:0051970
Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
|
4 | P23415 (/IMP) P23415 (/IMP) P23415 (/IMP) P23415 (/IMP) |
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
|
4 | Q64018 (/ISO) Q7TNC8 (/ISO) Q7TNC8 (/ISO) Q91XP5 (/ISO) |
Cellular response to zinc ion GO:0071294
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
|
4 | Q64018 (/ISO) Q7TNC8 (/ISO) Q7TNC8 (/ISO) Q91XP5 (/ISO) |
Cellular response to ethanol GO:0071361
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
|
4 | Q64018 (/ISO) Q7TNC8 (/ISO) Q7TNC8 (/ISO) Q91XP5 (/ISO) |
Chloride transmembrane transport GO:1902476
The process in which chloride is transported across a membrane.
|
4 | Q64018 (/ISO) Q7TNC8 (/ISO) Q7TNC8 (/ISO) Q91XP5 (/ISO) |
Positive regulation of acrosome reaction GO:2000344
Any process that activates or increases the frequency, rate or extent of the acrosome reaction.
|
4 | P23415 (/IMP) P23415 (/IMP) P23415 (/IMP) P23415 (/IMP) |
Startle response GO:0001964
An action or movement due to the application of a sudden unexpected stimulus.
|
3 | P07727 (/ISS) P57695 (/ISS) Q64018 (/ISS) |
Ion transport GO:0006811
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | P07727 (/ISS) P57695 (/ISS) Q64018 (/ISS) |
Chloride transport GO:0006821
The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | P07727 (/ISS) P57695 (/ISS) Q64018 (/ISS) |
Muscle contraction GO:0006936
A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
|
3 | P07727 (/ISS) P57695 (/ISS) Q64018 (/ISS) |
Neuropeptide signaling pathway GO:0007218
The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor.
|
3 | Q64018 (/ISO) Q7TNC8 (/ISO) Q7TNC8 (/ISO) |
Neuropeptide signaling pathway GO:0007218
The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor.
|
3 | P07727 (/ISS) P57695 (/ISS) Q64018 (/ISS) |
Negative regulation of transmission of nerve impulse GO:0051970
Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
|
3 | P07727 (/ISS) P57695 (/ISS) Q64018 (/ISS) |
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
2 | Q7TNC8 (/ISO) Q7TNC8 (/ISO) |
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
2 | Q64018 (/ISO) Q91XP5 (/ISO) |
Action potential GO:0001508
A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.
|
1 | Q64018 (/IMP) |
Startle response GO:0001964
An action or movement due to the application of a sudden unexpected stimulus.
|
1 | Q64018 (/ISO) |
Regulation of respiratory gaseous exchange by nervous system process GO:0002087
A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates.
|
1 | Q64018 (/IMP) |
Ion transport GO:0006811
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q64018 (/ISO) |
Anion transport GO:0006820
The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | P07727 (/IDA) |
Anion transport GO:0006820
The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q64018 (/ISO) |
Chloride transport GO:0006821
The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q64018 (/ISO) |
Muscle contraction GO:0006936
A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
|
1 | Q64018 (/ISO) |
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
|
1 | Q64018 (/IMP) |
Acrosome reaction GO:0007340
The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida.
|
1 | Q64018 (/IMP) |
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
|
1 | P22771 (/IEP) |
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
|
1 | Q64018 (/IMP) |
Adult walking behavior GO:0007628
The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg.
|
1 | Q64018 (/IMP) |
Spinal cord development GO:0021510
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
|
1 | P22771 (/IEP) |
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
1 | P23416 (/IDA) |
Regulation of membrane potential GO:0042391
Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
|
1 | Q64018 (/IDA) |
Regulation of membrane potential GO:0042391
Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
|
1 | Q64018 (/ISO) |
Regulation of respiratory gaseous exchange GO:0043576
Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment.
|
1 | Q64018 (/IMP) |
Neuromuscular process controlling posture GO:0050884
Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.
|
1 | Q64018 (/IMP) |
Neuromuscular process GO:0050905
Any process pertaining to the functions of the nervous and muscular systems of an organism.
|
1 | Q64018 (/IMP) |
Protein heterooligomerization GO:0051291
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
1 | P07727 (/IDA) |
Protein heterooligomerization GO:0051291
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
1 | Q64018 (/ISO) |
Negative regulation of transmission of nerve impulse GO:0051970
Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
|
1 | Q64018 (/ISO) |
Synaptic transmission, glycinergic GO:0060012
The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
|
1 | P07727 (/IDA) |
Synaptic transmission, glycinergic GO:0060012
The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
|
1 | Q64018 (/IMP) |
Synaptic transmission, glycinergic GO:0060012
The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
|
1 | Q64018 (/ISO) |
Righting reflex GO:0060013
A reflex process in which an animal immediately tries to turn over after being placed in a supine position.
|
1 | Q64018 (/IMP) |
Inhibitory postsynaptic potential GO:0060080
A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
|
1 | Q64018 (/IMP) |
Response to alcohol GO:0097305
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.
|
1 | Q64018 (/IMP) |
Chloride transmembrane transport GO:1902476
The process in which chloride is transported across a membrane.
|
1 | Q91XP5 (/ISS) |
Regulation of synaptic vesicle exocytosis GO:2000300
Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
|
1 | Q91XP5 (/IDA) |
Regulation of synaptic vesicle exocytosis GO:2000300
Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
|
1 | Q91XP5 (/IMP) |
Positive regulation of acrosome reaction GO:2000344
Any process that activates or increases the frequency, rate or extent of the acrosome reaction.
|
1 | Q64018 (/ISO) |
There are 33 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
18 |
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
(8 more) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
16 |
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
O75311 (/TAS)
(6 more) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
15 |
O75311 (/IMP)
O75311 (/IMP)
O75311 (/IMP)
O75311 (/IMP)
O75311 (/IMP)
O75311 (/IMP)
O75311 (/IMP)
O75311 (/IMP)
O75311 (/IMP)
O75311 (/IMP)
(5 more) |
Glycine-gated chloride channel complex GO:0016935
A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts.
|
11 |
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
O75311 (/IDA)
(1 more) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
7 | O93430 (/ISS) O93430 (/ISS) P07727 (/ISS) P24524 (/ISS) P57695 (/ISS) Q64018 (/ISS) Q91XP5 (/ISS) |
Glycinergic synapse GO:0098690
A synapse that uses glycine as a neurotransmitter.
|
7 | P07727 (/IDA) P24524 (/IDA) Q61603 (/IDA) Q64018 (/IDA) Q7TNC8 (/IDA) Q7TNC8 (/IDA) Q91XP5 (/IDA) |
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
6 | P07727 (/ISS) P23415 (/ISS) P23415 (/ISS) P23415 (/ISS) P23415 (/ISS) P57695 (/ISS) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
6 | P07727 (/ISS) P23415 (/ISS) P23415 (/ISS) P23415 (/ISS) P23415 (/ISS) P57695 (/ISS) |
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
|
6 | P07727 (/ISS) P23415 (/ISS) P23415 (/ISS) P23415 (/ISS) P23415 (/ISS) P57695 (/ISS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
4 | Q64018 (/ISO) Q7TNC8 (/ISO) Q7TNC8 (/ISO) Q91XP5 (/ISO) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
4 | P23415 (/NAS) P23415 (/NAS) P23415 (/NAS) P23415 (/NAS) |
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
4 | P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) P23415 (/IDA) |
Glycinergic synapse GO:0098690
A synapse that uses glycine as a neurotransmitter.
|
4 | Q64018 (/IMP) Q7TNC8 (/IMP) Q7TNC8 (/IMP) Q91XP5 (/IMP) |
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
3 | P07727 (/ISS) P57695 (/ISS) Q64018 (/ISS) |
Integral component of postsynaptic specialization membrane GO:0099060
The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | P07727 (/IDA) P24524 (/IDA) Q61603 (/IDA) |
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
2 | P07727 (/IDA) Q64018 (/IDA) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | P07727 (/IDA) Q64018 (/IDA) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | O93430 (/IDA) O93430 (/IDA) |
Glycine-gated chloride channel complex GO:0016935
A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts.
|
2 | P24524 (/ISS) Q91XP5 (/ISS) |
Glycinergic synapse GO:0098690
A synapse that uses glycine as a neurotransmitter.
|
2 | Q64018 (/ISO) Q91XP5 (/ISO) |
Integral component of postsynaptic specialization membrane GO:0099060
The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q64018 (/ISO) Q91XP5 (/ISO) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | P07727 (/IDA) |
Glycine-gated chloride channel complex GO:0016935
A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts.
|
1 | Q91XP5 (/ISO) |
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
1 | Q64018 (/IDA) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | Q64018 (/IDA) |
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | Q64018 (/ISO) |
Calyx of Held GO:0044305
The terminal specialization of a calyciferous axon which forms large synapses in the mammalian auditory central nervous system.
|
1 | P07727 (/IDA) |
Calyx of Held GO:0044305
The terminal specialization of a calyciferous axon which forms large synapses in the mammalian auditory central nervous system.
|
1 | Q64018 (/ISO) |
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
|
1 | Q64018 (/IDA) |
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
|
1 | Q64018 (/IDA) |
Inhibitory synapse GO:0060077
A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell.
|
1 | Q64018 (/IDA) |
Integral component of presynaptic membrane GO:0099056
The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P07727 (/IDA) |
Integral component of presynaptic membrane GO:0099056
The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q64018 (/ISO) |