CATH Superfamily 2.70.150.10
Calcium-transporting ATPase, cytoplasmic transduction domain A
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Calcium-transporting ATPase, cytoplasmic transduction domain A
".
FunFam 64: Cation-transporting ATPase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
2 | Q12697 (/IDA) Q12697 (/IDA) |
|
Ion transmembrane transporter activity, phosphorylative mechanism GO:0015662
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate.
|
2 | Q12697 (/ISS) Q12697 (/ISS) |
|
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
|
2 | Q12697 (/IDA) Q12697 (/IDA) |
|
Cupric ion binding GO:1903135
Interacting selectively and non-covalently with cupric ion, copper(2+).
|
2 | Q12697 (/IDA) Q12697 (/IDA) |
|
ATPase-coupled transmembrane transporter activity GO:0042626
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
|
1 | O74431 (/ISM) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular zinc ion homeostasis GO:0006882
Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell.
|
2 | Q12697 (/IMP) Q12697 (/IMP) |
|
Cellular manganese ion homeostasis GO:0030026
Any process involved in the maintenance of an internal steady state of manganese ions at the level of a cell.
|
2 | Q12697 (/IMP) Q12697 (/IMP) |
|
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
|
2 | Q12697 (/ISS) Q12697 (/ISS) |
|
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
|
1 | O74431 (/ISM) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
|
2 | Q12697 (/HDA) Q12697 (/HDA) |
|
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
|
2 | Q12697 (/IDA) Q12697 (/IDA) |
|
Vacuole-mitochondrion membrane contact site GO:1990816
A zone of apposition between the vacuolar membrane and the mitochondrial outer membrane, important for transfer of lipids between the two organelles.
|
2 | Q12697 (/IDA) Q12697 (/IDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | O74431 (/HDA) |
