The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 32: Arrestin domain-containing protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding, bridging involved in substrate recognition for ubiquitination GO:1990756
The binding activity of a molecule that brings together a ubiquitin ligase and its substrate. Usually mediated by F-box BTB/POZ domain proteins.
2 B0BNL6 (/ISS) Q99KN1 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q8N5I2 (/IPI)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
1 Q8N5I2 (/IPI)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
1 Q99KN1 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q8N5I2 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q99KN1 (/ISO)
Protein binding, bridging involved in substrate recognition for ubiquitination GO:1990756
The binding activity of a molecule that brings together a ubiquitin ligase and its substrate. Usually mediated by F-box BTB/POZ domain proteins.
1 Q8N5I2 (/IMP)
Protein binding, bridging involved in substrate recognition for ubiquitination GO:1990756
The binding activity of a molecule that brings together a ubiquitin ligase and its substrate. Usually mediated by F-box BTB/POZ domain proteins.
1 Q99KN1 (/ISO)
Arrestin family protein binding GO:1990763
Interacting selectively and non-covalently with any member of the arrestin family, proteins involved in agonist-mediated desensitization of G protein-coupled receptors.
1 Q8N5I2 (/IPI)
Arrestin family protein binding GO:1990763
Interacting selectively and non-covalently with any member of the arrestin family, proteins involved in agonist-mediated desensitization of G protein-coupled receptors.
1 Q99KN1 (/ISO)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
2 B0BNL6 (/ISS) Q99KN1 (/ISS)
Extracellular transport GO:0006858
The transport of substances that occurs outside cells.
2 B0BNL6 (/ISS) Q99KN1 (/ISS)
Protein transport GO:0015031
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 B0BNL6 (/ISS) Q99KN1 (/ISS)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
2 B0BNL6 (/ISS) Q99KN1 (/ISS)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
2 B0BNL6 (/ISS) Q99KN1 (/ISS)
Extracellular vesicle biogenesis GO:0140112
The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.
2 B0BNL6 (/ISS) Q99KN1 (/ISS)
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
1 Q8N5I2 (/IMP)
Extracellular transport GO:0006858
The transport of substances that occurs outside cells.
1 Q8N5I2 (/IMP)
Extracellular transport GO:0006858
The transport of substances that occurs outside cells.
1 Q99KN1 (/ISO)
Protein transport GO:0015031
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q8N5I2 (/IMP)
Protein transport GO:0015031
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q99KN1 (/ISO)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
1 Q8N5I2 (/IMP)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
1 Q99KN1 (/ISO)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
1 Q8N5I2 (/IMP)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
1 Q99KN1 (/ISO)
Extracellular vesicle biogenesis GO:0140112
The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.
1 Q8N5I2 (/IMP)
Extracellular vesicle biogenesis GO:0140112
The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.
1 Q99KN1 (/ISO)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 B0BNL6 (/ISS) Q99KN1 (/ISS)
Extracellular vesicle GO:1903561
Any vesicle that is part of the extracellular region.
2 B0BNL6 (/ISS) Q99KN1 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q8N5I2 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q99KN1 (/ISO)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
1 Q8N5I2 (/IDA)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
1 Q99KN1 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q8N5I2 (/HDA)
Extracellular vesicle GO:1903561
Any vesicle that is part of the extracellular region.
1 Q8N5I2 (/IDA)
Extracellular vesicle GO:1903561
Any vesicle that is part of the extracellular region.
1 Q99KN1 (/ISO)
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