The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Resistin head domain
".
FunFam 1: Resistin-like beta
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Hormone activity GO:0005179
The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
|
2 | Q70Q42 (/TAS) Q8K4J7 (/TAS) |
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
1 | G3V686 (/NAS) |
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of collagen metabolic process GO:0010714
Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
|
3 | Q99P87 (/ISO) Q99P87 (/ISO) Q99P87 (/ISO) |
|
Positive regulation of smooth muscle cell migration GO:0014911
Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.
|
3 | Q99P87 (/ISO) Q99P87 (/ISO) Q99P87 (/ISO) |
|
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
3 | Q99P87 (/ISO) Q99P87 (/ISO) Q99P87 (/ISO) |
|
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
|
3 | Q99P87 (/ISO) Q99P87 (/ISO) Q99P87 (/ISO) |
|
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
|
3 | Q99P87 (/ISO) Q99P87 (/ISO) Q99P87 (/ISO) |
|
Positive regulation of synaptic transmission GO:0050806
Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
|
3 | Q99P87 (/ISO) Q99P87 (/ISO) Q99P87 (/ISO) |
|
Positive regulation of lipid catabolic process GO:0050996
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
|
3 | Q762I5 (/IMP) Q762I5 (/IMP) Q762I5 (/IMP) |
|
Negative regulation of feeding behavior GO:2000252
Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior.
|
3 | Q99P87 (/ISO) Q99P87 (/ISO) Q99P87 (/ISO) |
|
Positive regulation of progesterone secretion GO:2000872
Any process that activates or increases the frequency, rate or extent of progesterone secretion.
|
3 | Q99P87 (/ISO) Q99P87 (/ISO) Q99P87 (/ISO) |
|
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
|
2 | Q70Q42 (/IEP) Q8K4J7 (/IEP) |
|
Response to mechanical stimulus GO:0009612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
|
2 | Q70Q42 (/IEP) Q8K4J7 (/IEP) |
|
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
2 | Q70Q42 (/IMP) Q8K4J7 (/IMP) |
|
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
|
2 | Q70Q42 (/IMP) Q8K4J7 (/IMP) |
|
Positive regulation of synaptic transmission GO:0050806
Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
|
2 | Q70Q42 (/IDA) Q8K4J7 (/IDA) |
|
Negative regulation of feeding behavior GO:2000252
Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior.
|
2 | Q70Q42 (/IDA) Q8K4J7 (/IDA) |
|
Positive regulation of progesterone secretion GO:2000872
Any process that activates or increases the frequency, rate or extent of progesterone secretion.
|
2 | Q70Q42 (/IDA) Q8K4J7 (/IDA) |
|
Myeloid dendritic cell chemotaxis GO:0002408
The movement of a myeloid dendritic cell in response to an external stimulus.
|
1 | Q8K426 (/IPI) |
|
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
1 | Q9BQ08 (/NAS) |
|
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
|
1 | Q99P86 (/IEP) |
|
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
|
1 | Q9HD89 (/TAS) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
9 | Q70Q42 (/IDA) Q762I5 (/IDA) Q762I5 (/IDA) Q762I5 (/IDA) Q8K426 (/IDA) Q8K4J7 (/IDA) Q99P87 (/IDA) Q99P87 (/IDA) Q99P87 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
4 | Q99P86 (/IDA) Q99P87 (/IDA) Q99P87 (/IDA) Q99P87 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
4 | Q99P87 (/TAS) Q99P87 (/TAS) Q99P87 (/TAS) Q9HD89 (/TAS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
3 | Q99P87 (/ISO) Q99P87 (/ISO) Q99P87 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | Q99P87 (/ISO) Q99P87 (/ISO) Q99P87 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q70Q42 (/IDA) Q8K4J7 (/IDA) |
|
Azurophil granule lumen GO:0035578
The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
|
1 | Q9HD89 (/TAS) |
|
Specific granule lumen GO:0035580
The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
|
1 | Q9HD89 (/TAS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q9HD89 (/HDA) |