The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Beta-1,3-glucan-recognition protein, N-terminal domain
".
FunFam 1: Beta-1,3-glucan-binding protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Signaling pattern recognition receptor activity GO:0008329
Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity.
|
4 | Q8ISB6 (/IDA) Q8MU95 (/IDA) Q9NJ98 (/IDA) Q9NL89 (/IDA) |
|
Carbohydrate binding GO:0030246
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
|
2 | A0ZWY4 (/ISS) A1ZBU5 (/ISS) |
|
Lipopolysaccharide binding GO:0001530
Interacting selectively and non-covalently with lipopolysaccharide.
|
1 | Q9NHA8 (/IDA) |
|
(1->3)-beta-D-glucan binding GO:0001872
Interacting selectively and non-covalently with (1->3)-beta-D-glucans.
|
1 | Q9NHA8 (/IDA) |
|
Signaling pattern recognition receptor activity GO:0008329
Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity.
|
1 | Q9NHA8 (/ISS) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
|
5 | Q76DI2 (/IDA) Q8ISB6 (/IDA) Q8MU95 (/IDA) Q9NJ98 (/IDA) Q9NL89 (/IDA) |
|
Cell surface pattern recognition receptor signaling pathway GO:0002752
Any series of molecular signals generated as a consequence of a cell surface pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.
|
4 | Q8ISB6 (/IDA) Q8MU95 (/IDA) Q9NJ98 (/IDA) Q9NL89 (/IDA) |
|
Detection of biotic stimulus GO:0009595
The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal.
|
2 | A0ZWY4 (/ISS) A1ZBU5 (/ISS) |
|
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
|
2 | O96363 (/ISS) Q9NHA8 (/ISS) |
|
Pattern recognition receptor signaling pathway GO:0002221
Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.
|
1 | Q9NHA8 (/ISS) |
|
Innate immune response-activating signal transduction GO:0002758
The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an innate immune response.
|
1 | Q9NHA8 (/ISS) |
|
Response to fungus GO:0009620
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.
|
1 | A1ZBU5 (/HEP) |
|
Detection of molecule of fungal origin GO:0032491
The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal.
|
1 | Q9NHA8 (/IDA) |
|
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
1 | Q76DI2 (/IDA) |
|
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
1 | O96363 (/ISS) |
|
Positive regulation of Toll signaling pathway GO:0045752
Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway.
|
1 | Q9NHA8 (/IGI) |
|
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
1 | A0ZWY4 (/IEP) |
|
Defense response to other organism GO:0098542
Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.
|
1 | A1ZBU5 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
5 | Q76DI2 (/IDA) Q8ISB6 (/IDA) Q8MU95 (/IDA) Q9NJ98 (/IDA) Q9NL89 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | O96363 (/ISS) Q9NHA8 (/ISS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | A0ZWY4 (/ISS) A1ZBU5 (/ISS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | Q9NHA8 (/IDA) |
