The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 24: sodium/calcium exchanger 1-like

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium:sodium antiporter activity GO:0005432
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in).
12 A0A0B4K6A6 (/IDA) A0A0B4K6E2 (/IDA) A0A0B4K6R7 (/IDA) A0A0B4K790 (/IDA) A0A0B4LHD7 (/IDA) A4UQV6 (/IDA) B3DJ26 (/IDA) O18367 (/IDA) Q1JQ21 (/IDA) Q24413 (/IDA)
(2 more)
Calcium:sodium antiporter activity GO:0005432
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in).
10 A0A0B4K6A6 (/IMP) A0A0B4K6E2 (/IMP) A0A0B4K6R7 (/IMP) A0A0B4K790 (/IMP) A0A0B4LHD7 (/IMP) O18367 (/IMP) Q1JQ21 (/IMP) Q24413 (/IMP) Q501W6 (/IMP) Q9VDG5 (/IMP)
Calcium:sodium antiporter activity GO:0005432
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in).
8 A0A0B4K6A6 (/TAS) A0A0B4K6E2 (/TAS) A0A0B4K6R7 (/TAS) A0A0B4K790 (/TAS) A0A0B4LHD7 (/TAS) O18367 (/TAS) Q24413 (/TAS) Q9VDG5 (/TAS)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
8 A0A0B4K6A6 (/IDA) A0A0B4K6E2 (/IDA) A0A0B4K6R7 (/IDA) A0A0B4K790 (/IDA) A0A0B4LHD7 (/IDA) O18367 (/IDA) Q24413 (/IDA) Q9VDG5 (/IDA)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
8 A0A0B4K6A6 (/IMP) A0A0B4K6E2 (/IMP) A0A0B4K6R7 (/IMP) A0A0B4K790 (/IMP) A0A0B4LHD7 (/IMP) O18367 (/IMP) Q24413 (/IMP) Q9VDG5 (/IMP)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
8 A0A0B4K6A6 (/IMP) A0A0B4K6E2 (/IMP) A0A0B4K6R7 (/IMP) A0A0B4K790 (/IMP) A0A0B4LHD7 (/IMP) O18367 (/IMP) Q24413 (/IMP) Q9VDG5 (/IMP)
Neuromuscular process controlling posture GO:0050884
Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.
8 A0A0B4K6A6 (/IMP) A0A0B4K6E2 (/IMP) A0A0B4K6R7 (/IMP) A0A0B4K790 (/IMP) A0A0B4LHD7 (/IMP) O18367 (/IMP) Q24413 (/IMP) Q9VDG5 (/IMP)
Heart looping GO:0001947
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
2 A4UQV6 (/IMP) B3DJ26 (/IMP)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q1JQ21 (/IDA) Q501W6 (/IDA)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q1JQ21 (/IMP) Q501W6 (/IMP)
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
2 Q1JQ21 (/IMP) Q501W6 (/IMP)
Determination of left/right symmetry GO:0007368
The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
2 A4UQV6 (/IGI) B3DJ26 (/IGI)
Determination of left/right symmetry GO:0007368
The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
2 A4UQV6 (/IMP) B3DJ26 (/IMP)
Skeletal muscle tissue development GO:0007519
The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
2 A4UQV6 (/IMP) B3DJ26 (/IMP)
Regulation of heart contraction GO:0008016
Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.
2 Q1JQ21 (/IGI) Q501W6 (/IGI)
Regulation of heart contraction GO:0008016
Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.
2 Q1JQ21 (/IMP) Q501W6 (/IMP)
Fluid transport GO:0042044
The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 A4UQV6 (/IMP) B3DJ26 (/IMP)
Sarcomere organization GO:0045214
The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
2 Q1JQ21 (/IMP) Q501W6 (/IMP)
Regulation of cytosolic calcium ion concentration GO:0051480
Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings.
2 A4UQV6 (/IMP) B3DJ26 (/IMP)
Heart contraction GO:0060047
The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.
2 A4UQV6 (/IMP) B3DJ26 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q1JQ21 (/NAS) Q501W6 (/NAS)
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