The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Superoxide dismutase, copper/zinc binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Copper chaperone for superoxide dismutase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Superoxide dismutase copper chaperone activity GO:0016532
A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity.
3 A1Z850 (/IDA) E1JH26 (/IDA) Q9BLY4 (/IDA)
Superoxide dismutase activity GO:0004784
Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.
2 G5ECR5 (/IDA) P34461 (/IDA)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
2 O14618 (/IDA) O14618 (/IDA)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
2 Q9WU84 (/ISO) Q9WU84 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 O14618 (/IPI) O14618 (/IPI)
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
2 O14618 (/TAS) O14618 (/TAS)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
2 Q9WU84 (/ISO) Q9WU84 (/ISO)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
2 O14618 (/HDA) O14618 (/HDA)
Superoxide dismutase copper chaperone activity GO:0016532
A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity.
1 Q9JK72 (/TAS)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 Q9JK72 (/IDA)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
3 A1Z850 (/IMP) E1JH26 (/IMP) Q9BLY4 (/IMP)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
3 A1Z850 (/IMP) E1JH26 (/IMP) Q9BLY4 (/IMP)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
3 A1Z850 (/IDA) E1JH26 (/IDA) Q9BLY4 (/IDA)
Superoxide metabolic process GO:0006801
The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
2 G5ECR5 (/IDA) P34461 (/IDA)
Superoxide metabolic process GO:0006801
The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
2 O14618 (/TAS) O14618 (/TAS)
Protein maturation by copper ion transfer GO:0015680
A process that contributes to the delivery of copper ions to a target protein.
2 O14618 (/TAS) O14618 (/TAS)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 O14618 (/TAS) O14618 (/TAS)
Positive regulation of oxidoreductase activity GO:0051353
Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
2 Q9WU84 (/IMP) Q9WU84 (/IMP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 A1Z850 (/IDA) E1JH26 (/IDA) O14618 (/IDA) O14618 (/IDA) Q9BLY4 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
3 A1Z850 (/IDA) E1JH26 (/IDA) Q9BLY4 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 G5ECR5 (/IDA) P34461 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 O14618 (/IDA) O14618 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9WU84 (/ISO) Q9WU84 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q9WU84 (/ISO) Q9WU84 (/ISO)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
2 Q9WU84 (/TAS) Q9WU84 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 O14618 (/TAS) O14618 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 G5ECR5 (/IDA) P34461 (/IDA)
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