The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"C2 domain
".
FunFam 111: synaptotagmin-5 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 14 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
5 | O00445 (/IDA) O00445 (/IDA) O00445 (/IDA) O00445 (/IDA) O00445 (/IDA) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
2 | P47861 (/ISS) Q9R0N5 (/ISS) |
|
Calcium-dependent phospholipid binding GO:0005544
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.
|
2 | P47861 (/IDA) Q9R0N5 (/IDA) |
|
SNARE binding GO:0000149
Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
|
1 | Q9R0N5 (/IDA) |
|
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
|
1 | Q9R0N5 (/IDA) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | Q9R0N5 (/ISO) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | Q9R0N5 (/TAS) |
|
Calcium-dependent phospholipid binding GO:0005544
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.
|
1 | Q9R0N5 (/ISO) |
|
Phosphatidylinositol-4,5-bisphosphate binding GO:0005546
Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
|
1 | Q9R0N5 (/IDA) |
|
Syntaxin binding GO:0019905
Interacting selectively and non-covalently with a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse.
|
1 | P47861 (/IDA) |
|
Syntaxin binding GO:0019905
Interacting selectively and non-covalently with a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse.
|
1 | Q9R0N5 (/ISO) |
|
Clathrin binding GO:0030276
Interacting selectively and non-covalently with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.
|
1 | P47861 (/IDA) |
|
Clathrin binding GO:0030276
Interacting selectively and non-covalently with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.
|
1 | Q9R0N5 (/ISO) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
1 | Q9R0N5 (/IPI) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
|
5 | O00445 (/TAS) O00445 (/TAS) O00445 (/TAS) O00445 (/TAS) O00445 (/TAS) |
|
Calcium-ion regulated exocytosis GO:0017156
The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.
|
1 | P47861 (/NAS) |
|
Regulation of calcium ion-dependent exocytosis GO:0017158
Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis.
|
1 | Q9R0N5 (/IMP) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9R0N5 (/TAS) |
|
Dense core granule GO:0031045
Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted.
|
1 | Q9R0N5 (/IDA) |
|
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
1 | Q9R0N5 (/IDA) |
|
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | Q9R0N5 (/IDA) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q9R0N5 (/IDA) |
|
Integral component of neuronal dense core vesicle membrane GO:0099066
The component of the neuronal dense core vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q9R0N5 (/IDA) |
|
Proximal neuron projection GO:1990769
The portion of an axon or dendrite that is close to the neuronal cell body.
|
1 | Q9R0N5 (/IDA) |
