The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Golgi alpha-mannosidase II
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 20: Pancreatic alpha-amylase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 15 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Alpha-amylase activity GO:0004556
Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.
5 P00688 (/ISS) P00689 (/ISS) P00690 (/ISS) P19961 (/ISS) P56634 (/ISS)
Alpha-amylase activity GO:0004556
Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.
5 E9PSQ1 (/TAS) P04746 (/TAS) P08144 (/TAS) P81641 (/TAS) Q99N59 (/TAS)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
4 B0KZK1 (/ISS) P00688 (/ISS) P00689 (/ISS) P00690 (/ISS)
Chloride ion binding GO:0031404
Interacting selectively and non-covalently with chloride ions (Cl-).
4 B0KZK1 (/ISS) P00688 (/ISS) P00689 (/ISS) P00690 (/ISS)
Alpha-amylase activity GO:0004556
Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.
3 B0KZK1 (/IDA) P00689 (/IDA) P04746 (/IDA)
Alpha-amylase activity GO:0004556
Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.
2 P00687 (/ISO) P00688 (/ISO)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
2 P04746 (/IDA) P56634 (/IDA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
2 P08144 (/TAS) P81641 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P00689 (/IPI) P04745 (/IPI)
Amylase activity GO:0016160
Catalysis of the hydrolysis of amylose or an amylose derivative.
2 P00687 (/IDA) P00688 (/IDA)
Chloride ion binding GO:0031404
Interacting selectively and non-covalently with chloride ions (Cl-).
2 P04746 (/IDA) P56634 (/IDA)
Alpha-amylase activity GO:0004556
Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.
1 P00689 (/IMP)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 P00687 (/ISO)
Amylase activity GO:0016160
Catalysis of the hydrolysis of amylose or an amylose derivative.
1 O18408 (/ISS)
Chloride ion binding GO:0031404
Interacting selectively and non-covalently with chloride ions (Cl-).
1 P00687 (/ISO)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Carbohydrate catabolic process GO:0016052
The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
4 P00688 (/ISS) P00689 (/ISS) P00690 (/ISS) P56634 (/ISS)
Cellular response to estrogen stimulus GO:0071391
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
3 A0A0R4IST0 (/IDA) F1RD28 (/IDA) Q7SYK9 (/IDA)
Carbohydrate metabolic process GO:0005975
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
2 E9PSQ1 (/IEP) Q99N59 (/IEP)
Carbohydrate metabolic process GO:0005975
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
2 P08144 (/TAS) P81641 (/TAS)
Carbohydrate metabolic process GO:0005975
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
1 P04746 (/NAS)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
1 P00687 (/IEP)
Carbohydrate catabolic process GO:0016052
The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
1 P04746 (/IDA)
Carbohydrate catabolic process GO:0016052
The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
1 P00687 (/ISO)
Polysaccharide digestion GO:0044245
The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism.
1 P04746 (/TAS)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
6 E9PSQ1 (/IDA) P00687 (/IDA) P00688 (/IDA) P04745 (/IDA) P04746 (/IDA) Q99N59 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
3 P00688 (/ISS) P00689 (/ISS) P00690 (/ISS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
3 P04745 (/HDA) P04746 (/HDA) P19961 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 P08144 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 P04746 (/TAS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P04745 (/HDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P00687 (/ISO)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P04746 (/TAS)
CATH-Gene3D is a Global Biodata Core Resource Learn more...