The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Mu homology domain, subdomain B
".
FunFam 9: AP-3 complex subunit mu-1-like protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
32 |
P53676 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
(22 more) |
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
|
31 |
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
Q9Y2T2 (/IPI)
(21 more) |
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
|
1 | Q9JKC8 (/ISO) |
Cargo adaptor activity GO:0140312
Binding directly to the structural scaffolding elements of a vesicle coat (such as clathrin or COPII), and bridging the membrane, cargo, and membrane deformation machinery.
|
1 | O76928 (/ISS) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Anterograde axonal transport GO:0008089
The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons.
|
71 |
P53676 (/ISS)
P53677 (/ISS)
P53677 (/ISS)
P53677 (/ISS)
P53677 (/ISS)
P53677 (/ISS)
P53678 (/ISS)
Q24K11 (/ISS)
Q5R478 (/ISS)
Q5R478 (/ISS)
(61 more) |
Anterograde synaptic vesicle transport GO:0048490
The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse.
|
71 |
P53676 (/ISS)
P53677 (/ISS)
P53677 (/ISS)
P53677 (/ISS)
P53677 (/ISS)
P53677 (/ISS)
P53678 (/ISS)
Q24K11 (/ISS)
Q5R478 (/ISS)
Q5R478 (/ISS)
(61 more) |
Protein targeting to lysosome GO:0006622
The process of directing proteins towards the lysosome using signals contained within the protein.
|
31 |
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
(21 more) |
Anterograde axonal transport GO:0008089
The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons.
|
2 | Q8R2R9 (/IMP) Q9JKC8 (/IMP) |
Anterograde synaptic vesicle transport GO:0048490
The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse.
|
2 | Q8R2R9 (/IMP) Q9JKC8 (/IMP) |
Ommochrome biosynthetic process GO:0006727
The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.
|
1 | O76928 (/IMP) |
Exocytosis GO:0006887
A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.
|
1 | O76928 (/IMP) |
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
|
1 | O76928 (/IMP) |
Notch receptor processing GO:0007220
The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor.
|
1 | O76928 (/IMP) |
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.
|
1 | P53678 (/NAS) |
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
|
1 | O76928 (/IMP) |
Intracellular transport GO:0046907
The directed movement of substances within a cell.
|
1 | P53678 (/NAS) |
Intracellular transport GO:0046907
The directed movement of substances within a cell.
|
1 | O76928 (/TAS) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
32 |
Q8NDP0 (/HDA)
Q9Y2T2 (/HDA)
Q9Y2T2 (/HDA)
Q9Y2T2 (/HDA)
Q9Y2T2 (/HDA)
Q9Y2T2 (/HDA)
Q9Y2T2 (/HDA)
Q9Y2T2 (/HDA)
Q9Y2T2 (/HDA)
Q9Y2T2 (/HDA)
(22 more) |
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
31 |
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
Q9Y2T2 (/TAS)
(21 more) |
AP-type membrane coat adaptor complex GO:0030119
Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa).
|
5 | P53677 (/TAS) P53677 (/TAS) P53677 (/TAS) P53677 (/TAS) P53677 (/TAS) |
AP-3 adaptor complex GO:0030123
A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).
|
1 | O76928 (/ISS) |