The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Mu homology domain, subdomain B
".
FunFam 5: SH3-containing GRB2-like protein 3-interacting pro...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
5 | E1BJV6 (/ISS) P0DJJ3 (/ISS) Q5RDL3 (/ISS) Q6IZA3 (/ISS) Q9BQI5 (/ISS) |
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
|
5 | E1BJV6 (/ISS) P0DJJ3 (/ISS) Q5RDL3 (/ISS) Q6IZA3 (/ISS) Q9BQI5 (/ISS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q8VD37 (/IPI) Q9BQI5 (/IPI) |
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
|
2 | P0DJJ3 (/IPI) Q8VD37 (/IPI) |
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
1 | Q8VD37 (/IDA) |
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
|
1 | Q8VD37 (/IDA) |
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
|
1 | Q8VD37 (/ISO) |
SH3 domain binding GO:0017124
Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
|
1 | Q9BQI5 (/IPI) |
SH3 domain binding GO:0017124
Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
|
1 | Q8VD37 (/ISO) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Positive regulation of receptor-mediated endocytosis GO:0048260
Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
|
5 | E1BJV6 (/ISS) P0DJJ3 (/ISS) Q5RDL3 (/ISS) Q6IZA3 (/ISS) Q9BQI5 (/ISS) |
Response to dietary excess GO:0002021
The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure.
|
4 | E1BJV6 (/ISS) Q5RDL3 (/ISS) Q8VD37 (/ISS) Q9BQI5 (/ISS) |
Energy homeostasis GO:0097009
Any process involved in the balance between food intake (energy input) and energy expenditure.
|
4 | E1BJV6 (/ISS) Q5RDL3 (/ISS) Q8VD37 (/ISS) Q9BQI5 (/ISS) |
Positive regulation of feeding behavior GO:2000253
Any process that activates or increases the frequency, rate or extent of feeding behavior.
|
4 | E1BJV6 (/ISS) Q5RDL3 (/ISS) Q8VD37 (/ISS) Q9BQI5 (/ISS) |
Response to dietary excess GO:0002021
The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure.
|
2 | P0DJJ3 (/IMP) Q6IZA3 (/IMP) |
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
|
2 | P0DJJ3 (/IEP) Q6IZA3 (/IEP) |
Energy homeostasis GO:0097009
Any process involved in the balance between food intake (energy input) and energy expenditure.
|
2 | P0DJJ3 (/IMP) Q6IZA3 (/IMP) |
Positive regulation of feeding behavior GO:2000253
Any process that activates or increases the frequency, rate or extent of feeding behavior.
|
2 | P0DJJ3 (/IMP) Q6IZA3 (/IMP) |
Response to dietary excess GO:0002021
The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure.
|
1 | Q8VD37 (/ISO) |
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
|
1 | P0DJJ3 (/IMP) |
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
|
1 | Q8VD37 (/ISO) |
Positive regulation of receptor-mediated endocytosis GO:0048260
Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
|
1 | Q8VD37 (/IMP) |
Membrane organization GO:0061024
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
|
1 | Q9BQI5 (/TAS) |
Energy homeostasis GO:0097009
Any process involved in the balance between food intake (energy input) and energy expenditure.
|
1 | Q8VD37 (/ISO) |
Positive regulation of eating behavior GO:1904000
Any process that activates or increases the frequency, rate or extent of eating behavior.
|
1 | P0DJJ3 (/IMP) |
Positive regulation of eating behavior GO:1904000
Any process that activates or increases the frequency, rate or extent of eating behavior.
|
1 | Q8VD37 (/ISO) |
Positive regulation of feeding behavior GO:2000253
Any process that activates or increases the frequency, rate or extent of feeding behavior.
|
1 | Q8VD37 (/ISO) |
There are 17 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | E1BJV6 (/ISS) P0DJJ3 (/ISS) Q5RDL3 (/ISS) Q6IZA3 (/ISS) Q8VD37 (/ISS) |
AP-2 adaptor complex GO:0030122
A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).
|
5 | E1BJV6 (/ISS) P0DJJ3 (/ISS) Q5RDL3 (/ISS) Q6IZA3 (/ISS) Q9BQI5 (/ISS) |
Clathrin-coated vesicle GO:0030136
A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.
|
5 | E1BJV6 (/ISS) P0DJJ3 (/ISS) Q5RDL3 (/ISS) Q6IZA3 (/ISS) Q9BQI5 (/ISS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | E1BJV6 (/ISS) P0DJJ3 (/ISS) Q5RDL3 (/ISS) Q6IZA3 (/ISS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q8VD37 (/IDA) Q9BQI5 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9BQI5 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8VD37 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9BQI5 (/TAS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q8VD37 (/ISO) |
Clathrin-coated pit GO:0005905
A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.
|
1 | Q9BQI5 (/IDA) |
Clathrin-coated pit GO:0005905
A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.
|
1 | Q8VD37 (/ISO) |
AP-2 adaptor complex GO:0030122
A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).
|
1 | Q8VD37 (/IDA) |
Clathrin-coated vesicle GO:0030136
A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.
|
1 | Q8VD37 (/IDA) |
Terminal bouton GO:0043195
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
|
1 | P0DJJ3 (/HDA) |
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
|
1 | P0DJJ3 (/IDA) |
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
|
1 | P0DJJ3 (/IMP) |
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
|
1 | Q8VD37 (/ISO) |