The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 736: Junctional adhesion molecule-like

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
2 Q86YT9 (/IPI) Q86YT9 (/IPI)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
2 Q80UL9 (/ISO) Q80UL9 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q86YT9 (/IDA) Q86YT9 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q80UL9 (/ISO) Q80UL9 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q80UL9 (/ISS) Q80UL9 (/ISS)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
2 Q86YT9 (/IPI) Q86YT9 (/IPI)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
2 Q80UL9 (/ISO) Q80UL9 (/ISO)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
2 Q86YT9 (/IDA) Q86YT9 (/IDA)
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
2 Q86YT9 (/IMP) Q86YT9 (/IMP)
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
2 Q80UL9 (/ISO) Q80UL9 (/ISO)
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
2 Q80UL9 (/ISS) Q80UL9 (/ISS)
Neutrophil chemotaxis GO:0030593
The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
2 Q86YT9 (/IMP) Q86YT9 (/IMP)
Neutrophil chemotaxis GO:0030593
The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
2 Q80UL9 (/ISO) Q80UL9 (/ISO)
Monocyte extravasation GO:0035696
The migration of a monocyte from the blood vessels into the surrounding tissue.
2 Q86YT9 (/IMP) Q86YT9 (/IMP)
Monocyte extravasation GO:0035696
The migration of a monocyte from the blood vessels into the surrounding tissue.
2 Q80UL9 (/ISO) Q80UL9 (/ISO)
Monocyte extravasation GO:0035696
The migration of a monocyte from the blood vessels into the surrounding tissue.
2 Q80UL9 (/ISS) Q80UL9 (/ISS)
Gamma-delta T cell activation GO:0046629
The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
2 Q80UL9 (/IDA) Q80UL9 (/IDA)
Gamma-delta T cell activation GO:0046629
The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
2 Q86YT9 (/ISS) Q86YT9 (/ISS)
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
2 Q86YT9 (/TAS) Q86YT9 (/TAS)
Leukocyte migration GO:0050900
The movement of a leukocyte within or between different tissues and organs of the body.
2 Q86YT9 (/TAS) Q86YT9 (/TAS)
Positive regulation of epithelial cell proliferation involved in wound healing GO:0060054
Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.
2 Q80UL9 (/IDA) Q80UL9 (/IDA)
Positive regulation of epithelial cell proliferation involved in wound healing GO:0060054
Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.
2 Q86YT9 (/ISS) Q86YT9 (/ISS)
Neutrophil extravasation GO:0072672
The migration of a neutrophil from the blood vessels into the surrounding tissue.
2 Q86YT9 (/IMP) Q86YT9 (/IMP)
Neutrophil extravasation GO:0072672
The migration of a neutrophil from the blood vessels into the surrounding tissue.
2 Q80UL9 (/ISO) Q80UL9 (/ISO)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 Q80UL9 (/IDA) Q80UL9 (/IDA) Q86YT9 (/IDA) Q86YT9 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q80UL9 (/ISO) Q80UL9 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q86YT9 (/TAS) Q86YT9 (/TAS)
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
2 Q86YT9 (/IDA) Q86YT9 (/IDA)
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
2 Q80UL9 (/ISO) Q80UL9 (/ISO)
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
2 Q80UL9 (/ISS) Q80UL9 (/ISS)
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