The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 592: Fc receptor like 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q96LA5 (/IPI) Q96PJ5 (/IPI)
SH3/SH2 adaptor activity GO:0005070
Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68).
1 Q96LA5 (/IPI)
Coreceptor activity GO:0015026
Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.
1 Q96LA6 (/IDA)
Coreceptor activity GO:0015026
Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.
1 Q8R4Y0 (/ISO)
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
1 Q96P31 (/IPI)
Phosphatase binding GO:0019902
Interacting selectively and non-covalently with any phosphatase.
1 Q96P31 (/IPI)
Protein phosphatase binding GO:0019903
Interacting selectively and non-covalently with any protein phosphatase.
1 Q96P31 (/IPI)
Protein tyrosine kinase binding GO:1990782
Interacting selectively and non-covalently with protein tyrosine kinase.
1 Q96P31 (/IPI)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of immunoglobulin production GO:0002638
Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production.
1 Q96P31 (/IDA)
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
1 Q96LA5 (/NAS)
Positive regulation of B cell proliferation GO:0030890
Any process that activates or increases the rate or extent of B cell proliferation.
1 Q96P31 (/IDA)
Regulation of toll-like receptor 9 signaling pathway GO:0034163
Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway.
1 Q96P31 (/IDA)
B cell activation GO:0042113
The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
1 Q96LA6 (/IDA)
B cell activation GO:0042113
The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
1 Q8R4Y0 (/ISO)
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
1 Q96P31 (/IDA)
Regulation of B cell differentiation GO:0045577
Any process that modulates the frequency, rate or extent of B cell differentiation.
1 Q96P31 (/IDA)
Negative regulation of B cell receptor signaling pathway GO:0050859
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
1 Q96P31 (/IDA)
Regulation of B cell activation GO:0050864
Any process that modulates the frequency, rate or extent of B cell activation.
1 Q96P31 (/IDA)
Regulation of calcium ion import GO:0090279
Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
1 Q96P31 (/IDA)
Positive regulation of protein serine/threonine phosphatase activity GO:1905184
Any process that activates or increases the frequency, rate or extent of protein serine/threonine phosphatase activity.
1 Q96P31 (/IDA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
4 Q96LA5 (/IDA) Q96LA6 (/IDA) Q96P31 (/IDA) Q96PJ5 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q8R4Y0 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q96LA5 (/NAS)
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