The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 588: Cell adhesion molecule 4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Vascular endothelial growth factor receptor 2 binding GO:0043184
Interacting selectively and non-covalently with vascular endothelial growth factor receptor 2.
8 Q8NFZ8 (/IPI) Q8NFZ8 (/IPI) Q8NFZ8 (/IPI) Q8NFZ8 (/IPI) Q8NFZ8 (/IPI) Q8NFZ8 (/IPI) Q8NFZ8 (/IPI) Q8R464 (/IPI)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 B0CLV3 (/IPI)
Protein phosphatase binding GO:0019903
Interacting selectively and non-covalently with any protein phosphatase.
1 Q8R464 (/IPI)
Receptor tyrosine kinase binding GO:0030971
Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity.
1 Q8R464 (/IPI)
Vascular endothelial growth factor receptor 1 binding GO:0043183
Interacting selectively and non-covalently with vascular endothelial growth factor receptor 1.
1 Q8R464 (/IPI)
Vascular endothelial growth factor receptor 2 binding GO:0043184
Interacting selectively and non-covalently with vascular endothelial growth factor receptor 2.
1 Q8R464 (/ISO)

There are 27 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of protein phosphorylation GO:0001932
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
8 Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8R464 (/IMP)
Negative regulation of protein phosphorylation GO:0001933
Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
8 Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8R464 (/IMP)
Negative regulation of peptidyl-threonine phosphorylation GO:0010801
Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
8 Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8R464 (/IMP)
Negative regulation of vascular endothelial growth factor receptor signaling pathway GO:0030948
Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
8 Q1WIM1 (/ISS) Q8NFZ8 (/ISS) Q8NFZ8 (/ISS) Q8NFZ8 (/ISS) Q8NFZ8 (/ISS) Q8NFZ8 (/ISS) Q8NFZ8 (/ISS) Q8NFZ8 (/ISS)
Regulation of Rac protein signal transduction GO:0035020
Any process that modulates the frequency, rate or extent of Rac protein signal transduction.
8 Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8R464 (/IMP)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
8 Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8R464 (/IMP)
Negative regulation of peptidyl-tyrosine phosphorylation GO:0050732
Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
8 Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8R464 (/IMP)
Regulation of wound healing GO:0061041
Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
8 Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8R464 (/IMP)
Negative regulation of vascular endothelial growth factor signaling pathway GO:1900747
Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway.
8 Q1WIM1 (/ISS) Q8NFZ8 (/ISS) Q8NFZ8 (/ISS) Q8NFZ8 (/ISS) Q8NFZ8 (/ISS) Q8NFZ8 (/ISS) Q8NFZ8 (/ISS) Q8NFZ8 (/ISS)
Regulation of cell motility GO:2000145
Any process that modulates the frequency, rate or extent of cell motility.
8 Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8NFZ8 (/IMP) Q8R464 (/IMP)
Bulbus arteriosus formation GO:0003234
The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart.
3 B0CLV3 (/IMP) F1QF23 (/IMP) Q5U3R8 (/IMP)
Regulation of protein phosphorylation GO:0001932
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
1 Q8R464 (/ISO)
Negative regulation of protein phosphorylation GO:0001933
Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
1 Q8R464 (/ISO)
Negative regulation of peptidyl-threonine phosphorylation GO:0010801
Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
1 Q8R464 (/ISO)
Negative regulation of peptidyl-threonine phosphorylation GO:0010801
Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
1 Q1WIM1 (/ISS)
Negative regulation of vascular endothelial growth factor receptor signaling pathway GO:0030948
Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
1 Q8R464 (/IMP)
Regulation of Rac protein signal transduction GO:0035020
Any process that modulates the frequency, rate or extent of Rac protein signal transduction.
1 Q8R464 (/ISO)
Regulation of Rac protein signal transduction GO:0035020
Any process that modulates the frequency, rate or extent of Rac protein signal transduction.
1 Q1WIM1 (/ISS)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
1 Q8R464 (/ISO)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
1 Q1WIM1 (/ISS)
Negative regulation of peptidyl-tyrosine phosphorylation GO:0050732
Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
1 Q8R464 (/ISO)
Negative regulation of peptidyl-tyrosine phosphorylation GO:0050732
Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
1 Q1WIM1 (/ISS)
Regulation of wound healing GO:0061041
Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
1 Q8R464 (/ISO)
Regulation of wound healing GO:0061041
Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
1 Q1WIM1 (/ISS)
Negative regulation of vascular endothelial growth factor signaling pathway GO:1900747
Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway.
1 Q8R464 (/IMP)
Regulation of cell motility GO:2000145
Any process that modulates the frequency, rate or extent of cell motility.
1 Q8R464 (/ISO)
Regulation of cell motility GO:2000145
Any process that modulates the frequency, rate or extent of cell motility.
1 Q1WIM1 (/ISS)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell leading edge GO:0031252
The area of a motile cell closest to the direction of movement.
7 Q8NFZ8 (/IDA) Q8NFZ8 (/IDA) Q8NFZ8 (/IDA) Q8NFZ8 (/IDA) Q8NFZ8 (/IDA) Q8NFZ8 (/IDA) Q8NFZ8 (/IDA)
Cell-cell contact zone GO:0044291
Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle.
7 Q8NFZ8 (/IDA) Q8NFZ8 (/IDA) Q8NFZ8 (/IDA) Q8NFZ8 (/IDA) Q8NFZ8 (/IDA) Q8NFZ8 (/IDA) Q8NFZ8 (/IDA)
Cell leading edge GO:0031252
The area of a motile cell closest to the direction of movement.
2 Q1WIM1 (/ISS) Q8R464 (/ISS)
Cell-cell contact zone GO:0044291
Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle.
2 Q1WIM1 (/ISS) Q8R464 (/ISS)
Cell leading edge GO:0031252
The area of a motile cell closest to the direction of movement.
1 Q8R464 (/ISO)
Cell-cell contact zone GO:0044291
Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle.
1 Q8R464 (/ISO)
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