The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 375: Sodium channel beta 1 subunit
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
11 |
Q8BHK2 (/IPI)
Q8BHK2 (/IPI)
Q9NY72 (/IPI)
Q9NY72 (/IPI)
Q9NY72 (/IPI)
Q9NY72 (/IPI)
Q9NY72 (/IPI)
Q9NY72 (/IPI)
Q9NY72 (/IPI)
Q9NY72 (/IPI)
(1 more) |
|
Voltage-gated sodium channel activity involved in cardiac muscle cell action potential GO:0086006
Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
11 |
Q8BHK2 (/IMP)
Q8BHK2 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
(1 more) |
|
Voltage-gated sodium channel activity GO:0005248
Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
9 | Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) |
|
Sodium channel regulator activity GO:0017080
Modulates the activity of a sodium channel.
|
9 | Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) |
|
Sodium channel regulator activity GO:0017080
Modulates the activity of a sodium channel.
|
9 | Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) |
|
Voltage-gated sodium channel activity involved in cardiac muscle cell action potential GO:0086006
Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
9 | Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) |
|
Voltage-gated sodium channel activity GO:0005248
Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
2 | A0A0H2UKN7 (/IMP) B3F0A3 (/IMP) |
|
Sodium channel regulator activity GO:0017080
Modulates the activity of a sodium channel.
|
2 | Q8BHK2 (/ISO) Q8BHK2 (/ISO) |
|
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
2 | Q8BHK2 (/ISO) Q8BHK2 (/ISO) |
|
Voltage-gated sodium channel activity involved in cardiac muscle cell action potential GO:0086006
Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
2 | Q8BHK2 (/ISO) Q8BHK2 (/ISO) |
Showing 1 to 10 of 10 entries
There are 43 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of atrial cardiac muscle cell membrane depolarization GO:0060371
Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte.
|
11 |
Q8BHK2 (/IMP)
Q8BHK2 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
(1 more) |
|
Ventricular cardiac muscle cell action potential GO:0086005
An action potential that occurs in a ventricular cardiac muscle cell.
|
11 |
Q8BHK2 (/IMP)
Q8BHK2 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
Q9NY72 (/IMP)
(1 more) |
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
9 | Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) |
|
Positive regulation of heart rate GO:0010460
Any process that activates or increases the frequency or rate of heart contraction.
|
9 | Q9NY72 (/ISS) Q9NY72 (/ISS) Q9NY72 (/ISS) Q9NY72 (/ISS) Q9NY72 (/ISS) Q9NY72 (/ISS) Q9NY72 (/ISS) Q9NY72 (/ISS) Q9NY72 (/ISS) |
|
Positive regulation of sodium ion transport GO:0010765
Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
9 | Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) |
|
Positive regulation of sodium ion transport GO:0010765
Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
9 | Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) |
|
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
9 | Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) |
|
Membrane depolarization GO:0051899
The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.
|
9 | Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) |
|
Cardiac muscle contraction GO:0060048
Muscle contraction of cardiac muscle tissue.
|
9 | Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) |
|
Regulation of ventricular cardiac muscle cell membrane depolarization GO:0060373
Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte.
|
9 | Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) Q9NY72 (/IMP) |
Showing 1 to 10 of 43 entries
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Voltage-gated sodium channel complex GO:0001518
A sodium channel in a cell membrane whose opening is governed by the membrane potential.
|
9 | Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) |
|
Voltage-gated sodium channel complex GO:0001518
A sodium channel in a cell membrane whose opening is governed by the membrane potential.
|
9 | Q9NY72 (/TAS) Q9NY72 (/TAS) Q9NY72 (/TAS) Q9NY72 (/TAS) Q9NY72 (/TAS) Q9NY72 (/TAS) Q9NY72 (/TAS) Q9NY72 (/TAS) Q9NY72 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
9 | Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) Q9NY72 (/IDA) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
9 | Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) Q9NY72 (/NAS) |
|
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
|
9 | Q9NY72 (/ISS) Q9NY72 (/ISS) Q9NY72 (/ISS) Q9NY72 (/ISS) Q9NY72 (/ISS) Q9NY72 (/ISS) Q9NY72 (/ISS) Q9NY72 (/ISS) Q9NY72 (/ISS) |
|
Voltage-gated sodium channel complex GO:0001518
A sodium channel in a cell membrane whose opening is governed by the membrane potential.
|
6 | A0A2R8Q4I5 (/IC) A0A2R8QL14 (/IC) F8W5C5 (/IC) Q06W32 (/IC) Q06W34 (/IC) Q06W35 (/IC) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
6 | A0A2R8Q4I5 (/IC) A0A2R8QL14 (/IC) F8W5C5 (/IC) Q06W32 (/IC) Q06W34 (/IC) Q06W35 (/IC) |
|
Voltage-gated sodium channel complex GO:0001518
A sodium channel in a cell membrane whose opening is governed by the membrane potential.
|
2 | Q8BHK2 (/ISO) Q8BHK2 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q8BHK2 (/ISO) Q8BHK2 (/ISO) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q8BHK2 (/ISO) Q8BHK2 (/ISO) |
Showing 1 to 10 of 15 entries
