The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 352: Cell adhesion molecule-related/down-regulated by o...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 A4JYD4 (/IPI) F1QGR0 (/IPI) O35158 (/IPI) Q32MD9 (/IPI) Q4KMG0 (/IPI) Q6AZB0 (/IPI) Q8UVD6 (/IPI) Q9BWV1 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
3 A4JYD4 (/IDA) F1QGR0 (/IDA) Q8UVD6 (/IDA)
Showing 1 to 2 of 2 entries

There are 40 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
4 A4JYD4 (/IMP) F1QGR0 (/IMP) Q6AZB0 (/IMP) Q8UVD6 (/IMP)
Regulation of smoothened signaling pathway GO:0008589
Any process that modulates the frequency, rate or extent of smoothened signaling.
3 A4JYD4 (/IMP) F1QGR0 (/IMP) Q8UVD6 (/IMP)
Retinal ganglion cell axon guidance GO:0031290
The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
3 A4JYD4 (/IMP) F1QGR0 (/IMP) Q8UVD6 (/IMP)
Smoothened signaling pathway GO:0007224
A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
2 O35158 (/IDA) Q6AZB0 (/IDA)
Regulation of striated muscle tissue development GO:0016202
Any process that modulates the frequency, rate or extent of striated muscle development.
2 Q32MD9 (/ISO) Q6AZB0 (/ISO)
Negative regulation of smoothened signaling pathway GO:0045879
Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling.
2 A0A0B5JK41 (/IMP) Q1L8D0 (/IMP)
Positive regulation of muscle cell differentiation GO:0051149
Any process that activates or increases the frequency, rate or extent of muscle cell differentiation.
2 Q4KMG0 (/TAS) Q9BWV1 (/TAS)
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
2 Q32MD9 (/TAS) Q6AZB0 (/TAS)
Cell fate specification GO:0001708
The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
1 Q32MD9 (/IGI)
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
1 Q32MD9 (/IDA)
Showing 1 to 10 of 40 entries

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 Q4KMG0 (/TAS) Q6AZB0 (/TAS) Q9BWV1 (/TAS)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 Q32MD9 (/TAS) Q6AZB0 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q9BWV1 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q6AZB0 (/ISO)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q6AZB0 (/ISA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q32MD9 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 O35158 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q32MD9 (/ISO)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 Q6AZB0 (/IDA)
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
1 Q6AZB0 (/IDA)
Showing 1 to 10 of 13 entries
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