Any process that activates or increases the frequency, rate or extent of phagocytosis.

The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.

The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.

Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.

The movement of a leukocyte within or between different tissues and organs of the body.

Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.

Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.

The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.

The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.

The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

The binding of a cell to the extracellular matrix via adhesion molecules.

The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.

Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.

Any process that activates or increases the rate or extent of cell proliferation.

Any process that stops, prevents or reduces the rate or extent of cell proliferation.

Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.

Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.

The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.

The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.

The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.

Any process that activates or increases the rate or extent of cell adhesion to another cell.

Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.

Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.

Any process that modulates the frequency, rate, or extent of interleukin-1 beta production.

Any process that modulates the frequency, rate, or extent of interleukin-1 beta production.

Any process that modulates the frequency, rate, or extent of interleukin-1 beta production.

Any process that modulates the frequency, rate, or extent of interleukin-6 production.

Any process that modulates the frequency, rate, or extent of interleukin-6 production.

Any process that modulates the frequency, rate, or extent of interleukin-6 production.

Any process that modulates the frequency, rate, or extent of tumor necrosis factor production.

Any process that modulates the frequency, rate, or extent of tumor necrosis factor production.

Any process that modulates the frequency, rate, or extent of tumor necrosis factor production.

Any process that modulates the frequency, rate, or extent of tumor necrosis factor production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.

The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.

The migration of a monocyte from the blood vessels into the surrounding tissue.

The migration of a monocyte from the blood vessels into the surrounding tissue.

The migration of a monocyte from the blood vessels into the surrounding tissue.

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.

Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.

Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.

Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.

Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.

Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.

Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.

Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.

Any process that activates or increases the frequency, rate or extent of T cell activation.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.

Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.

Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.

The movement of a granulocyte within or between different tissues and organs of the body.

Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.

Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.

Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.

Any process that stops, prevents or reduces the frequency, rate or extent of I-kappaB phosphorylation.

Any process that stops, prevents or reduces the frequency, rate or extent of I-kappaB phosphorylation.

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

The external part of the cell wall and/or plasma membrane.

The external part of the cell wall and/or plasma membrane.

The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

The external part of the cell wall and/or plasma membrane.

The external part of the cell wall and/or plasma membrane.

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

The lipid bilayer surrounding a secretory granule.

A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

The lipid bilayer surrounding a tertiary granule.

The lipid bilayer surrounding a ficolin-1-rich granule.