The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1878: Immunoglobulin heavy variable 1-4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P0DOX3 (/IPI)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
2 A8WG82 (/IDA) Q5BJ31 (/IDA)
Monocyte activation GO:0042117
The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
1 P0DOX3 (/IDA)
Positive regulation of interleukin-1 secretion GO:0050716
Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 from a cell.
1 P0DOX3 (/IDA)
Positive regulation of interleukin-1 beta secretion GO:0050718
Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell.
1 P0DOX3 (/IDA)
Positive regulation of tumor necrosis factor secretion GO:1904469
Any process that activates or increases the frequency, rate or extent of tumor necrosis factor secretion.
1 P0DOX3 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P0DOX3 (/IDA)