The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1584: V-set and immunoglobulin domain-containing 4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Complement component C3b binding GO:0001851
Interacting selectively and non-covalently with the C3b product of the complement cascade.
1 Q9Y279 (/IPI)
Complement component C3b binding GO:0001851
Interacting selectively and non-covalently with the C3b product of the complement cascade.
1 F6TUL9 (/ISO)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of interleukin-2 production GO:0032703
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production.
1 F6TUL9 (/IDA)
Negative regulation of T cell proliferation GO:0042130
Any process that stops, prevents or reduces the rate or extent of T cell proliferation.
1 F6TUL9 (/IDA)
Negative regulation of complement activation, alternative pathway GO:0045957
Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway.
1 Q9Y279 (/IPI)
Negative regulation of complement activation, alternative pathway GO:0045957
Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway.
1 F6TUL9 (/ISO)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q9Y279 (/IPI)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 F6TUL9 (/ISO)