The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 1547: Cytokine receptor-like factor 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytokine receptor activity GO:0004896
Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
2 | Q9HC73 (/IDA) Q9HC73 (/IDA) |
|
Cytokine receptor activity GO:0004896
Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
2 | Q9HC73 (/IMP) Q9HC73 (/IMP) |
|
Cytokine receptor activity GO:0004896
Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
1 | Q8CII9 (/ISO) |
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
1 | Q8R4S8 (/IDA) |
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
1 | Q8CII9 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q8CII9 (/IPI) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
1 | Q8R4S8 (/TAS) |
There are 14 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | Q9HC73 (/IDA) Q9HC73 (/IDA) |
|
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | Q9HC73 (/IDA) Q9HC73 (/IDA) |
|
Positive regulation of mast cell activation GO:0033005
Any process that activates or increases the frequency, rate, or extent of mast cell activation.
|
2 | Q9HC73 (/IMP) Q9HC73 (/IMP) |
|
Interleukin-7-mediated signaling pathway GO:0038111
A series of molecular signals initiated by the binding of interleukin-7 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | Q9HC73 (/TAS) Q9HC73 (/TAS) |
|
Positive regulation of receptor signaling pathway via STAT GO:1904894
Any process that activates or increases the frequency, rate or extent of receptor signaling pathway via STAT.
|
2 | Q9HC73 (/IDA) Q9HC73 (/IDA) |
|
Positive regulation of interleukin-5 secretion GO:2000664
Any process that activates or increases the frequency, rate or extent of interleukin-5 secretion.
|
2 | Q9HC73 (/IMP) Q9HC73 (/IMP) |
|
Immunoglobulin secretion involved in immune response GO:0002380
The regulated release of immunoglobulins from a B cell or plasma cell contributing to an immune response.
|
1 | Q8CII9 (/IDA) |
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
1 | Q8CII9 (/IMP) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | Q8CII9 (/ISO) |
|
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q8CII9 (/ISO) |
|
Positive regulation of mast cell activation GO:0033005
Any process that activates or increases the frequency, rate, or extent of mast cell activation.
|
1 | Q8CII9 (/ISO) |
|
T-helper 2 cell cytokine production GO:0035745
Any process that contributes to cytokine production by a T-helper 2 cell.
|
1 | Q8CII9 (/IDA) |
|
Positive regulation of receptor signaling pathway via STAT GO:1904894
Any process that activates or increases the frequency, rate or extent of receptor signaling pathway via STAT.
|
1 | Q8CII9 (/ISO) |
|
Positive regulation of interleukin-5 secretion GO:2000664
Any process that activates or increases the frequency, rate or extent of interleukin-5 secretion.
|
1 | Q8CII9 (/ISO) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q9HC73 (/TAS) Q9HC73 (/TAS) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
1 | Q8CII9 (/IDA) |
