The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1526: Alpha-L-iduronidase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
L-iduronidase activity GO:0003940
Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate.
3 D3ZE16 (/IDA) P35475 (/IDA) P48441 (/IDA)
L-iduronidase activity GO:0003940
Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate.
2 P48441 (/ISS) Q01634 (/ISS)
L-iduronidase activity GO:0003940
Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate.
1 P48441 (/IMP)
L-iduronidase activity GO:0003940
Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate.
1 P48441 (/ISO)
L-iduronidase activity GO:0003940
Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate.
1 P35475 (/TAS)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 D3ZE16 (/IMP)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 P48441 (/ISO)

There are 31 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycosaminoglycan catabolic process GO:0006027
The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.
2 D3ZE16 (/IDA) P48441 (/IDA)
Dermatan sulfate catabolic process GO:0030209
The chemical reactions and pathways resulting in the breakdown of dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.
2 P35475 (/IDA) P48441 (/IDA)
Dermatan sulfate catabolic process GO:0030209
The chemical reactions and pathways resulting in the breakdown of dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.
2 P48441 (/ISS) Q01634 (/ISS)
Heparin catabolic process GO:0030211
The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2 P35475 (/IMP) P48441 (/IMP)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
1 P48441 (/IMP)
Disaccharide metabolic process GO:0005984
The chemical reactions and pathways involving any disaccharide, sugars composed of two monosaccharide units.
1 P35475 (/TAS)
Glycosaminoglycan catabolic process GO:0006027
The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.
1 P48441 (/IMP)
Glycosaminoglycan catabolic process GO:0006027
The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.
1 P48441 (/ISO)
Glycosaminoglycan catabolic process GO:0006027
The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.
1 P35475 (/TAS)
Lysosome organization GO:0007040
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
1 P48441 (/IMP)
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
1 P48441 (/IMP)
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
1 P48441 (/IMP)
Adult walking behavior GO:0007628
The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg.
1 P48441 (/IMP)
Adult locomotory behavior GO:0008344
Locomotory behavior in a fully developed and mature organism.
1 P48441 (/IMP)
Visual learning GO:0008542
Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue.
1 P48441 (/IMP)
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
1 P48441 (/IMP)
Chondroitin sulfate catabolic process GO:0030207
The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
1 P35475 (/TAS)
Dermatan sulfate catabolic process GO:0030209
The chemical reactions and pathways resulting in the breakdown of dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.
1 P48441 (/IMP)
Dermatan sulfate catabolic process GO:0030209
The chemical reactions and pathways resulting in the breakdown of dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.
1 P48441 (/ISO)
Heparin catabolic process GO:0030211
The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
1 P48441 (/IDA)
Heparin catabolic process GO:0030211
The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
1 P48441 (/ISO)
Limb morphogenesis GO:0035108
The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.
1 P48441 (/IMP)
Positive regulation of bone resorption GO:0045780
Any process that activates or increases the frequency, rate or extent of bone resorption.
1 P48441 (/IMP)
Skeletal system morphogenesis GO:0048705
The process in which the anatomical structures of the skeleton are generated and organized.
1 P48441 (/IMP)
Chemical homeostasis GO:0048878
Any biological process involved in the maintenance of an internal steady state of a chemical.
1 P48441 (/IMP)
Bone development GO:0060348
The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.
1 P48441 (/IMP)
Negative regulation of cartilage development GO:0061037
Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
1 P48441 (/IMP)
Negative regulation of secretion of lysosomal enzymes GO:0090341
Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
1 P48441 (/IDA)
Negative regulation of secretion of lysosomal enzymes GO:0090341
Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
1 P48441 (/IMP)
Positive regulation of collagen catabolic process GO:0120158
Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.
1 P48441 (/IMP)
Cartilage homeostasis GO:1990079
A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function.
1 P48441 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P48441 (/IDA)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
1 D3ZE16 (/IDA)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
1 P48441 (/ISO)
Coated vesicle GO:0030135
Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.
1 D3ZE16 (/IDA)
Coated vesicle GO:0030135
Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.
1 P48441 (/ISO)
Lysosomal lumen GO:0043202
The volume enclosed within the lysosomal membrane.
1 P35475 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 P35475 (/HDA)