The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 1092: Sodium channel subunit beta-2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sodium channel regulator activity GO:0017080
Modulates the activity of a sodium channel.
|
3 | O60939 (/IDA) O60939 (/IDA) O60939 (/IDA) |
|
Voltage-gated sodium channel activity involved in cardiac muscle cell action potential GO:0086006
Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
3 | O60939 (/IMP) O60939 (/IMP) O60939 (/IMP) |
|
Voltage-gated sodium channel activity GO:0005248
Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
2 | Q56A07 (/ISO) Q56A07 (/ISO) |
|
Sodium channel regulator activity GO:0017080
Modulates the activity of a sodium channel.
|
2 | Q56A07 (/ISO) Q56A07 (/ISO) |
|
Voltage-gated sodium channel activity involved in cardiac muscle cell action potential GO:0086006
Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
2 | Q56A07 (/ISO) Q56A07 (/ISO) |
|
Voltage-gated sodium channel activity GO:0005248
Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | P54900 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P54900 (/IPI) |
There are 18 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
|
3 | O60939 (/TAS) O60939 (/TAS) O60939 (/TAS) |
|
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
3 | O60939 (/IDA) O60939 (/IDA) O60939 (/IDA) |
|
Cardiac muscle contraction GO:0060048
Muscle contraction of cardiac muscle tissue.
|
3 | O60939 (/IMP) O60939 (/IMP) O60939 (/IMP) |
|
Regulation of atrial cardiac muscle cell membrane depolarization GO:0060371
Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte.
|
3 | O60939 (/IMP) O60939 (/IMP) O60939 (/IMP) |
|
Cardiac muscle cell action potential involved in contraction GO:0086002
An action potential that occurs in a cardiac muscle cell and is involved in its contraction.
|
3 | O60939 (/IMP) O60939 (/IMP) O60939 (/IMP) |
|
Membrane depolarization during cardiac muscle cell action potential GO:0086012
The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
|
3 | O60939 (/IMP) O60939 (/IMP) O60939 (/IMP) |
|
Regulation of heart rate by cardiac conduction GO:0086091
A cardiac conduction process that modulates the frequency or rate of heart contraction.
|
3 | O60939 (/IMP) O60939 (/IMP) O60939 (/IMP) |
|
Regulation of sodium ion transmembrane transporter activity GO:2000649
Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity.
|
3 | O60939 (/IDA) O60939 (/IDA) O60939 (/IDA) |
|
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
2 | Q56A07 (/ISO) Q56A07 (/ISO) |
|
Response to pyrethroid GO:0046684
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrethroid stimulus. Pyrethroids are a group of growth regulators, analogous to insect juvenile hormones, that interfere with the development of insect larvae and are used in the control of insects that are harmful in the adult stage.
|
2 | Q56A07 (/ISO) Q56A07 (/ISO) |
|
Cardiac muscle contraction GO:0060048
Muscle contraction of cardiac muscle tissue.
|
2 | Q56A07 (/ISO) Q56A07 (/ISO) |
|
Regulation of atrial cardiac muscle cell membrane depolarization GO:0060371
Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte.
|
2 | Q56A07 (/ISO) Q56A07 (/ISO) |
|
Cardiac muscle cell action potential involved in contraction GO:0086002
An action potential that occurs in a cardiac muscle cell and is involved in its contraction.
|
2 | Q56A07 (/ISO) Q56A07 (/ISO) |
|
Membrane depolarization during cardiac muscle cell action potential GO:0086012
The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
|
2 | Q56A07 (/ISO) Q56A07 (/ISO) |
|
Regulation of heart rate by cardiac conduction GO:0086091
A cardiac conduction process that modulates the frequency or rate of heart contraction.
|
2 | Q56A07 (/ISO) Q56A07 (/ISO) |
|
Regulation of sodium ion transmembrane transporter activity GO:2000649
Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity.
|
2 | Q56A07 (/ISO) Q56A07 (/ISO) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
1 | P54900 (/IEP) |
|
Response to pyrethroid GO:0046684
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrethroid stimulus. Pyrethroids are a group of growth regulators, analogous to insect juvenile hormones, that interfere with the development of insect larvae and are used in the control of insects that are harmful in the adult stage.
|
1 | P54900 (/IDA) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Voltage-gated sodium channel complex GO:0001518
A sodium channel in a cell membrane whose opening is governed by the membrane potential.
|
4 | O60939 (/TAS) O60939 (/TAS) O60939 (/TAS) P54900 (/TAS) |
|
Voltage-gated sodium channel complex GO:0001518
A sodium channel in a cell membrane whose opening is governed by the membrane potential.
|
3 | O60939 (/IDA) O60939 (/IDA) O60939 (/IDA) |
|
Voltage-gated sodium channel complex GO:0001518
A sodium channel in a cell membrane whose opening is governed by the membrane potential.
|
2 | Q56A07 (/ISO) Q56A07 (/ISO) |
