The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 1086: Cell surface glycoprotein MUC18
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
4 | G1MUE6 (/ISS) G3US47 (/ISS) Q98921 (/ISS) Q98922 (/ISS) |
Extracellular matrix binding GO:0050840
Interacting selectively and non-covalently with a component of the extracellular matrix.
|
4 | G1MUE6 (/ISS) G3US47 (/ISS) Q98921 (/ISS) Q98922 (/ISS) |
Cell adhesion mediator activity GO:0098631
The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell.
|
4 | G1MUE6 (/ISS) G3US47 (/ISS) Q98921 (/ISS) Q98922 (/ISS) |
Cell-cell adhesion mediator activity GO:0098632
The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell.
|
4 | G1MUE6 (/ISS) G3US47 (/ISS) Q98921 (/ISS) Q98922 (/ISS) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | Q90880 (/IDA) Q90989 (/IDA) |
Extracellular matrix binding GO:0050840
Interacting selectively and non-covalently with a component of the extracellular matrix.
|
2 | Q90880 (/IMP) Q90989 (/IMP) |
Cell adhesion mediator activity GO:0098631
The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell.
|
2 | Q90880 (/IDA) Q90989 (/IDA) |
Cell-cell adhesion mediator activity GO:0098632
The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell.
|
2 | Q90880 (/IDA) Q90989 (/IDA) |
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
|
4 | G1MUE6 (/ISS) G3US47 (/ISS) Q98921 (/ISS) Q98922 (/ISS) |
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
4 | G1MUE6 (/ISS) G3US47 (/ISS) Q98921 (/ISS) Q98922 (/ISS) |
Cell-cell adhesion via plasma-membrane adhesion molecules GO:0098742
The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane.
|
4 | G1MUE6 (/ISS) G3US47 (/ISS) Q98921 (/ISS) Q98922 (/ISS) |
Cell aggregation GO:0098743
The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.
|
4 | G1MUE6 (/ISS) G3US47 (/ISS) Q98921 (/ISS) Q98922 (/ISS) |
Epithelium regeneration GO:1990399
The regrowth of lost or destroyed epithelium.
|
4 | G1MUE6 (/ISS) G3US47 (/ISS) Q98921 (/ISS) Q98922 (/ISS) |
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
2 | P43121 (/IDA) P43121 (/IDA) |
Glomerular filtration GO:0003094
The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein.
|
2 | P43121 (/IEP) P43121 (/IEP) |
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
2 | P43121 (/TAS) P43121 (/TAS) |
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
|
2 | Q90880 (/IDA) Q90989 (/IDA) |
Anatomical structure morphogenesis GO:0009653
The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
|
2 | P43121 (/TAS) P43121 (/TAS) |
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
2 | Q90880 (/IDA) Q90989 (/IDA) |
Vascular wound healing GO:0061042
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
|
2 | P43121 (/IEP) P43121 (/IEP) |
Cell-cell adhesion via plasma-membrane adhesion molecules GO:0098742
The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane.
|
2 | Q90880 (/IMP) Q90989 (/IMP) |
Cell aggregation GO:0098743
The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.
|
2 | Q90880 (/IDA) Q90989 (/IDA) |
Epithelium regeneration GO:1990399
The regrowth of lost or destroyed epithelium.
|
2 | Q90880 (/IMP) Q90989 (/IMP) |
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
1 | Q8R2Y2 (/ISO) |
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
1 | Q8R2Y2 (/ISO) |
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
|
1 | Q8R2Y2 (/ISO) |
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
1 | Q9EPF2 (/IDA) |
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
1 | Q8R2Y2 (/ISO) |
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | G1MUE6 (/ISS) G3US47 (/ISS) Q98921 (/ISS) Q98922 (/ISS) |
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
4 | G1MUE6 (/ISS) G3US47 (/ISS) Q98921 (/ISS) Q98922 (/ISS) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | P43121 (/HDA) P43121 (/HDA) |
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
|
2 | Q90880 (/IDA) Q90989 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q90880 (/IDA) Q90989 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | P43121 (/NAS) P43121 (/NAS) |
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
2 | P43121 (/HDA) P43121 (/HDA) |
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
2 | P43121 (/IDA) P43121 (/IDA) |
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
2 | Q90880 (/IDA) Q90989 (/IDA) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q9EPF2 (/IDA) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q8R2Y2 (/ISO) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9EPF2 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q8R2Y2 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q8R2Y2 (/ISO) |
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
1 | Q8R2Y2 (/ISO) |