The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 1077: T-lymphocyte activation antigen CD80
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | P33681 (/IPI) P33681 (/IPI) Q00609 (/IPI) Q00609 (/IPI) |
|
Coreceptor activity GO:0015026
Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.
|
2 | P33681 (/NAS) P33681 (/NAS) |
There are 18 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
|
4 | O77684 (/ISS) Q28347 (/ISS) Q28499 (/ISS) Q9BDN6 (/ISS) |
|
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
|
3 | A0A0G2K0F2 (/IMP) G3V671 (/IMP) O35187 (/IMP) |
|
Positive regulation of signal transduction GO:0009967
Any process that activates or increases the frequency, rate or extent of signal transduction.
|
2 | P33681 (/NAS) P33681 (/NAS) |
|
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | P33681 (/TAS) P33681 (/TAS) |
|
T cell costimulation GO:0031295
The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.
|
2 | Q00609 (/IDA) Q00609 (/IDA) |
|
T cell costimulation GO:0031295
The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.
|
2 | P33681 (/TAS) P33681 (/TAS) |
|
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
|
2 | P33681 (/NAS) P33681 (/NAS) |
|
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
|
2 | Q00609 (/IGI) Q00609 (/IGI) |
|
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
|
2 | Q00609 (/ISO) Q00609 (/ISO) |
|
Positive regulation of interleukin-2 biosynthetic process GO:0045086
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2.
|
2 | P33681 (/NAS) P33681 (/NAS) |
|
Positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process GO:0045425
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor.
|
2 | P33681 (/NAS) P33681 (/NAS) |
|
Positive regulation of T-helper 1 cell differentiation GO:0045627
Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation.
|
2 | P33681 (/NAS) P33681 (/NAS) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P33681 (/NAS) P33681 (/NAS) |
|
Positive regulation of alpha-beta T cell proliferation GO:0046641
Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation.
|
2 | Q00609 (/IDA) Q00609 (/IDA) |
|
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
|
2 | P33681 (/IDA) P33681 (/IDA) |
|
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
|
2 | Q00609 (/ISO) Q00609 (/ISO) |
|
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
2 | P33681 (/TAS) P33681 (/TAS) |
|
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
2 | Q00609 (/IDA) Q00609 (/IDA) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
3 | A0A0G2K0F2 (/IDA) G3V671 (/IDA) O35187 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | P33681 (/NAS) P33681 (/NAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | P33681 (/TAS) P33681 (/TAS) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
2 | Q00609 (/IDA) Q00609 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | P33681 (/HDA) P33681 (/HDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | Q00609 (/ISO) Q00609 (/ISO) |
|
Protein complex involved in cell adhesion GO:0098636
Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell.
|
2 | P33681 (/IDA) P33681 (/IDA) |
|
Protein complex involved in cell adhesion GO:0098636
Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell.
|
2 | Q00609 (/ISO) Q00609 (/ISO) |