The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Urease metallochaperone UreE, N-terminal domain
".
FunFam 7: dnaJ homolog subfamily B member 5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 18 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
26 |
O75953 (/IPI)
O75953 (/IPI)
O75953 (/IPI)
O75953 (/IPI)
O75953 (/IPI)
O75953 (/IPI)
O75953 (/IPI)
O75953 (/IPI)
O75953 (/IPI)
O89114 (/IPI)
(16 more) |
|
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
|
24 |
O75953 (/IPI)
O75953 (/IPI)
O75953 (/IPI)
O75953 (/IPI)
O75953 (/IPI)
O75953 (/IPI)
O75953 (/IPI)
O75953 (/IPI)
O75953 (/IPI)
P25685 (/IPI)
(14 more) |
|
ATPase activator activity GO:0001671
Binds to and increases the ATP hydrolysis activity of an ATPase.
|
15 |
P25685 (/IDA)
P25685 (/IDA)
P25685 (/IDA)
P25685 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
(5 more) |
|
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
|
11 |
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
(1 more) |
|
ATPase activator activity GO:0001671
Binds to and increases the ATP hydrolysis activity of an ATPase.
|
8 | Q2KIT4 (/ISS) Q3MI00 (/ISS) Q3MI00 (/ISS) Q3MI00 (/ISS) Q5R8J8 (/ISS) Q9D832 (/ISS) Q9QYJ3 (/ISS) Q9QYJ3 (/ISS) |
|
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
|
5 | Q3MI00 (/ISS) Q3MI00 (/ISS) Q3MI00 (/ISS) Q9QYJ3 (/ISS) Q9QYJ3 (/ISS) |
|
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
|
5 | O89114 (/ISO) O89114 (/ISO) Q9D832 (/ISO) Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
|
4 | P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) |
|
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
|
4 | P25685 (/IPI) P25685 (/IPI) P25685 (/IPI) P25685 (/IPI) |
|
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
|
4 | P25685 (/HDA) P25685 (/HDA) P25685 (/HDA) P25685 (/HDA) |
|
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
|
4 | P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) |
|
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
|
4 | P25685 (/IPI) P25685 (/IPI) P25685 (/IPI) P25685 (/IPI) |
|
ATPase activator activity GO:0001671
Binds to and increases the ATP hydrolysis activity of an ATPase.
|
3 | Q9D832 (/ISO) Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
|
2 | O89114 (/ISS) O89114 (/ISS) |
|
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Response to unfolded protein GO:0006986
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
|
15 |
P25685 (/TAS)
P25685 (/TAS)
P25685 (/TAS)
P25685 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
(5 more) |
|
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
11 |
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
Q9UDY4 (/TAS)
(1 more) |
|
Response to unfolded protein GO:0006986
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
|
9 | O75953 (/IEP) O75953 (/IEP) O75953 (/IEP) O75953 (/IEP) O75953 (/IEP) O75953 (/IEP) O75953 (/IEP) O75953 (/IEP) O75953 (/IEP) |
|
Negative regulation of transcription from RNA polymerase II promoter in response to stress GO:0097201
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
|
5 | Q3MI00 (/ISS) Q3MI00 (/ISS) Q3MI00 (/ISS) Q9QYJ3 (/ISS) Q9QYJ3 (/ISS) |
|
Lens development in camera-type eye GO:0002088
The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
|
4 | A0A0R4IYH3 (/IMP) B8JM56 (/IMP) Q6DEJ4 (/IMP) Q7ZVY8 (/IMP) |
|
Positive regulation of ATPase activity GO:0032781
Any process that activates or increases the rate of ATP hydrolysis by an ATPase.
|
4 | P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) |
|
Chaperone cofactor-dependent protein refolding GO:0051085
The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release.
|
4 | P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) |
|
Negative regulation of inclusion body assembly GO:0090084
Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
|
4 | P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) |
|
Negative regulation of transcription from RNA polymerase II promoter in response to stress GO:0097201
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
|
4 | P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) |
|
Regulation of cellular response to heat GO:1900034
Any process that modulates the frequency, rate or extent of cellular response to heat.
|
4 | P25685 (/TAS) P25685 (/TAS) P25685 (/TAS) P25685 (/TAS) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | O89114 (/IGI) O89114 (/IGI) |
|
Positive regulation of ATPase activity GO:0032781
Any process that activates or increases the rate of ATP hydrolysis by an ATPase.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Chaperone cofactor-dependent protein refolding GO:0051085
The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release.
|
2 | Q9QYJ3 (/IGI) Q9QYJ3 (/IGI) |
|
Chaperone cofactor-dependent protein refolding GO:0051085
The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Negative regulation of inclusion body assembly GO:0090084
Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Negative regulation of transcription from RNA polymerase II promoter in response to stress GO:0097201
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Forebrain development GO:0030900
The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
|
1 | B0K030 (/IEP) |
There are 28 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
26 |
O75953 (/IDA)
O75953 (/IDA)
O75953 (/IDA)
O75953 (/IDA)
O75953 (/IDA)
O75953 (/IDA)
O75953 (/IDA)
O75953 (/IDA)
O75953 (/IDA)
O89114 (/IDA)
(16 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
11 |
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
(1 more) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
11 |
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
Q9UDY4 (/IDA)
(1 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
10 | O89114 (/IDA) O89114 (/IDA) P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) Q6FHS4 (/IDA) Q6FHS4 (/IDA) Q6FHS4 (/IDA) Q6FHS4 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | O89114 (/ISO) O89114 (/ISO) Q9D832 (/ISO) Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | P25685 (/HDA) P25685 (/HDA) P25685 (/HDA) P25685 (/HDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
4 | P25685 (/TAS) P25685 (/TAS) P25685 (/TAS) P25685 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) P25685 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | P25685 (/TAS) P25685 (/TAS) P25685 (/TAS) P25685 (/TAS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
4 | P25685 (/HDA) P25685 (/HDA) P25685 (/HDA) P25685 (/HDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Sperm head GO:0061827
The part of the late spermatid or spermatozoon that contains the nucleus and acrosome.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Postsynapse GO:0098794
The part of a synapse that is part of the post-synaptic cell.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Postsynaptic cytosol GO:0099524
The region of the cytosol consisting of all cytosol that is part of the postsynapse.
|
2 | Q9QYJ3 (/ISO) Q9QYJ3 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9D832 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9D832 (/ISO) |
|
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
|
1 | B0K030 (/IDA) |
|
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | B0K030 (/IDA) |
|
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
|
1 | B0K030 (/IDA) |
|
Sperm head GO:0061827
The part of the late spermatid or spermatozoon that contains the nucleus and acrosome.
|
1 | B0K030 (/IDA) |
|
Postsynapse GO:0098794
The part of a synapse that is part of the post-synaptic cell.
|
1 | B0K030 (/IDA) |
|
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
|
1 | B0K030 (/IDA) |
|
Postsynaptic cytosol GO:0099524
The region of the cytosol consisting of all cytosol that is part of the postsynapse.
|
1 | B0K030 (/IDA) |
