The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Urease metallochaperone UreE, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15: Heat shock protein 40

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
13 Q8I2E1 (/ISS) Q8I2E1 (/ISS) Q8I489 (/ISS) Q8I489 (/ISS) Q8I489 (/ISS) Q8I489 (/ISS) Q8I489 (/ISS) Q8I489 (/ISS) Q8I489 (/ISS) Q8I489 (/ISS)
(3 more)
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
10 O76224 (/ISM) O76224 (/ISM) O76224 (/ISM) O76224 (/ISM) O76224 (/ISM) Q38AB7 (/ISM) Q38AB7 (/ISM) Q38AB7 (/ISM) Q38AB7 (/ISM) Q38AB7 (/ISM)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
11 O96212 (/ISS) O96212 (/ISS) O96212 (/ISS) O96212 (/ISS) O96212 (/ISS) O96212 (/ISS) O96212 (/ISS) O96212 (/ISS) O96212 (/ISS) O96212 (/ISS)
(1 more)
Response to unfolded protein GO:0006986
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
11 O96212 (/ISS) O96212 (/ISS) O96212 (/ISS) O96212 (/ISS) O96212 (/ISS) O96212 (/ISS) O96212 (/ISS) O96212 (/ISS) O96212 (/ISS) O96212 (/ISS)
(1 more)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
11 O96212 (/IDA) O96212 (/IDA) O96212 (/IDA) O96212 (/IDA) O96212 (/IDA) O96212 (/IDA) O96212 (/IDA) O96212 (/IDA) O96212 (/IDA) O96212 (/IDA)
(1 more)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
10 O76224 (/ISM) O76224 (/ISM) O76224 (/ISM) O76224 (/ISM) O76224 (/ISM) Q38AB7 (/ISM) Q38AB7 (/ISM) Q38AB7 (/ISM) Q38AB7 (/ISM) Q38AB7 (/ISM)
Response to unfolded protein GO:0006986
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
10 O76224 (/ISA) O76224 (/ISA) O76224 (/ISA) O76224 (/ISA) O76224 (/ISA) Q38AB7 (/ISA) Q38AB7 (/ISA) Q38AB7 (/ISA) Q38AB7 (/ISA) Q38AB7 (/ISA)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
10 O76224 (/IEP) O76224 (/IEP) O76224 (/IEP) O76224 (/IEP) O76224 (/IEP) Q38AB7 (/IEP) Q38AB7 (/IEP) Q38AB7 (/IEP) Q38AB7 (/IEP) Q38AB7 (/IEP)
Posttranscriptional regulation of gene expression GO:0010608
Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
10 O76224 (/IDA) O76224 (/IDA) O76224 (/IDA) O76224 (/IDA) O76224 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA)
Protein refolding GO:0042026
The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
10 O76224 (/ISA) O76224 (/ISA) O76224 (/ISA) O76224 (/ISA) O76224 (/ISA) Q38AB7 (/ISA) Q38AB7 (/ISA) Q38AB7 (/ISA) Q38AB7 (/ISA) Q38AB7 (/ISA)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
2 Q8I2E1 (/ISS) Q8I2E1 (/ISS)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Host cell cytosol GO:0044164
The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
13 Q8I2E1 (/IDA) Q8I2E1 (/IDA) Q8I489 (/IDA) Q8I489 (/IDA) Q8I489 (/IDA) Q8I489 (/IDA) Q8I489 (/IDA) Q8I489 (/IDA) Q8I489 (/IDA) Q8I489 (/IDA)
(3 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
11 O96212 (/IDA) O96212 (/IDA) O96212 (/IDA) O96212 (/IDA) O96212 (/IDA) O96212 (/IDA) O96212 (/IDA) O96212 (/IDA) O96212 (/IDA) O96212 (/IDA)
(1 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
10 O76224 (/IDA) O76224 (/IDA) O76224 (/IDA) O76224 (/IDA) O76224 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
10 O76224 (/IDA) O76224 (/IDA) O76224 (/IDA) O76224 (/IDA) O76224 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
10 O76224 (/IDA) O76224 (/IDA) O76224 (/IDA) O76224 (/IDA) O76224 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA) Q38AB7 (/IDA)
Infected host cell surface knob GO:0020030
Protrusion that develops in the plasma membrane of a parasitized erythrocyte. An example of this component is found in Plasmodium species.
4 O96123 (/IDA) O96123 (/IDA) O96123 (/IDA) O96123 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q4Q0D3 (/ISO)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
1 Q4Q0D3 (/ISO)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 Q4Q0D3 (/ISO)
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