The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Transforming growth factor beta

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 36 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Type II transforming growth factor beta receptor binding GO:0005114
Interacting selectively and non-covalently with a type II transforming growth factor beta receptor.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Transforming growth factor beta receptor binding GO:0005160
Interacting selectively and non-covalently with the transforming growth factor beta receptor.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Type III transforming growth factor beta receptor binding GO:0034714
Interacting selectively and non-covalently with a type III transforming growth factor beta receptor.
147 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(137 more)
Type II transforming growth factor beta receptor binding GO:0005114
Interacting selectively and non-covalently with a type II transforming growth factor beta receptor.
15 B2R7T2 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP)
(5 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
15 P27090 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI)
(5 more)
Type III transforming growth factor beta receptor binding GO:0034714
Interacting selectively and non-covalently with a type III transforming growth factor beta receptor.
15 B2R7T2 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP)
(5 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
15 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(5 more)
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
14 P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP)
(4 more)
Type II transforming growth factor beta receptor binding GO:0005114
Interacting selectively and non-covalently with a type II transforming growth factor beta receptor.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Type II transforming growth factor beta receptor binding GO:0005114
Interacting selectively and non-covalently with a type II transforming growth factor beta receptor.
14 P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI)
(4 more)
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
14 P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS)
(4 more)
Transforming growth factor beta receptor binding GO:0005160
Interacting selectively and non-covalently with the transforming growth factor beta receptor.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Type III transforming growth factor beta receptor binding GO:0034714
Interacting selectively and non-covalently with a type III transforming growth factor beta receptor.
14 P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI) P61812 (/IPI)
(4 more)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
14 P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS)
(4 more)
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
1 P30371 (/ISA)
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
1 P27090 (/ISO)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 P30371 (/ISA)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 P27090 (/ISO)
Type II transforming growth factor beta receptor binding GO:0005114
Interacting selectively and non-covalently with a type II transforming growth factor beta receptor.
1 P30371 (/ISA)
Type II transforming growth factor beta receptor binding GO:0005114
Interacting selectively and non-covalently with a type II transforming growth factor beta receptor.
1 P27090 (/ISO)
Transforming growth factor beta receptor binding GO:0005160
Interacting selectively and non-covalently with the transforming growth factor beta receptor.
1 P30371 (/ISA)
Transforming growth factor beta receptor binding GO:0005160
Interacting selectively and non-covalently with the transforming growth factor beta receptor.
1 P27090 (/ISO)
Transforming growth factor beta receptor binding GO:0005160
Interacting selectively and non-covalently with the transforming growth factor beta receptor.
1 Q07257 (/TAS)
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
1 P27090 (/TAS)
Type III transforming growth factor beta receptor binding GO:0034714
Interacting selectively and non-covalently with a type III transforming growth factor beta receptor.
1 P30371 (/ISA)
Type III transforming growth factor beta receptor binding GO:0034714
Interacting selectively and non-covalently with a type III transforming growth factor beta receptor.
1 P27090 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P30371 (/ISA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P27090 (/ISO)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 Q07257 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 P27090 (/ISO)
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 Q07257 (/IMP)
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 P27090 (/ISO)

There are 372 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Cell death GO:0008219
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Glial cell migration GO:0008347
The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Cardioblast differentiation GO:0010002
The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Positive regulation of epithelial cell migration GO:0010634
Any process that activates or increases the frequency, rate or extent of epithelial cell migration.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Negative regulation of alkaline phosphatase activity GO:0010693
Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Positive regulation of epithelial to mesenchymal transition GO:0010718
Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Negative regulation of macrophage cytokine production GO:0010936
Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Collagen fibril organization GO:0030199
Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Activation of protein kinase activity GO:0032147
Any process that initiates the activity of an inactive protein kinase.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Positive regulation of stress-activated MAPK cascade GO:0032874
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Regulation of transforming growth factor beta2 production GO:0032909
Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Positive regulation of cell adhesion mediated by integrin GO:0033630
Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Cell-cell junction organization GO:0045216
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Positive regulation of integrin biosynthetic process GO:0045726
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Positive regulation of heart contraction GO:0045823
Any process that activates or increases the frequency, rate or extent of heart contraction.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Positive regulation of protein secretion GO:0050714
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Positive regulation of timing of catagen GO:0051795
Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Positive regulation of cardioblast differentiation GO:0051891
Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Cardiac muscle cell proliferation GO:0060038
The expansion of a cardiac muscle cell population by cell division.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Cardiac epithelial to mesenchymal transition GO:0060317
A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Salivary gland morphogenesis GO:0007435
The process in which the anatomical structures of the salivary gland are generated and organized.
147 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(137 more)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
147 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(137 more)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
147 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(137 more)
Positive regulation of ossification GO:0045778
Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
147 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(137 more)
Embryonic digestive tract development GO:0048566
The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus.
147 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(137 more)
Pathway-restricted SMAD protein phosphorylation GO:0060389
The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor.
147 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(137 more)
Extrinsic apoptotic signaling pathway GO:0097191
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.
147 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(137 more)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
146 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(136 more)
SMAD protein signal transduction GO:0060395
The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell.
139 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A8RRQ5 (/ISS)
(129 more)
Hair follicle development GO:0001942
The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.
136 D2HL87 (/ISS) D2HL87 (/ISS) D2HL87 (/ISS) F1PKH0 (/ISS) F1PKH0 (/ISS) F1PKH0 (/ISS) F1PKH0 (/ISS) F1PKH0 (/ISS) F1PKH2 (/ISS) F1PKH2 (/ISS)
(126 more)
Signal transduction by protein phosphorylation GO:0023014
A process in which the transfer of one or more phosphate groups to a substrate transmits a signal to the phosphorylated substrate.
129 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(119 more)
Hemopoiesis GO:0030097
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
32 P09858 (/ISS) P30371 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS)
(22 more)
Neutrophil chemotaxis GO:0030593
The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
32 P27090 (/ISS) P30371 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS)
(22 more)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
32 P09858 (/ISS) P27090 (/ISS) P30371 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS)
(22 more)
Dopamine biosynthetic process GO:0042416
The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
32 P09858 (/ISS) P30371 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS)
(22 more)
Positive regulation of cell cycle GO:0045787
Any process that activates or increases the rate or extent of progression through the cell cycle.
32 P09858 (/ISS) P30371 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS)
(22 more)
Somatic stem cell division GO:0048103
The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.
32 P09858 (/ISS) P30371 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS)
(22 more)
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
32 P09858 (/ISS) P30371 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS)
(22 more)
Positive regulation of immune response GO:0050778
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
32 P27090 (/ISS) P30371 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS)
(22 more)
Hair follicle morphogenesis GO:0031069
The process in which the anatomical structures of the hair follicle are generated and organized.
31 P09858 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS)
(21 more)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
19 P09858 (/ISS) P27090 (/ISS) P30371 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS)
(9 more)
Regulation of timing of catagen GO:0051794
Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.
18 P09858 (/ISS) P27090 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS)
(8 more)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
15 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(5 more)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
15 P27090 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(5 more)
Embryonic digestive tract development GO:0048566
The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus.
15 P30371 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP)
(5 more)
Pathway-restricted SMAD protein phosphorylation GO:0060389
The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor.
15 P27090 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(5 more)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
14 P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS)
(4 more)
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
14 P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP)
(4 more)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
14 P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS)
(4 more)
Neural tube closure GO:0001843
The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Hair follicle development GO:0001942
The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Platelet degranulation GO:0002576
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
14 P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS)
(4 more)
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Outflow tract septum morphogenesis GO:0003148
The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Membranous septum morphogenesis GO:0003149
The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Heart valve morphogenesis GO:0003179
The process in which the structure of a heart valve is generated and organized.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Atrioventricular valve morphogenesis GO:0003181
The process in which the structure of the atrioventricular valve is generated and organized.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Pulmonary valve morphogenesis GO:0003184
The process in which the structure of the pulmonary valve is generated and organized.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Endocardial cushion morphogenesis GO:0003203
The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Cardiac right ventricle morphogenesis GO:0003215
The process in which the right cardiac ventricle is generated and organized.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Ventricular trabecula myocardium morphogenesis GO:0003222
The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Endocardial cushion fusion GO:0003274
The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Atrial septum primum morphogenesis GO:0003289
The process in which anatomical structure of an atrial septum primum is generated and organized.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Neural retina development GO:0003407
The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Salivary gland morphogenesis GO:0007435
The process in which the anatomical structures of the salivary gland are generated and organized.
14 P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP)
(4 more)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Cell death GO:0008219
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Glial cell migration GO:0008347
The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
14 P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP)
(4 more)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
14 P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS)
(4 more)
Cardioblast differentiation GO:0010002
The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Positive regulation of epithelial cell migration GO:0010634
Any process that activates or increases the frequency, rate or extent of epithelial cell migration.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Negative regulation of alkaline phosphatase activity GO:0010693
Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Positive regulation of epithelial to mesenchymal transition GO:0010718
Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Negative regulation of macrophage cytokine production GO:0010936
Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Collagen fibril organization GO:0030199
Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Embryonic limb morphogenesis GO:0030326
The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Neutrophil chemotaxis GO:0030593
The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
14 P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS)
(4 more)
Activation of protein kinase activity GO:0032147
Any process that initiates the activity of an inactive protein kinase.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Positive regulation of stress-activated MAPK cascade GO:0032874
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Regulation of transforming growth factor beta2 production GO:0032909
Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2.
14 P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP)
(4 more)
Positive regulation of cell adhesion mediated by integrin GO:0033630
Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Ascending aorta morphogenesis GO:0035910
The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Odontogenesis GO:0042476
The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
14 P61812 (/NAS) P61812 (/NAS) P61812 (/NAS) P61812 (/NAS) P61812 (/NAS) P61812 (/NAS) P61812 (/NAS) P61812 (/NAS) P61812 (/NAS) P61812 (/NAS)
(4 more)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Uterine wall breakdown GO:0042704
The sloughing of the endometrium and blood vessels during menstruation that results from a drop in progesterone levels.
14 P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS)
(4 more)
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Cell-cell junction organization GO:0045216
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Positive regulation of integrin biosynthetic process GO:0045726
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Positive regulation of Notch signaling pathway GO:0045747
Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Positive regulation of ossification GO:0045778
Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
14 P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP) P61812 (/IEP)
(4 more)
Positive regulation of heart contraction GO:0045823
Any process that activates or increases the frequency, rate or extent of heart contraction.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Negative regulation of Ras protein signal transduction GO:0046580
Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Generation of neurons GO:0048699
The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.
14 P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS)
(4 more)
Inner ear development GO:0048839
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
14 P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP) P61812 (/IMP)
(4 more)
Positive regulation of protein secretion GO:0050714
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Negative regulation of immune response GO:0050777
Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
14 P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS)
(4 more)
Regulation of timing of catagen GO:0051794
Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Positive regulation of timing of catagen GO:0051795
Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Positive regulation of cardioblast differentiation GO:0051891
Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Cardiac muscle cell proliferation GO:0060038
The expansion of a cardiac muscle cell population by cell division.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Uterus development GO:0060065
The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Cardiac epithelial to mesenchymal transition GO:0060317
A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
SMAD protein signal transduction GO:0060395
The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Ventricular septum morphogenesis GO:0060412
The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Atrial septum morphogenesis GO:0060413
The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Pharyngeal arch artery morphogenesis GO:0061626
The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Secondary palate development GO:0062009
The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Extrinsic apoptotic signaling pathway GO:0097191
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256
Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895
Any process that activates or increases the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Substantia propria of cornea development GO:1903701
The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Cranial skeletal system development GO:1904888
The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation GO:1905006
Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation GO:1905007
Any process that activates or increases the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.
14 P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS) P61812 (/ISS)
(4 more)
Skeletal muscle tissue development GO:0007519
The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
2 P30371 (/IEP) Q07257 (/IEP)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
2 P30371 (/TAS) Q07257 (/TAS)
Hard palate development GO:0060022
The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes.
2 F8W4A6 (/IMP) Q7SZV4 (/IMP)
Sclerotome development GO:0061056
The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.
2 F8W4A6 (/IMP) Q7SZV4 (/IMP)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
1 P30371 (/ISA)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
1 P27090 (/ISO)
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
1 P27090 (/IMP)
Cartilage condensation GO:0001502
The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes.
1 P27090 (/IGI)
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
1 Q07257 (/TAS)
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
1 P27090 (/IMP)
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
1 P30371 (/IEP)
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
1 P30371 (/ISA)
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
1 P27090 (/ISO)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 P30371 (/ISA)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 P27090 (/ISO)
Mesoderm formation GO:0001707
The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
1 P09858 (/TAS)
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
1 P30371 (/IEP)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
1 Q07257 (/IEP)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
1 P27090 (/IMP)
Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
1 P30371 (/ISA)
Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
1 P27090 (/ISO)
Neural tube closure GO:0001843
The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.
1 P27090 (/IMP)
Hair follicle development GO:0001942
The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.
1 P27090 (/IMP)
Hair follicle development GO:0001942
The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.
1 P27090 (/ISO)
Blood vessel remodeling GO:0001974
The reorganization or renovation of existing blood vessels.
1 P27090 (/IMP)
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 P30371 (/ISA)
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 P27090 (/ISO)
Outflow tract septum morphogenesis GO:0003148
The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.
1 P27090 (/IMP)
Membranous septum morphogenesis GO:0003149
The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum.
1 P27090 (/IMP)
Outflow tract morphogenesis GO:0003151
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
1 P27090 (/TAS)
Heart valve morphogenesis GO:0003179
The process in which the structure of a heart valve is generated and organized.
1 P27090 (/IMP)
Atrioventricular valve morphogenesis GO:0003181
The process in which the structure of the atrioventricular valve is generated and organized.
1 P27090 (/IMP)
Pulmonary valve morphogenesis GO:0003184
The process in which the structure of the pulmonary valve is generated and organized.
1 P27090 (/IMP)
Epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198
A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion.
1 P30371 (/TAS)
Endocardial cushion morphogenesis GO:0003203
The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
1 P27090 (/IMP)
Cardiac left ventricle morphogenesis GO:0003214
The process in which the left cardiac ventricle is generated and organized.
1 P27090 (/TAS)
Cardiac right ventricle morphogenesis GO:0003215
The process in which the right cardiac ventricle is generated and organized.
1 P27090 (/IMP)
Cardiac right ventricle morphogenesis GO:0003215
The process in which the right cardiac ventricle is generated and organized.
1 P27090 (/TAS)
Ventricular trabecula myocardium morphogenesis GO:0003222
The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized.
1 P27090 (/IMP)
Endocardial cushion fusion GO:0003274
The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping.
1 P27090 (/IMP)
Atrial septum primum morphogenesis GO:0003289
The process in which anatomical structure of an atrial septum primum is generated and organized.
1 P27090 (/IMP)
Neural retina development GO:0003407
The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
1 P27090 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 P30371 (/ISA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 P27090 (/ISO)
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
1 P30371 (/ISA)
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
1 P27090 (/ISO)
Negative regulation of cell adhesion GO:0007162
Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
1 P30371 (/TAS)
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 P30371 (/ISA)
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 P27090 (/ISO)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
1 P30371 (/TAS)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
1 P27090 (/IMP)
Salivary gland morphogenesis GO:0007435
The process in which the anatomical structures of the salivary gland are generated and organized.
1 P30371 (/ISA)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 P30371 (/IEP)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 P27090 (/IMP)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 P30371 (/ISA)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 P27090 (/ISO)
Skeletal muscle tissue development GO:0007519
The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
1 P30371 (/TAS)
Female pregnancy GO:0007565
The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.
1 Q07257 (/IEP)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
1 Q07257 (/IEP)
Cell death GO:0008219
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
1 P30371 (/ISA)
Cell death GO:0008219
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
1 P27090 (/ISO)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 P30371 (/ISA)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 P27090 (/ISO)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 Q07257 (/IMP)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 P30371 (/ISA)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 P27090 (/ISO)
Glial cell migration GO:0008347
The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.
1 P30371 (/ISA)
Glial cell migration GO:0008347
The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.
1 P27090 (/ISO)
Gonad development GO:0008406
The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.
1 P30371 (/TAS)
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
1 P30371 (/IEP)
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
1 P27090 (/IMP)
Female gonad development GO:0008585
The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.
1 P30371 (/IEP)
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
1 Q07257 (/IEP)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
1 Q07257 (/IEP)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
1 P30371 (/ISA)
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
1 P30371 (/IDA)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
1 P30371 (/IEP)
Cardioblast differentiation GO:0010002
The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
1 P30371 (/ISA)
Cardioblast differentiation GO:0010002
The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
1 P27090 (/ISO)
Response to organonitrogen compound GO:0010243
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
1 Q07257 (/IEP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P27090 (/IDA)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P27090 (/ISO)
Positive regulation of epithelial cell migration GO:0010634
Any process that activates or increases the frequency, rate or extent of epithelial cell migration.
1 P30371 (/ISA)
Positive regulation of epithelial cell migration GO:0010634
Any process that activates or increases the frequency, rate or extent of epithelial cell migration.
1 P27090 (/ISO)
Negative regulation of alkaline phosphatase activity GO:0010693
Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
1 P30371 (/ISA)
Negative regulation of alkaline phosphatase activity GO:0010693
Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
1 P27090 (/ISO)
Positive regulation of epithelial to mesenchymal transition GO:0010718
Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
1 P30371 (/ISA)
Positive regulation of epithelial to mesenchymal transition GO:0010718
Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
1 P27090 (/ISO)
Negative regulation of macrophage cytokine production GO:0010936
Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
1 P30371 (/ISA)
Negative regulation of macrophage cytokine production GO:0010936
Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
1 P27090 (/ISO)
Positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
1 P30371 (/ISA)
Positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
1 P27090 (/ISO)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
1 P30371 (/ISA)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
1 P27090 (/ISO)
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
1 P27090 (/ISO)
Neural tube development GO:0021915
The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.
1 P30371 (/IEP)
Signal transduction by protein phosphorylation GO:0023014
A process in which the transfer of one or more phosphate groups to a substrate transmits a signal to the phosphorylated substrate.
1 P30371 (/ISA)
Hemopoiesis GO:0030097
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
1 P27090 (/IMP)
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
1 P27090 (/IMP)
Collagen fibril organization GO:0030199
Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.
1 P30371 (/ISA)
Collagen fibril organization GO:0030199
Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.
1 P27090 (/ISO)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
1 P30371 (/ISA)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
1 P27090 (/ISO)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
1 P30371 (/ISA)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
1 P27090 (/ISO)
Lung development GO:0030324
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
1 P30371 (/IEP)
Lung development GO:0030324
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
1 Q07257 (/TAS)
Embryonic limb morphogenesis GO:0030326
The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
1 P27090 (/IMP)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
1 Q07257 (/IDA)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
1 P27090 (/ISO)
Neutrophil chemotaxis GO:0030593
The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
1 P09858 (/IDA)
Thyroid gland development GO:0030878
The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.
1 Q07257 (/IEP)
Hindbrain development GO:0030902
The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).
1 Q07257 (/IEP)
Pancreas development GO:0031016
The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes.
1 Q07257 (/IEP)
Hair follicle morphogenesis GO:0031069
The process in which the anatomical structures of the hair follicle are generated and organized.
1 P27090 (/IMP)
Activation of protein kinase activity GO:0032147
Any process that initiates the activity of an inactive protein kinase.
1 P30371 (/ISA)
Activation of protein kinase activity GO:0032147
Any process that initiates the activity of an inactive protein kinase.
1 P27090 (/ISO)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
1 Q07257 (/IEP)
Response to retinoic acid GO:0032526
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
1 Q07257 (/IEP)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
1 P30371 (/ISA)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
1 P27090 (/ISO)
Positive regulation of stress-activated MAPK cascade GO:0032874
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
1 P30371 (/ISA)
Positive regulation of stress-activated MAPK cascade GO:0032874
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
1 P27090 (/ISO)
Regulation of transforming growth factor beta2 production GO:0032909
Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2.
1 P30371 (/ISA)
Regulation of transforming growth factor beta2 production GO:0032909
Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2.
1 P27090 (/ISO)
Regulation of actin cytoskeleton organization GO:0032956
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
1 P27090 (/IDA)
Response to vitamin D GO:0033280
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
1 Q07257 (/IEP)
Positive regulation of cell adhesion mediated by integrin GO:0033630
Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.
1 P30371 (/ISA)
Positive regulation of cell adhesion mediated by integrin GO:0033630
Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.
1 P27090 (/ISO)
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
1 Q07257 (/IEP)
Response to laminar fluid shear stress GO:0034616
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls.
1 Q07257 (/IEP)
Ascending aorta morphogenesis GO:0035910
The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
1 P27090 (/IMP)
Regulation of growth GO:0040008
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
1 P30371 (/NAS)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
1 Q6T7C3 (/IDA)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
1 Q07257 (/IEP)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
1 Q07257 (/IMP)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
1 P27090 (/ISO)
Endothelial cell activation GO:0042118
The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
1 P30371 (/NAS)
Dopamine biosynthetic process GO:0042416
The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
1 P27090 (/IMP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 Q07257 (/IEP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 P30371 (/ISA)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 P27090 (/ISO)
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
1 P27090 (/IMP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
1 Q07257 (/IMP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
1 P27090 (/ISO)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q07257 (/IDA)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 P27090 (/ISO)
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
1 P30371 (/ISA)
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
1 P27090 (/ISO)
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
1 Q07257 (/IDA)
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
1 P27090 (/ISO)
Cell-cell junction organization GO:0045216
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.
1 P30371 (/ISA)
Cell-cell junction organization GO:0045216
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.
1 P27090 (/ISO)
Regulation of cell differentiation GO:0045595
Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.
1 P30371 (/NAS)
Negative regulation of keratinocyte differentiation GO:0045617
Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation.
1 P27090 (/NAS)
Positive regulation of integrin biosynthetic process GO:0045726
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
1 P30371 (/ISA)
Positive regulation of integrin biosynthetic process GO:0045726
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
1 P27090 (/ISO)
Positive regulation of Notch signaling pathway GO:0045747
Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
1 P27090 (/ISO)
Positive regulation of ossification GO:0045778
Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
1 P30371 (/ISA)
Positive regulation of cell cycle GO:0045787
Any process that activates or increases the rate or extent of progression through the cell cycle.
1 P27090 (/IMP)
Positive regulation of heart contraction GO:0045823
Any process that activates or increases the frequency, rate or extent of heart contraction.
1 P30371 (/ISA)
Positive regulation of heart contraction GO:0045823
Any process that activates or increases the frequency, rate or extent of heart contraction.
1 P27090 (/ISO)
Negative regulation of Ras protein signal transduction GO:0046580
Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
1 P27090 (/IMP)
Somatic stem cell division GO:0048103
The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.
1 P27090 (/IDA)
Animal organ development GO:0048513
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
1 P30371 (/TAS)
Spleen development GO:0048536
The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.
1 P30371 (/IEP)
Digestive tract development GO:0048565
The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.
1 Q07257 (/IEP)
Embryonic digestive tract development GO:0048566
The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus.
1 P30371 (/ISA)
Embryonic organ development GO:0048568
Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
1 P30371 (/IEP)
Neuron fate commitment GO:0048663
The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron.
1 P27090 (/IDA)
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
1 P27090 (/IMP)
Embryonic neurocranium morphogenesis GO:0048702
The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain.
1 Q07257 (/IDA)
Embryonic neurocranium morphogenesis GO:0048702
The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain.
1 P27090 (/ISO)
Inner ear development GO:0048839
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
1 Q07257 (/IEP)
Inner ear development GO:0048839
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
1 P27090 (/IMP)
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
1 P30371 (/ISA)
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
1 P27090 (/ISO)
Positive regulation of protein secretion GO:0050714
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
1 P30371 (/ISA)
Positive regulation of protein secretion GO:0050714
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
1 P27090 (/ISO)
Negative regulation of immune response GO:0050777
Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
1 Q07257 (/IDA)
Negative regulation of immune response GO:0050777
Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
1 P27090 (/ISO)
Positive regulation of immune response GO:0050778
Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
1 P09858 (/IDA)
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
1 P30371 (/TAS)
Negative regulation of release of sequestered calcium ion into cytosol GO:0051280
Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
1 Q07257 (/IDA)
Negative regulation of release of sequestered calcium ion into cytosol GO:0051280
Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
1 P27090 (/ISO)
Regulation of timing of catagen GO:0051794
Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.
1 P27090 (/ISO)
Positive regulation of timing of catagen GO:0051795
Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.
1 P27090 (/ISO)
Positive regulation of cardioblast differentiation GO:0051891
Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
1 P30371 (/ISA)
Positive regulation of cardioblast differentiation GO:0051891
Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
1 P27090 (/ISO)
Cardiac muscle cell proliferation GO:0060038
The expansion of a cardiac muscle cell population by cell division.
1 P30371 (/ISA)
Cardiac muscle cell proliferation GO:0060038
The expansion of a cardiac muscle cell population by cell division.
1 P27090 (/ISO)
Uterus development GO:0060065
The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure.
1 P27090 (/IMP)
Cardiac epithelial to mesenchymal transition GO:0060317
A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
1 P30371 (/ISA)
Cardiac epithelial to mesenchymal transition GO:0060317
A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
1 P27090 (/ISO)
Cardiac epithelial to mesenchymal transition GO:0060317
A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
1 P30371 (/TAS)
Face morphogenesis GO:0060325
The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.
1 P27090 (/IEP)
Frontal suture morphogenesis GO:0060364
The process in which the frontal suture is generated and organized.
1 Q07257 (/IEP)
Pathway-restricted SMAD protein phosphorylation GO:0060389
The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor.
1 P30371 (/ISA)
Pathway-restricted SMAD protein phosphorylation GO:0060389
The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor.
1 P27090 (/ISO)
Regulation of SMAD protein signal transduction GO:0060390
Any process that modulates the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
1 P30371 (/ISA)
SMAD protein signal transduction GO:0060395
The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell.
1 P27090 (/ISO)
Ventricular septum morphogenesis GO:0060412
The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.
1 P27090 (/IMP)
Ventricular septum morphogenesis GO:0060412
The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.
1 P27090 (/TAS)
Atrial septum morphogenesis GO:0060413
The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.
1 P27090 (/IMP)
Response to growth hormone GO:0060416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.
1 P30371 (/IEP)
Negative regulation of cartilage development GO:0061037
Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
1 P27090 (/IMP)
Pharyngeal arch artery morphogenesis GO:0061626
The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery.
1 P27090 (/IMP)
Secondary palate development GO:0062009
The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.
1 P27090 (/IMP)
Positive regulation of activation-induced cell death of T cells GO:0070237
Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells.
1 P27090 (/IDA)
Positive regulation of extracellular matrix disassembly GO:0090091
Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
1 P27090 (/IDA)
Extrinsic apoptotic signaling pathway GO:0097191
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.
1 P30371 (/ISA)
Extrinsic apoptotic signaling pathway GO:0097191
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.
1 P27090 (/ISO)
Positive regulation of protein localization to nucleus GO:1900182
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
1 P27090 (/IDA)
Regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256
Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.
1 P27090 (/IMP)
Positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895
Any process that activates or increases the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.
1 P27090 (/ISO)
Regulation of extracellular matrix organization GO:1903053
Any process that modulates the frequency, rate or extent of extracellular matrix organization.
1 P27090 (/IMP)
Regulation of complement-dependent cytotoxicity GO:1903659
Any process that modulates the frequency, rate or extent of complement-dependent cytotoxicity.
1 P30371 (/ISA)
Substantia propria of cornea development GO:1903701
The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure.
1 P27090 (/IMP)
Positive regulation of GTP binding GO:1904426
Any process that activates or increases the frequency, rate or extent of GTP binding.
1 P27090 (/IDA)
Cranial skeletal system development GO:1904888
The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus.
1 P27090 (/IMP)
Negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation GO:1905006
Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.
1 P27090 (/IMP)
Positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation GO:1905007
Any process that activates or increases the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.
1 P27090 (/IMP)
Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241
Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.
1 P27090 (/IDA)

There are 30 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
148 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(138 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
147 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(137 more)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
145 A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087QXC5 (/ISS) A0A087V5Z8 (/ISS)
(135 more)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
32 P09858 (/ISS) P30371 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS)
(22 more)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
32 P09858 (/ISS) P30371 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS) P61811 (/ISS)
(22 more)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
17 P27090 (/IDA) P30371 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(7 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
14 P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS)
(4 more)
Platelet alpha granule lumen GO:0031093
The volume enclosed by the membrane of the platelet alpha granule.
14 P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS) P61812 (/TAS)
(4 more)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
14 P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA) P61812 (/IDA)
(4 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 P30371 (/ISA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 P27090 (/ISO)
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
1 Q07257 (/IDA)
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
1 P27090 (/ISO)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P27090 (/HDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P30371 (/ISA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P27090 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q07257 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P27090 (/ISO)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
1 P27090 (/IDA)
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
1 Q07257 (/IDA)
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
1 P27090 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q07257 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 P27090 (/ISO)
Secretory granule GO:0030141
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
1 Q07257 (/IDA)
Secretory granule GO:0030141
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
1 P27090 (/ISO)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 P27090 (/IDA)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
1 P30371 (/ISA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 P27090 (/IDA)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
1 P27090 (/ISO)