CATH Superfamily 2.60.120.970
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 12: inhibin beta B chain
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
9 | B6DT33 (/ISS) D2H756 (/ISS) P04088 (/ISS) P17491 (/ISS) P27093 (/ISS) P42917 (/ISS) Q04999 (/ISS) Q589C7 (/ISS) Q9PWG6 (/ISS) |
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
1 | P09529 (/TAS) |
|
Hormone activity GO:0005179
The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
|
1 | P09529 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P09529 (/IPI) |
|
Inhibin binding GO:0034711
Interacting selectively and non-covalently with an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers.
|
1 | P17491 (/IPI) |
|
Inhibin binding GO:0034711
Interacting selectively and non-covalently with an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers.
|
1 | Q04999 (/ISO) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P09529 (/IPI) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q04999 (/ISO) |
|
Host cell surface receptor binding GO:0046789
Interacting selectively and non-covalently with a receptor on the host cell surface.
|
1 | P09529 (/TAS) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
1 | P17491 (/IDA) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
1 | Q04999 (/ISO) |
There are 51 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
|
9 | B6DT33 (/ISS) D2H756 (/ISS) P04088 (/ISS) P09529 (/ISS) P17491 (/ISS) P27093 (/ISS) P42917 (/ISS) Q589C7 (/ISS) Q9PWG6 (/ISS) |
|
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
9 | B6DT33 (/ISS) D2H756 (/ISS) P04088 (/ISS) P17491 (/ISS) P27093 (/ISS) P42917 (/ISS) Q04999 (/ISS) Q589C7 (/ISS) Q9PWG6 (/ISS) |
|
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
9 | B6DT33 (/ISS) D2H756 (/ISS) P04088 (/ISS) P09529 (/ISS) P17491 (/ISS) P27093 (/ISS) P42917 (/ISS) Q589C7 (/ISS) Q9PWG6 (/ISS) |
|
Activin receptor signaling pathway GO:0032924
A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
9 | B6DT33 (/ISS) D2H756 (/ISS) P04088 (/ISS) P17491 (/ISS) P27093 (/ISS) P42917 (/ISS) Q04999 (/ISS) Q589C7 (/ISS) Q9PWG6 (/ISS) |
|
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
|
9 | B6DT33 (/ISS) D2H756 (/ISS) P04088 (/ISS) P09529 (/ISS) P17491 (/ISS) P27093 (/ISS) P42917 (/ISS) Q589C7 (/ISS) Q9PWG6 (/ISS) |
|
Negative regulation of insulin secretion GO:0046676
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin.
|
9 | B6DT33 (/ISS) D2H756 (/ISS) P04088 (/ISS) P09529 (/ISS) P17491 (/ISS) P27093 (/ISS) P42917 (/ISS) Q589C7 (/ISS) Q9PWG6 (/ISS) |
|
Positive regulation of follicle-stimulating hormone secretion GO:0046881
Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
9 | B6DT33 (/ISS) D2H756 (/ISS) P04088 (/ISS) P17491 (/ISS) P27093 (/ISS) P42917 (/ISS) Q04999 (/ISS) Q589C7 (/ISS) Q9PWG6 (/ISS) |
|
Negative regulation of follicle-stimulating hormone secretion GO:0046882
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
9 | B6DT33 (/ISS) D2H756 (/ISS) P04088 (/ISS) P17491 (/ISS) P27093 (/ISS) P42917 (/ISS) Q04999 (/ISS) Q589C7 (/ISS) Q9PWG6 (/ISS) |
|
Negative regulation of hepatocyte growth factor biosynthetic process GO:0048178
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor.
|
9 | B6DT33 (/ISS) D2H756 (/ISS) P04088 (/ISS) P17491 (/ISS) P27093 (/ISS) P42917 (/ISS) Q04999 (/ISS) Q589C7 (/ISS) Q9PWG6 (/ISS) |
|
Positive regulation of ovulation GO:0060279
Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
|
9 | B6DT33 (/ISS) D2H756 (/ISS) P04088 (/ISS) P09529 (/ISS) P17491 (/ISS) P27093 (/ISS) P42917 (/ISS) Q589C7 (/ISS) Q9PWG6 (/ISS) |
|
Embryonic axis specification GO:0000578
The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo.
|
1 | Q91350 (/IMP) |
|
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
|
1 | P09529 (/NAS) |
|
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
|
1 | Q04999 (/TAS) |
|
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
|
1 | P09529 (/TAS) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
1 | P17491 (/IEP) |
|
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
|
1 | P17491 (/IEP) |
|
Female gonad development GO:0008585
The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.
|
1 | P17491 (/IEP) |
|
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
|
1 | Q04999 (/IEP) |
|
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
1 | P09529 (/IEP) |
|
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
1 | P17491 (/IEP) |
|
Response to insecticide GO:0017085
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.
|
1 | P17491 (/IEP) |
|
Pituitary gland development GO:0021983
The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
|
1 | P17491 (/IEP) |
|
Cell differentiation GO:0030154
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
|
1 | P09529 (/NAS) |
|
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
1 | Q04999 (/IEP) |
|
Activin receptor signaling pathway GO:0032924
A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P09529 (/IDA) |
|
Activin receptor signaling pathway GO:0032924
A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q04999 (/ISO) |
|
Response to gonadotropin GO:0034698
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.
|
1 | P17491 (/IEP) |
|
Cellular response to leptin stimulus GO:0044320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism.
|
1 | Q04999 (/IEP) |
|
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
|
1 | Q04999 (/IEP) |
|
Positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743
Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.
|
1 | Q91350 (/IDA) |
|
Negative regulation of insulin secretion GO:0046676
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin.
|
1 | Q04999 (/IMP) |
|
Positive regulation of follicle-stimulating hormone secretion GO:0046881
Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
1 | P09529 (/IPI) |
|
Positive regulation of follicle-stimulating hormone secretion GO:0046881
Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
1 | Q04999 (/ISO) |
|
Negative regulation of follicle-stimulating hormone secretion GO:0046882
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
1 | P09529 (/IPI) |
|
Negative regulation of follicle-stimulating hormone secretion GO:0046882
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
1 | Q04999 (/ISO) |
|
Negative regulation of hepatocyte growth factor biosynthetic process GO:0048178
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor.
|
1 | P09529 (/IDA) |
|
Negative regulation of hepatocyte growth factor biosynthetic process GO:0048178
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor.
|
1 | Q04999 (/ISO) |
|
Oocyte development GO:0048599
The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
|
1 | Q04999 (/IGI) |
|
Positive regulation of ovulation GO:0060279
Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
|
1 | Q04999 (/IMP) |
|
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | P17491 (/IEP) |
|
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
|
1 | P17491 (/IEP) |
|
Cellular response to interleukin-1 GO:0071347
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.
|
1 | P17491 (/IEP) |
|
Cellular response to cholesterol GO:0071397
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.
|
1 | P17491 (/IDA) |
|
Cellular response to cholesterol GO:0071397
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.
|
1 | Q04999 (/ISO) |
|
Cellular response to organic cyclic compound GO:0071407
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
1 | P17491 (/IEP) |
|
Seminiferous tubule development GO:0072520
The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa.
|
1 | P17491 (/IEP) |
|
Cellular response to thyroid hormone stimulus GO:0097067
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.
|
1 | P17491 (/IEP) |
|
Nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry GO:1900164
A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves.
|
1 | P27093 (/TAS) |
|
Cellular response to Thyroglobulin triiodothyronine GO:1904017
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.
|
1 | P17491 (/IEP) |
|
Reproductive senescence GO:1990636
A natural reduction in reproductive capacity with aging, often taking the form of a switch from regular reproductive cycles to irregular and infrequent ones.
|
1 | P17491 (/IEP) |
|
Positive regulation of apoptotic signaling pathway GO:2001235
Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.
|
1 | Q04999 (/IGI) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
9 | B6DT33 (/ISS) D2H756 (/ISS) P04088 (/ISS) P17491 (/ISS) P27093 (/ISS) P42917 (/ISS) Q04999 (/ISS) Q589C7 (/ISS) Q9PWG6 (/ISS) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | P09529 (/TAS) Q04999 (/TAS) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
2 | P09529 (/IDA) Q04999 (/IDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q04999 (/HDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | P17491 (/IDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q04999 (/ISO) |
|
Inhibin B complex GO:0043513
Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-B subunit.
|
1 | P17491 (/IDA) |
|
Inhibin B complex GO:0043513
Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-B subunit.
|
1 | Q04999 (/ISO) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q04999 (/ISO) |
|
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
|
1 | Q04999 (/IDA) |