The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 72: Tripartite motif containing 38

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 B9EKD3 (/IPI) O00635 (/IPI) O00635 (/IPI) Q5SZ99 (/IPI)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of interferon-beta production GO:0032648
Any process that modulates the frequency, rate, or extent of interferon-beta production.
2 B9EKD3 (/IDA) Q5SZ99 (/IDA)
Regulation of interferon-beta production GO:0032648
Any process that modulates the frequency, rate, or extent of interferon-beta production.
2 B9EKD3 (/IMP) Q5SZ99 (/IMP)
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
2 O00635 (/HMP) O00635 (/HMP)
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
2 O00635 (/IDA) O00635 (/IDA)
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
2 B9EKD3 (/ISO) Q5SZ99 (/ISO)
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2 B9EKD3 (/IDA) Q5SZ99 (/IDA)
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2 B9EKD3 (/IMP) Q5SZ99 (/IMP)
Positive regulation of viral genome replication GO:0045070
Any process that activates or increases the frequency, rate or extent of viral genome replication.
2 B9EKD3 (/IDA) Q5SZ99 (/IDA)
Positive regulation of viral genome replication GO:0045070
Any process that activates or increases the frequency, rate or extent of viral genome replication.
2 B9EKD3 (/IMP) Q5SZ99 (/IMP)
Positive regulation of viral entry into host cell GO:0046598
Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell.
2 O00635 (/IDA) O00635 (/IDA)
Positive regulation of viral entry into host cell GO:0046598
Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell.
2 B9EKD3 (/ISO) Q5SZ99 (/ISO)
Negative regulation of defense response to virus GO:0050687
Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.
2 B9EKD3 (/IMP) Q5SZ99 (/IMP)
Positive regulation of DNA-binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
2 O00635 (/IDA) O00635 (/IDA)
Positive regulation of DNA-binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
2 B9EKD3 (/ISO) Q5SZ99 (/ISO)
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
2 O00635 (/IDA) O00635 (/IDA)
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
2 B9EKD3 (/ISO) Q5SZ99 (/ISO)
Interferon-gamma-mediated signaling pathway GO:0060333
A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.
2 O00635 (/TAS) O00635 (/TAS)
Protein K48-linked ubiquitination GO:0070936
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
2 B9EKD3 (/IDA) Q5SZ99 (/IDA)
Protein K48-linked ubiquitination GO:0070936
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
2 B9EKD3 (/IMP) Q5SZ99 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 O00635 (/TAS) O00635 (/TAS)
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