The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 108: Tripartite motif-containing protein 5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
3 | Q5D7H7 (/ISS) Q5D7I1 (/ISS) Q5D7I6 (/ISS) |
|
Signaling pattern recognition receptor activity GO:0008329
Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity.
|
3 | Q5D7H7 (/ISS) Q5D7I1 (/ISS) Q5D7I6 (/ISS) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Activation of innate immune response GO:0002218
Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species.
|
3 | Q5D7H7 (/ISS) Q5D7I1 (/ISS) Q5D7I6 (/ISS) |
|
Regulation of lipopolysaccharide-mediated signaling pathway GO:0031664
Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
|
3 | Q5D7H7 (/ISS) Q5D7I1 (/ISS) Q5D7I6 (/ISS) |
|
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
|
3 | Q5D7H7 (/ISS) Q5D7I1 (/ISS) Q5D7I6 (/ISS) |
|
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
|
3 | Q5D7H7 (/ISS) Q5D7I1 (/ISS) Q5D7I6 (/ISS) |
|
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
|
3 | Q5D7H7 (/ISS) Q5D7I1 (/ISS) Q5D7I6 (/ISS) |
|
Protein K63-linked ubiquitination GO:0070534
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.
|
3 | Q5D7H7 (/ISS) Q5D7I1 (/ISS) Q5D7I6 (/ISS) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
3 | Q5D7H7 (/ISS) Q5D7I1 (/ISS) Q5D7I6 (/ISS) |
