The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
PINIT domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: E3 SUMO-protein ligase gei-17

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
1 Q94361 (/IPI)
SUMO ligase activity GO:0061665
Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S --> X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate.
1 Q94361 (/IDA)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
1 Q94361 (/IMP)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
1 Q94361 (/IGI)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
1 Q94361 (/IMP)
Protein sumoylation GO:0016925
The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.
1 Q94361 (/IDA)
Protein sumoylation GO:0016925
The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.
1 Q94361 (/IMP)
Meiotic metaphase I plate congression GO:0043060
The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis I.
1 Q94361 (/IMP)
Negative regulation of cellular protein catabolic process GO:1903363
Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein catabolic process.
1 Q94361 (/IGI)
Negative regulation of cellular protein catabolic process GO:1903363
Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein catabolic process.
1 Q94361 (/IMP)
Negative regulation of mitotic DNA damage checkpoint GO:1904290
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint.
1 Q94361 (/IGI)
Negative regulation of mitotic DNA damage checkpoint GO:1904290
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint.
1 Q94361 (/IMP)
Positive regulation of error-prone translesion synthesis GO:1904333
Any process that activates or increases the frequency, rate or extent of error-prone translesion synthesis.
1 Q94361 (/IGI)
Positive regulation of error-prone translesion synthesis GO:1904333
Any process that activates or increases the frequency, rate or extent of error-prone translesion synthesis.
1 Q94361 (/IMP)
Protein autosumoylation GO:1990466
The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.
1 Q94361 (/IDA)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
1 Q94361 (/IDA)
Metaphase plate GO:0070090
The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division.
1 Q94361 (/IDA)
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