The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cupin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Putative lysine-specific demethylase 6B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 O15054 (/IPI) Q5NCY0 (/IPI)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 G3V9U4 (/IDA)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 Q5NCY0 (/ISO)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
1 Q5NCY0 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 Q5NCY0 (/IDA)
Histone demethylase activity (H3-K27 specific) GO:0071558
Catalysis of the removal of a methyl group from lysine at position 27 of the histone H3 protein.
1 Q5NCY0 (/IDA)
Histone demethylase activity (H3-K27 specific) GO:0071558
Catalysis of the removal of a methyl group from lysine at position 27 of the histone H3 protein.
1 O15054 (/IMP)
Histone demethylase activity (H3-K27 specific) GO:0071558
Catalysis of the removal of a methyl group from lysine at position 27 of the histone H3 protein.
1 Q5NCY0 (/ISO)

There are 29 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
3 A0A1D5NSI1 (/IGI) E7F6X8 (/IGI) E9QG91 (/IGI)
Heart trabecula morphogenesis GO:0061384
The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.
3 A0A1D5NSI1 (/IGI) E7F6X8 (/IGI) E9QG91 (/IGI)
Histone H3-K27 demethylation GO:0071557
The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone.
2 O15054 (/IMP) Q5NCY0 (/IMP)
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
2 G3V9U4 (/ISS) O15054 (/ISS)
Inflammatory response to antigenic stimulus GO:0002437
An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes.
1 G3V9U4 (/IEP)
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
1 Q5NCY0 (/IMP)
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
1 O15054 (/ISS)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q5NCY0 (/IMP)
Response to activity GO:0014823
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
1 G3V9U4 (/IEP)
Histone demethylation GO:0016577
The modification of histones by removal of methyl groups.
1 Q5NCY0 (/IMP)
Hippocampus development GO:0021766
The progression of the hippocampus over time from its initial formation until its mature state.
1 G3V9U4 (/IDA)
Hippocampus development GO:0021766
The progression of the hippocampus over time from its initial formation until its mature state.
1 Q5NCY0 (/ISO)
Fin regeneration GO:0031101
The regrowth of fin tissue following its loss or destruction.
1 E9QG91 (/IMP)
Cell fate commitment GO:0045165
The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
1 Q5NCY0 (/IMP)
Endothelial cell differentiation GO:0045446
The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
1 Q5NCY0 (/IMP)
Endothelial cell differentiation GO:0045446
The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
1 O15054 (/ISS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q5NCY0 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q5NCY0 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 O15054 (/ISS)
Mesodermal cell differentiation GO:0048333
The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.
1 Q5NCY0 (/IMP)
Mesodermal cell differentiation GO:0048333
The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.
1 O15054 (/ISS)
Cardiac muscle cell differentiation GO:0055007
The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
1 Q5NCY0 (/IMP)
Cardiac muscle cell differentiation GO:0055007
The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
1 O15054 (/ISS)
Primitive erythrocyte differentiation GO:0060319
Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis.
1 E9QG91 (/IMP)
Response to fungicide GO:0060992
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi.
1 G3V9U4 (/IEP)
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
1 Q5NCY0 (/IDA)
Histone H3-K27 demethylation GO:0071557
The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone.
1 Q5NCY0 (/IDA)
Histone H3-K27 demethylation GO:0071557
The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone.
1 Q5NCY0 (/ISO)
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
1 Q5NCY0 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 G3V9U4 (/IDA) Q5NCY0 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q5NCY0 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O15054 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 O15054 (/TAS)
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