The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 20: complement C1q tumor necrosis factor-related prote...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of interleukin-6 production GO:0032755
Any process that activates or increases the frequency, rate, or extent of interleukin-6 production.
4 Q9BXJ3 (/IDA) Q9BXJ3 (/IDA) Q9BXJ3 (/IDA) Q9BXJ3 (/IDA)
Positive regulation of interleukin-6 production GO:0032755
Any process that activates or increases the frequency, rate, or extent of interleukin-6 production.
4 Q8R066 (/ISO) Q8R066 (/ISO) Q8R066 (/ISO) Q8R066 (/ISO)
Positive regulation of interleukin-6-mediated signaling pathway GO:0070105
Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor.
4 Q9BXJ3 (/IDA) Q9BXJ3 (/IDA) Q9BXJ3 (/IDA) Q9BXJ3 (/IDA)
Positive regulation of interleukin-6-mediated signaling pathway GO:0070105
Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor.
4 Q8R066 (/ISO) Q8R066 (/ISO) Q8R066 (/ISO) Q8R066 (/ISO)
Positive regulation of NIK/NF-kappaB signaling GO:1901224
Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.
4 Q9BXJ3 (/IDA) Q9BXJ3 (/IDA) Q9BXJ3 (/IDA) Q9BXJ3 (/IDA)
Positive regulation of NIK/NF-kappaB signaling GO:1901224
Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.
4 Q8R066 (/ISO) Q8R066 (/ISO) Q8R066 (/ISO) Q8R066 (/ISO)
Positive regulation of tumor necrosis factor secretion GO:1904469
Any process that activates or increases the frequency, rate or extent of tumor necrosis factor secretion.
4 Q9BXJ3 (/IDA) Q9BXJ3 (/IDA) Q9BXJ3 (/IDA) Q9BXJ3 (/IDA)
Positive regulation of tumor necrosis factor secretion GO:1904469
Any process that activates or increases the frequency, rate or extent of tumor necrosis factor secretion.
4 Q8R066 (/ISO) Q8R066 (/ISO) Q8R066 (/ISO) Q8R066 (/ISO)
Positive regulation of interleukin-6 secretion GO:2000778
Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion.
4 Q9BXJ3 (/IDA) Q9BXJ3 (/IDA) Q9BXJ3 (/IDA) Q9BXJ3 (/IDA)
Positive regulation of interleukin-6 secretion GO:2000778
Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion.
4 Q8R066 (/ISO) Q8R066 (/ISO) Q8R066 (/ISO) Q8R066 (/ISO)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
4 Q9BXJ3 (/IDA) Q9BXJ3 (/IDA) Q9BXJ3 (/IDA) Q9BXJ3 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
4 Q8R066 (/ISO) Q8R066 (/ISO) Q8R066 (/ISO) Q8R066 (/ISO)
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