The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleoplasmin core domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Nucleoplasmin 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P05221 (/IPI) Q6GQG6 (/IPI) Q86SE8 (/IPI)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 Q80W85 (/IDA)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 Q7M6Z1 (/IDA)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 Q80W85 (/ISO)
Nucleosome binding GO:0031491
Interacting selectively and non-covalently with a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
1 P05221 (/IMP)
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
1 Q86SE8 (/TAS)

There are 29 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
3 A0A2R8QS89 (/IMP) B2CQD3 (/IMP) Q0P4A5 (/IMP)
Blastocyst development GO:0001824
The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.
1 Q86SE8 (/IMP)
Blastocyst development GO:0001824
The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.
1 Q80W85 (/ISO)
Blastocyst development GO:0001824
The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.
1 Q80W85 (/ISS)
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
1 Q86SE8 (/IDA)
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
1 Q80W85 (/IMP)
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
1 Q80W85 (/ISO)
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
1 Q80W85 (/ISS)
Regulation of exit from mitosis GO:0007096
Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.
1 Q86SE8 (/IMP)
Regulation of exit from mitosis GO:0007096
Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.
1 Q80W85 (/ISO)
Regulation of exit from mitosis GO:0007096
Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.
1 Q80W85 (/ISS)
Single fertilization GO:0007338
The union of male and female gametes to form a zygote.
1 Q86SE8 (/IMP)
Single fertilization GO:0007338
The union of male and female gametes to form a zygote.
1 Q80W85 (/ISO)
Single fertilization GO:0007338
The union of male and female gametes to form a zygote.
1 Q80W85 (/ISS)
Oocyte differentiation GO:0009994
The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.
1 Q86SE8 (/IEP)
Oocyte differentiation GO:0009994
The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.
1 Q80W85 (/ISS)
Sperm chromatin decondensation GO:0035041
Unwinding of the condensed nuclear chromatin of an inactive sperm nucleus.
1 P05221 (/IMP)
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
1 Q7M6Z1 (/IDA)
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
1 Q80W85 (/ISO)
Positive regulation of DNA replication GO:0045740
Any process that activates or increases the frequency, rate or extent of DNA replication.
1 Q7M6Z1 (/IDA)
Positive regulation of DNA replication GO:0045740
Any process that activates or increases the frequency, rate or extent of DNA replication.
1 Q80W85 (/ISO)
Positive regulation of meiotic nuclear division GO:0045836
Any process that activates or increases the frequency, rate or extent of meiosis.
1 Q86SE8 (/IMP)
Positive regulation of meiotic nuclear division GO:0045836
Any process that activates or increases the frequency, rate or extent of meiosis.
1 Q80W85 (/ISO)
Positive regulation of meiotic nuclear division GO:0045836
Any process that activates or increases the frequency, rate or extent of meiosis.
1 Q80W85 (/ISS)
Positive regulation of DNA metabolic process GO:0051054
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.
1 Q7M6Z1 (/IDA)
Positive regulation of DNA metabolic process GO:0051054
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.
1 Q80W85 (/ISO)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 Q7M6Z1 (/IDA)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 Q80W85 (/ISO)
Chromosome decondensation GO:0051312
The alteration of chromosome structure from the condensed form to a relaxed disperse form.
1 P05221 (/IMP)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q80W85 (/IDA) Q86SE8 (/IDA)
Cytoplasmic chromatin GO:0000789
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the cytoplasm.
1 Q86SE8 (/IDA)
Cytoplasmic chromatin GO:0000789
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the cytoplasm.
1 Q80W85 (/ISO)
Cytoplasmic chromatin GO:0000789
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the cytoplasm.
1 Q80W85 (/ISS)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
1 Q86SE8 (/IDA)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
1 Q80W85 (/ISO)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
1 Q80W85 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q80W85 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q80W85 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 P05221 (/IDA)
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