The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Galactose-binding domain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Netrin G1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
13 Q8R4F1 (/IPI) Q8R4G0 (/IPI) Q96CW9 (/IPI) Q9Y2I2 (/IPI) Q9Y2I2 (/IPI) Q9Y2I2 (/IPI) Q9Y2I2 (/IPI) Q9Y2I2 (/IPI) Q9Y2I2 (/IPI) Q9Y2I2 (/IPI)
(3 more)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
10 Q9Y2I2 (/IPI) Q9Y2I2 (/IPI) Q9Y2I2 (/IPI) Q9Y2I2 (/IPI) Q9Y2I2 (/IPI) Q9Y2I2 (/IPI) Q9Y2I2 (/IPI) Q9Y2I2 (/IPI) Q9Y2I2 (/IPI) Q9Y2I2 (/IPI)
Cell-cell adhesion mediator activity GO:0098632
The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell.
10 Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
1 Q8R4G0 (/ISO)
Cell-cell adhesion mediator activity GO:0098632
The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell.
1 Q8R4G0 (/ISO)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
11 Q96CW9 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS)
(1 more)
Synaptic membrane adhesion GO:0099560
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
10 Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI) Q9Y2I2 (/IGI)
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
2 Q8R4F1 (/IDA) Q8R4G0 (/IDA)
Modulation of chemical synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
2 Q8R4F1 (/IMP) Q8R4G0 (/IMP)
Synaptic membrane adhesion GO:0099560
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
2 Q8R4F1 (/IDA) Q8R4G0 (/IDA)
Synaptic membrane adhesion GO:0099560
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
2 Q8R4F1 (/IMP) Q8R4G0 (/IMP)
Postsynaptic specialization assembly GO:0098698
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane.
1 Q8R4F1 (/IDA)
Postsynaptic specialization assembly GO:0098698
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane.
1 Q8R4F1 (/IMP)
Synaptic membrane adhesion GO:0099560
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
1 Q8R4G0 (/ISO)
Regulation of presynapse assembly GO:1905606
Any process that modulates the frequency, rate or extent of presynapse assembly.
1 Q8R4F1 (/IDA)
Regulation of presynapse assembly GO:1905606
Any process that modulates the frequency, rate or extent of presynapse assembly.
1 Q8R4F1 (/IMP)

There are 18 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
23 Q8R4F1 (/IDA) Q8R4G0 (/IDA) Q96CW9 (/IDA) Q9Y2I2 (/IDA) Q9Y2I2 (/IDA) Q9Y2I2 (/IDA) Q9Y2I2 (/IDA) Q9Y2I2 (/IDA) Q9Y2I2 (/IDA) Q9Y2I2 (/IDA)
(13 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
11 Q96CW9 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS)
(1 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
11 Q96CW9 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS) Q9Y2I2 (/TAS)
(1 more)
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
11 Q96CW9 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS) Q9Y2I2 (/ISS)
(1 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q8R4F1 (/ISO) Q8R4G0 (/ISO)
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
2 Q8R4F1 (/IDA) Q8R4G0 (/IDA)
Schaffer collateral - CA1 synapse GO:0098685
A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell.
2 Q8R4F1 (/IDA) Q8R4G0 (/IDA)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
2 Q8R4F1 (/IDA) Q8R4G0 (/IDA)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
2 Q8R4F1 (/IMP) Q8R4G0 (/IMP)
Anchored component of presynaptic active zone membrane GO:0099029
The component of the presynaptic active zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
2 Q8R4F1 (/IDA) Q8R4G0 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q96CW9 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8R4F1 (/ISO)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 Q8R4F1 (/IDA)
Intercellular bridge GO:0045171
A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.
1 Q96CW9 (/IDA)
Intercellular bridge GO:0045171
A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.
1 Q8R4F1 (/ISO)
Flemming body GO:0090543
A cell part that is the central region of the midbody characterized by a gap in alpha-tubulin staining. It is a dense structure of antiparallel microtubules from the central spindle in the middle of the intercellular bridge.
1 Q96CW9 (/IDA)
Flemming body GO:0090543
A cell part that is the central region of the midbody characterized by a gap in alpha-tubulin staining. It is a dense structure of antiparallel microtubules from the central spindle in the middle of the intercellular bridge.
1 Q8R4F1 (/ISO)
Schaffer collateral - CA1 synapse GO:0098685
A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell.
1 Q8R4F1 (/IMP)
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