Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.

Any series of molecular signals generated as a consequence of a cell surface pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.

Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an innate immune response.

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.

Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.

Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway.

Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway.

Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.

Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.