The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 170: neurexin-1 isoform X4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 A0A0B4KGL0 (/IPI) A0A0B4KGQ3 (/IPI) A0A0B4KH61 (/IPI) Q3KN41 (/IPI) Q9VCZ9 (/IPI)
Apolipoprotein binding GO:0034185
Interacting selectively and non-covalently with an apolipoprotein, the protein component of a lipoprotein complex.
5 A0A0B4KGL0 (/IPI) A0A0B4KGQ3 (/IPI) A0A0B4KH61 (/IPI) Q3KN41 (/IPI) Q9VCZ9 (/IPI)
Neuroligin family protein binding GO:0097109
Interacting selectively and non-covalently with a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation.
5 A0A0B4KGL0 (/IPI) A0A0B4KGQ3 (/IPI) A0A0B4KH61 (/IPI) Q3KN41 (/IPI) Q9VCZ9 (/IPI)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 Q9VCZ9 (/IPI)
Neurexin family protein binding GO:0042043
Interacting selectively and non-covalently with neurexins, synaptic cell surface proteins related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals.
1 A0A0B4KGL0 (/IPI)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
5 A0A0B4KGL0 (/IDA) A0A0B4KGQ3 (/IDA) A0A0B4KH61 (/IDA) Q3KN41 (/IDA) Q9VCZ9 (/IDA)
Neuromuscular synaptic transmission GO:0007274
The process of synaptic transmission from a neuron to a muscle, across a synapse.
5 A0A0B4KGL0 (/IMP) A0A0B4KGQ3 (/IMP) A0A0B4KH61 (/IMP) Q3KN41 (/IMP) Q9VCZ9 (/IMP)
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
5 A0A0B4KGL0 (/IDA) A0A0B4KGQ3 (/IDA) A0A0B4KH61 (/IDA) Q3KN41 (/IDA) Q9VCZ9 (/IDA)
Associative learning GO:0008306
Learning by associating a stimulus (the cause) with a particular outcome (the effect).
5 A0A0B4KGL0 (/IDA) A0A0B4KGQ3 (/IDA) A0A0B4KH61 (/IDA) Q3KN41 (/IDA) Q9VCZ9 (/IDA)
Regulation of locomotion GO:0040012
Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
5 A0A0B4KGL0 (/IGI) A0A0B4KGQ3 (/IGI) A0A0B4KH61 (/IGI) Q3KN41 (/IGI) Q9VCZ9 (/IGI)
Regulation of locomotion GO:0040012
Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
5 A0A0B4KGL0 (/IMP) A0A0B4KGQ3 (/IMP) A0A0B4KH61 (/IMP) Q3KN41 (/IMP) Q9VCZ9 (/IMP)
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
5 A0A0B4KGL0 (/IDA) A0A0B4KGQ3 (/IDA) A0A0B4KH61 (/IDA) Q3KN41 (/IDA) Q9VCZ9 (/IDA)
Synaptic growth at neuromuscular junction GO:0051124
The growth of a synapse at a neuromuscular junction, the site of apposition of a motor end plate and the subneural cleft of the skeletal muscle fiber that it innervates.
5 A0A0B4KGL0 (/IMP) A0A0B4KGQ3 (/IMP) A0A0B4KH61 (/IMP) Q3KN41 (/IMP) Q9VCZ9 (/IMP)
Vitamin A transport GO:0071938
The directed movement any form of vitamin A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid.
5 A0A0B4KGL0 (/IMP) A0A0B4KGQ3 (/IMP) A0A0B4KH61 (/IMP) Q3KN41 (/IMP) Q9VCZ9 (/IMP)
Regulation of neuromuscular synaptic transmission GO:1900073
Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission.
5 A0A0B4KGL0 (/IGI) A0A0B4KGQ3 (/IGI) A0A0B4KH61 (/IGI) Q3KN41 (/IGI) Q9VCZ9 (/IGI)
Regulation of neuromuscular synaptic transmission GO:1900073
Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission.
5 A0A0B4KGL0 (/IMP) A0A0B4KGQ3 (/IMP) A0A0B4KH61 (/IMP) Q3KN41 (/IMP) Q9VCZ9 (/IMP)
Positive regulation of synaptic vesicle endocytosis GO:1900244
Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis.
5 A0A0B4KGL0 (/IGI) A0A0B4KGQ3 (/IGI) A0A0B4KH61 (/IGI) Q3KN41 (/IGI) Q9VCZ9 (/IGI)
Positive regulation of synaptic vesicle endocytosis GO:1900244
Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis.
5 A0A0B4KGL0 (/IMP) A0A0B4KGQ3 (/IMP) A0A0B4KH61 (/IMP) Q3KN41 (/IMP) Q9VCZ9 (/IMP)
Regulation of terminal button organization GO:2000331
Any process that modulates the frequency, rate or extent of terminal button organization.
5 A0A0B4KGL0 (/IMP) A0A0B4KGQ3 (/IMP) A0A0B4KH61 (/IMP) Q3KN41 (/IMP) Q9VCZ9 (/IMP)
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
2 Q3KN41 (/IMP) Q9VCZ9 (/IMP)
Synaptic vesicle endocytosis GO:0048488
A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms.
2 Q3KN41 (/IMP) Q9VCZ9 (/IMP)
Olfactory learning GO:0008355
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
1 B9VMQ3 (/IMP)
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
1 A0A0B4KGL0 (/IMP)
Terminal button organization GO:0072553
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.
1 Q9VCZ9 (/IMP)
Presynaptic membrane assembly GO:0097105
The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
1 Q9VCZ9 (/IMP)
Neuroligin clustering involved in postsynaptic membrane assembly GO:0097118
The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons.
1 A0A0B4KGL0 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
5 A0A0B4KGL0 (/IDA) A0A0B4KGQ3 (/IDA) A0A0B4KH61 (/IDA) Q3KN41 (/IDA) Q9VCZ9 (/IDA)
Terminal bouton GO:0043195
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
1 A0A0B4KGL0 (/IDA)
Type I terminal bouton GO:0061174
Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
1 Q9VCZ9 (/IDA)
Type I terminal bouton GO:0061174
Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
1 Q3KN41 (/IMP)
Trans-synaptic protein complex GO:0098820
A protein complex that spans the synaptic cleft and has parts in both the pre- and post-synaptic membranes.
1 A0A0B4KGL0 (/IPI)
Integral component of presynaptic membrane GO:0099056
The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 A0A0B4KGL0 (/IDA)