The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Jelly Rolls
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: cAMP-dependent protein kinase type I-alpha regulat...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 21 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
14 P00514 (/IPI) P00514 (/IPI) P00514 (/IPI) P05987 (/IPI) P09456 (/IPI) P10644 (/IPI) P10644 (/IPI) P10644 (/IPI) P10644 (/IPI) P10644 (/IPI)
(4 more)
Protein kinase A catalytic subunit binding GO:0034236
Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A.
12 P00514 (/IPI) P00514 (/IPI) P00514 (/IPI) P05987 (/IPI) P10644 (/IPI) P10644 (/IPI) P10644 (/IPI) P10644 (/IPI) P10644 (/IPI) P10644 (/IPI)
(2 more)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
11 P09456 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P31321 (/IDA) P81377 (/IDA)
(1 more)
CAMP-dependent protein kinase inhibitor activity GO:0004862
Stops, prevents or reduces the activity of a cAMP-dependent protein kinase.
9 P05987 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P31321 (/IDA)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
8 A2R7J4 (/IMP) A2R7J4 (/IMP) P05987 (/IMP) P16905 (/IMP) P16905 (/IMP) P16905 (/IMP) P16905 (/IMP) Q9DBC7 (/IMP)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
8 P09456 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
7 P10644 (/IPI) P10644 (/IPI) P10644 (/IPI) P10644 (/IPI) P10644 (/IPI) P10644 (/IPI) P10644 (/IPI)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
7 P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
6 P12849 (/ISS) P30625 (/ISS) Q7KQK0 (/ISS) Q7KQK0 (/ISS) Q7KQK0 (/ISS) Q7KQK0 (/ISS)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
3 A2R7J4 (/IGI) A2R7J4 (/IGI) Q9DBC7 (/IGI)
CAMP binding GO:0030552
Interacting selectively and non-covalently with cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate).
3 P05987 (/IDA) P09456 (/IDA) P81377 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
3 P00514 (/IPI) P00514 (/IPI) P00514 (/IPI)
CAMP-dependent protein kinase inhibitor activity GO:0004862
Stops, prevents or reduces the activity of a cAMP-dependent protein kinase.
2 P12849 (/ISO) Q9DBC7 (/ISO)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
2 P12849 (/ISO) Q9DBC7 (/ISO)
CAMP binding GO:0030552
Interacting selectively and non-covalently with cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate).
2 P12849 (/ISO) Q9DBC7 (/ISO)
Protein kinase A catalytic subunit binding GO:0034236
Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A.
2 P09456 (/IC) P81377 (/IC)
Protein kinase A catalytic subunit binding GO:0034236
Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A.
2 P12849 (/ISO) Q9DBC7 (/ISO)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
1 P31321 (/NAS)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 Q9DBC7 (/ISO)
CAMP binding GO:0030552
Interacting selectively and non-covalently with cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate).
1 P05987 (/IMP)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
1 Q9DBC7 (/ISO)

There are 63 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Renal water homeostasis GO:0003091
Renal process involved in the maintenance of an internal steady state of water in the body.
8 P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P31321 (/TAS)
Blood coagulation GO:0007596
The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
8 P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P31321 (/TAS)
Activation of protein kinase A activity GO:0034199
Any process that initiates the activity of the inactive enzyme protein kinase A.
8 P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P31321 (/TAS)
Cellular response to glucagon stimulus GO:0071377
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.
8 P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P31321 (/TAS)
Negative regulation of cAMP-dependent protein kinase activity GO:2000480
Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.
8 P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P31321 (/IDA)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
7 P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
7 P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS)
Negative regulation of activated T cell proliferation GO:0046007
Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation.
7 P10644 (/IMP) P10644 (/IMP) P10644 (/IMP) P10644 (/IMP) P10644 (/IMP) P10644 (/IMP) P10644 (/IMP)
Asexual sporulation resulting in formation of a cellular spore GO:0043936
The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
6 A2R7J4 (/IMP) A2R7J4 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP)
Positive regulation of asexual sporulation resulting in formation of a cellular spore GO:0043945
Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.
6 A2R7J4 (/IMP) A2R7J4 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
4 P16905 (/IMP) P16905 (/IMP) P16905 (/IMP) P16905 (/IMP)
Neuromuscular synaptic transmission GO:0007274
The process of synaptic transmission from a neuron to a muscle, across a synapse.
4 P16905 (/IMP) P16905 (/IMP) P16905 (/IMP) P16905 (/IMP)
Ventral cord development GO:0007419
The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms.
4 P16905 (/HMP) P16905 (/HMP) P16905 (/HMP) P16905 (/HMP)
Molting cycle, chitin-based cuticle GO:0007591
The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster.
4 P16905 (/IMP) P16905 (/IMP) P16905 (/IMP) P16905 (/IMP)
Oocyte microtubule cytoskeleton polarization GO:0008103
Establishment and maintenance of a specific axis of polarity of the oocyte microtubule network. The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. An example of this is found in Drosophila melanogaster.
4 P16905 (/IMP) P16905 (/IMP) P16905 (/IMP) P16905 (/IMP)
Olfactory learning GO:0008355
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
4 P16905 (/IMP) P16905 (/IMP) P16905 (/IMP) P16905 (/IMP)
Olfactory learning GO:0008355
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
4 P16905 (/NAS) P16905 (/NAS) P16905 (/NAS) P16905 (/NAS)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
4 Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP)
CAMP-mediated signaling GO:0019933
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell.
4 P16905 (/NAS) P16905 (/NAS) P16905 (/NAS) P16905 (/NAS)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
4 Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
4 Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
4 P16905 (/IDA) P16905 (/IDA) P16905 (/IDA) P16905 (/IDA)
Negative regulation of nuclear division GO:0051784
Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
4 Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP)
Positive regulation of feeding behavior GO:2000253
Any process that activates or increases the frequency, rate or extent of feeding behavior.
4 P16905 (/IGI) P16905 (/IGI) P16905 (/IGI) P16905 (/IGI)
Positive regulation of feeding behavior GO:2000253
Any process that activates or increases the frequency, rate or extent of feeding behavior.
4 P16905 (/IMP) P16905 (/IMP) P16905 (/IMP) P16905 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 P12849 (/TAS) Q9DBC7 (/TAS)
Animal organ morphogenesis GO:0009887
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
2 P12849 (/TAS) Q9DBC7 (/TAS)
Regulation of protein kinase activity GO:0045859
Any process that modulates the frequency, rate or extent of protein kinase activity.
2 P09456 (/IDA) P81377 (/IDA)
Regulation of protein kinase activity GO:0045859
Any process that modulates the frequency, rate or extent of protein kinase activity.
2 P12849 (/ISO) Q9DBC7 (/ISO)
Regulation of meiotic cell cycle process involved in oocyte maturation GO:1903538
Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.
2 F1RV23 (/IMP) P07802 (/IMP)
Negative regulation of cAMP-dependent protein kinase activity GO:2000480
Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.
2 P12849 (/ISO) Q9DBC7 (/ISO)
Activation of MAPK activity GO:0000187
The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
1 P05987 (/IMP)
Mesoderm formation GO:0001707
The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
1 Q9DBC7 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 P31321 (/NAS)
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
1 Q9DBC7 (/IMP)
Female meiotic nuclear division GO:0007143
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.
1 P09456 (/IEP)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 Q9DBC7 (/IMP)
Learning or memory GO:0007611
The acquisition and processing of information and/or the storage and retrieval of this information over time.
1 P12849 (/IMP)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 Q9DBC7 (/TAS)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P05987 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P05987 (/IDA)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P05987 (/IMP)
Regulation of protein kinase A signaling GO:0010738
Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.
1 P05987 (/IMP)
Sporulation resulting in formation of a cellular spore GO:0030435
The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
1 P05987 (/IMP)
Culmination involved in sorocarp development GO:0031154
The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development.
1 P05987 (/IMP)
Regulation of sorocarp development GO:0031156
Any process that modulates the frequency, rate or extent of sorocarp development. An example of this process is found in Dictyostelium discoideum.
1 P05987 (/IMP)
Regulation of sorocarp stalk cell differentiation GO:0031285
Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.
1 P05987 (/IGI)
Sorocarp morphogenesis GO:0031288
The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum.
1 P05987 (/IMP)
Regulation of cAMP-mediated signaling GO:0043949
Any process which modulates the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.
1 P05987 (/IMP)
Sarcomere organization GO:0045214
The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
1 Q9DBC7 (/IMP)
Negative regulation of meiotic nuclear division GO:0045835
Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.
1 P09456 (/IEP)
Regulation of protein kinase activity GO:0045859
Any process that modulates the frequency, rate or extent of protein kinase activity.
1 P05987 (/IMP)
Negative regulation of activated T cell proliferation GO:0046007
Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation.
1 Q9DBC7 (/ISO)
Modulation of chemical synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
1 P12849 (/IMP)
Cardiac muscle cell proliferation GO:0060038
The expansion of a cardiac muscle cell population by cell division.
1 Q9DBC7 (/IMP)
C-di-GMP signaling GO:0061939
Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal.
1 P05987 (/IMP)
Medium-term memory GO:0072375
The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).
1 P30625 (/IMP)
Negative regulation of protein kinase C signaling GO:0090038
Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
1 P30625 (/IGI)
Regulation of synaptic vesicle cycle GO:0098693
Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle.
1 P12849 (/IMP)
Negative regulation of oocyte maturation GO:1900194
Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation.
1 P30625 (/IMP)
Response to curcumin GO:1904643
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus.
1 P05987 (/IMP)
Regulation of establishment of cell polarity GO:2000114
Any process that modulates the frequency, rate or extent of establishment of cell polarity.
1 P30625 (/IGI)
Negative regulation of cAMP-dependent protein kinase activity GO:2000480
Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.
1 P05987 (/IMP)

There are 31 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
12 P00514 (/IDA) P00514 (/IDA) P00514 (/IDA) P09456 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA)
(2 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
9 P05987 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P31321 (/TAS)
Ciliary base GO:0097546
Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area.
8 P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P10644 (/TAS) P31321 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
7 P10644 (/HDA) P10644 (/HDA) P10644 (/HDA) P10644 (/HDA) P10644 (/HDA) P10644 (/HDA) P10644 (/HDA)
Nucleotide-activated protein kinase complex GO:0031588
A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae).
7 P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
7 P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA)
Plasma membrane raft GO:0044853
A membrane raft that is part of the plasma membrane.
7 P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA) P10644 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 P16905 (/HDA) P16905 (/HDA) P16905 (/HDA) P16905 (/HDA)
CAMP-dependent protein kinase complex GO:0005952
An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
4 P05987 (/IDA) P09456 (/IDA) P30625 (/IDA) P81377 (/IDA)
CAMP-dependent protein kinase complex GO:0005952
An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
4 Q7KQK0 (/ISS) Q7KQK0 (/ISS) Q7KQK0 (/ISS) Q7KQK0 (/ISS)
CAMP-dependent protein kinase complex GO:0005952
An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
3 P00514 (/IMP) P00514 (/IMP) P00514 (/IMP)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 F1RV23 (/IMP) P07802 (/IMP)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P12849 (/ISO) Q9DBC7 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P12849 (/TAS) Q9DBC7 (/TAS)
CAMP-dependent protein kinase complex GO:0005952
An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
2 P12849 (/ISO) Q9DBC7 (/ISO)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
2 P12849 (/EXP) Q9DBC7 (/EXP)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
2 P12849 (/IDA) Q9DBC7 (/IDA)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
2 P12849 (/EXP) Q9DBC7 (/EXP)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
2 P12849 (/IDA) Q9DBC7 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
1 P05987 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P30625 (/IDA)
CAMP-dependent protein kinase complex GO:0005952
An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
1 P05987 (/IC)
CAMP-dependent protein kinase complex GO:0005952
An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
1 P31321 (/NAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 P30625 (/IDA)
Nucleotide-activated protein kinase complex GO:0031588
A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae).
1 Q9DBC7 (/ISO)
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
1 Q9DBC7 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q9DBC7 (/ISO)
Plasma membrane raft GO:0044853
A membrane raft that is part of the plasma membrane.
1 Q9DBC7 (/ISO)
Schaffer collateral - CA1 synapse GO:0098685
A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell.
1 P12849 (/IMP)
Hippocampal mossy fiber to CA3 synapse GO:0098686
One of the giant synapses that form between the mossy fiber axons of dentate gyrus granule cells and the large complex spines of CA3 pyramidal cells. It consists of a giant bouton known as the mossy fiber expansion, synapsed to the complex, multiheaded spine (thorny excresence) of a CA3 pyramidal cell.
1 P12849 (/IMP)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
1 P12849 (/IMP)
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