The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Jelly Rolls
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 39: cAMP-dependent protein kinase regulatory subunit

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 P07278 (/IPI) P07278 (/IPI) P07278 (/IPI) P07278 (/IPI) P07278 (/IPI) P07278 (/IPI) P07278 (/IPI) P07278 (/IPI) P36600 (/IPI)
CAMP-dependent protein kinase inhibitor activity GO:0004862
Stops, prevents or reduces the activity of a cAMP-dependent protein kinase.
8 P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA)
CAMP-dependent protein kinase inhibitor activity GO:0004862
Stops, prevents or reduces the activity of a cAMP-dependent protein kinase.
8 P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
8 P07278 (/IPI) P07278 (/IPI) P07278 (/IPI) P07278 (/IPI) P07278 (/IPI) P07278 (/IPI) P07278 (/IPI) P07278 (/IPI)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
3 A2R7J4 (/IMP) A2R7J4 (/IMP) P36600 (/IMP)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
2 Q9HEW1 (/IDA) Q9HEW1 (/IDA)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
2 A2R7J4 (/IGI) A2R7J4 (/IGI)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
1 P36600 (/EXP)
CAMP-dependent protein kinase regulator activity GO:0008603
Modulation of the activity of the enzyme cAMP-dependent protein kinase.
1 P30625 (/ISS)
CAMP binding GO:0030552
Interacting selectively and non-covalently with cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate).
1 P36600 (/IMP)

There are 30 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of cytoplasmic mRNA processing body assembly GO:0010603
Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
8 P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP)
Positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation GO:0036278
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a deprivation of nitrogen.
8 P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP)
Positive regulation of adenylate cyclase activity GO:0045762
Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity.
8 P07278 (/IGI) P07278 (/IGI) P07278 (/IGI) P07278 (/IGI) P07278 (/IGI) P07278 (/IGI) P07278 (/IGI) P07278 (/IGI)
Negative regulation of Ras protein signal transduction GO:0046580
Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
8 P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA)
Negative regulation of Ras protein signal transduction GO:0046580
Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
8 P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP)
Positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation GO:0061406
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of glucose.
8 P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP) P07278 (/IMP)
Protein localization to bud neck GO:0097271
A process in which a protein is transported to, or maintained at, a location within a cellular bud neck.
8 P07278 (/IGI) P07278 (/IGI) P07278 (/IGI) P07278 (/IGI) P07278 (/IGI) P07278 (/IGI) P07278 (/IGI) P07278 (/IGI)
Asexual sporulation resulting in formation of a cellular spore GO:0043936
The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
6 A2R7J4 (/IMP) A2R7J4 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP)
Positive regulation of asexual sporulation resulting in formation of a cellular spore GO:0043945
Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.
6 A2R7J4 (/IMP) A2R7J4 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
4 Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
4 Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
4 Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP)
Negative regulation of nuclear division GO:0051784
Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
4 Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP) Q96UX3 (/IMP)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
2 Q9HEW1 (/IMP) Q9HEW1 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
2 Q9HEW1 (/IMP) Q9HEW1 (/IMP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
2 Q9HEW1 (/IMP) Q9HEW1 (/IMP)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
2 Q9HEW1 (/IMP) Q9HEW1 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
2 Q9HEW1 (/IMP) Q9HEW1 (/IMP)
Negative regulation of filamentous growth of a population of unicellular organisms in response to starvation GO:1900435
Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.
2 Q9HEW1 (/IMP) Q9HEW1 (/IMP)
Negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:1900444
Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.
2 Q9HEW1 (/IMP) Q9HEW1 (/IMP)
CAMP-mediated signaling GO:0019933
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell.
1 P36600 (/IMP)
Cellular response to glucose starvation GO:0042149
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.
1 P36600 (/IDA)
Positive regulation of protein export from nucleus GO:0046827
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.
1 P36600 (/IMP)
Negative regulation of meiotic cell cycle GO:0051447
Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.
1 P36600 (/IGI)
Medium-term memory GO:0072375
The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).
1 P30625 (/IMP)
Negative regulation of protein kinase C signaling GO:0090038
Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
1 P30625 (/IGI)
Negative regulation of oocyte maturation GO:1900194
Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation.
1 P30625 (/IMP)
Regulation of establishment of cell polarity GO:2000114
Any process that modulates the frequency, rate or extent of establishment of cell polarity.
1 P30625 (/IGI)
Negative regulation of cAMP-dependent protein kinase activity GO:2000480
Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.
1 P36600 (/IDA)
Negative regulation of cAMP-dependent protein kinase activity GO:2000480
Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.
1 P36600 (/IMP)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
11 P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P36600 (/IDA) Q9HEW1 (/IDA)
(1 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
9 P07278 (/HDA) P07278 (/HDA) P07278 (/HDA) P07278 (/HDA) P07278 (/HDA) P07278 (/HDA) P07278 (/HDA) P07278 (/HDA) P36600 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P36600 (/IDA)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
8 P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 P07278 (/HDA) P07278 (/HDA) P07278 (/HDA) P07278 (/HDA) P07278 (/HDA) P07278 (/HDA) P07278 (/HDA) P07278 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA) P07278 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9HEW1 (/NAS) Q9HEW1 (/NAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P36600 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P30625 (/IDA)
CAMP-dependent protein kinase complex GO:0005952
An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
1 P30625 (/IDA)
CAMP-dependent protein kinase complex GO:0005952
An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
1 P36600 (/IPI)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 P30625 (/IDA)
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