The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Jelly Rolls
".
FunFam 2: Cyclic nucleotide gated channel alpha 1a
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 21 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Intracellular cGMP-activated cation channel activity GO:0005223
Enables the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts.
|
8 | A0A0G2JVT7 (/IDA) A0A0G2K054 (/IDA) Q00195 (/IDA) Q03611 (/IDA) Q62927 (/IDA) Q9ER32 (/IDA) Q9ER33 (/IDA) Q9QWN7 (/IDA) |
CGMP binding GO:0030553
Interacting selectively and non-covalently with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).
|
7 | A0A0G2JVT7 (/IDA) A0A0G2K054 (/IDA) Q00195 (/IDA) Q62927 (/IDA) Q9ER32 (/IDA) Q9ER33 (/IDA) Q9QWN7 (/IDA) |
CGMP binding GO:0030553
Interacting selectively and non-covalently with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).
|
6 | A0A0G2JVT7 (/NAS) A0A0G2K054 (/NAS) Q03611 (/NAS) Q9ER32 (/NAS) Q9ER33 (/NAS) Q9QWN7 (/NAS) |
Intracellular cGMP-activated cation channel activity GO:0005223
Enables the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts.
|
5 | A0A0G2JVT7 (/NAS) A0A0G2K054 (/NAS) Q9ER32 (/NAS) Q9ER33 (/NAS) Q9QWN7 (/NAS) |
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
5 | A0A0G2JVT7 (/IPI) A0A0G2K054 (/IPI) Q9ER32 (/IPI) Q9ER33 (/IPI) Q9QWN7 (/IPI) |
Intracellular cGMP-activated cation channel activity GO:0005223
Enables the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts.
|
4 | P29974 (/ISO) Q62398 (/ISO) Q62398 (/ISO) Q9JJZ8 (/ISO) |
CGMP binding GO:0030553
Interacting selectively and non-covalently with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).
|
4 | P29974 (/ISO) Q62398 (/ISO) Q62398 (/ISO) Q9JJZ8 (/ISO) |
Intracellular cyclic nucleotide activated cation channel activity GO:0005221
Enables the transmembrane transfer of a cation by a channel that opens when intracellular cyclic nucleotide has been bound by the channel complex or one of its constituent parts.
|
3 | A0A0B4KGC3 (/ISS) Q9W1Z8 (/ISS) Q9W201 (/ISS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | P29973 (/IPI) P29973 (/IPI) Q9JJZ8 (/IPI) |
Ion channel activity GO:0005216
Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
|
2 | Q62398 (/IMP) Q62398 (/IMP) |
Showing 1 to 10 of 21 entries
There are 67 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Response to corticosteroid GO:0031960
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.
|
5 | A0A0G2JVT7 (/IEP) A0A0G2K054 (/IEP) Q9ER32 (/IEP) Q9ER33 (/IEP) Q9QWN7 (/IEP) |
Response to magnesium ion GO:0032026
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.
|
5 | A0A0G2JVT7 (/IDA) A0A0G2K054 (/IDA) Q9ER32 (/IDA) Q9ER33 (/IDA) Q9QWN7 (/IDA) |
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
5 | A0A0G2JVT7 (/IDA) A0A0G2K054 (/IDA) Q9ER32 (/IDA) Q9ER33 (/IDA) Q9QWN7 (/IDA) |
Response to cAMP GO:0051591
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
|
5 | A0A0G2JVT7 (/IDA) A0A0G2K054 (/IDA) Q9ER32 (/IDA) Q9ER33 (/IDA) Q9QWN7 (/IDA) |
Inorganic cation import across plasma membrane GO:0098659
The directed movement of inorganic cations from outside of a cell, across the plasma membrane and into the cytosol.
|
5 | A0A0G2JVT7 (/IDA) A0A0G2K054 (/IDA) Q9ER32 (/IDA) Q9ER33 (/IDA) Q9QWN7 (/IDA) |
Cation transport GO:0006812
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | A0A0B4KGC3 (/ISS) Q9W1Z8 (/ISS) Q9W201 (/ISS) |
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
|
3 | P29973 (/TAS) P29973 (/TAS) Q16281 (/TAS) |
Cyclic-nucleotide-mediated signaling GO:0019935
Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide. Includes production or release of the cyclic nucleotide, and downstream effectors that further transmit the signal within the cell.
|
3 | A0A0B4KGC3 (/ISS) Q9W1Z8 (/ISS) Q9W201 (/ISS) |
Membrane depolarization GO:0051899
The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.
|
3 | P29974 (/ISO) Q62398 (/ISO) Q62398 (/ISO) |
Cation transport GO:0006812
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q00194 (/IMP) Q16281 (/IMP) |
Showing 1 to 10 of 67 entries
There are 37 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
7 | A0A0G2JVT7 (/IDA) A0A0G2K054 (/IDA) Q00195 (/IDA) Q9ER32 (/IDA) Q9ER33 (/IDA) Q9JJZ8 (/IDA) Q9QWN7 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
6 | A0A0G2JVT7 (/IDA) A0A0G2K054 (/IDA) Q62927 (/IDA) Q9ER32 (/IDA) Q9ER33 (/IDA) Q9QWN7 (/IDA) |
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
6 | A0A0G2JVT7 (/IDA) A0A0G2K054 (/IDA) Q03611 (/IDA) Q9ER32 (/IDA) Q9ER33 (/IDA) Q9QWN7 (/IDA) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
6 | A0A0G2JVT7 (/IDA) A0A0G2K054 (/IDA) A8WI01 (/IDA) Q9ER32 (/IDA) Q9ER33 (/IDA) Q9QWN7 (/IDA) |
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
|
6 | A0A0G2JVT7 (/IDA) A0A0G2K054 (/IDA) Q00195 (/IDA) Q9ER32 (/IDA) Q9ER33 (/IDA) Q9QWN7 (/IDA) |
Axon initial segment GO:0043194
Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment.
|
5 | A0A0G2JVT7 (/IDA) A0A0G2K054 (/IDA) Q9ER32 (/IDA) Q9ER33 (/IDA) Q9QWN7 (/IDA) |
Glial cell projection GO:0097386
A prolongation or process extending from a glial cell.
|
5 | A0A0G2JVT7 (/IDA) A0A0G2K054 (/IDA) Q9ER32 (/IDA) Q9ER33 (/IDA) Q9QWN7 (/IDA) |
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
|
3 | P29974 (/IDA) Q9JJZ8 (/IDA) Q9QX26 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | Q62398 (/ISO) Q62398 (/ISO) Q9JJZ8 (/ISO) |
Intracellular cyclic nucleotide activated cation channel complex GO:0017071
A protein complex that forms a transmembrane channel through which cations ions may pass in response to an intracellular cyclic nucleotide binding to the channel complex or one of its constituent parts.
|
3 | Q00195 (/IDA) Q24278 (/IDA) Q62927 (/IDA) |
Showing 1 to 10 of 37 entries