The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Acid Proteases
".
FunFam 66: Napsin A aspartic peptidase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endopeptidase activity GO:0004175
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
|
4 | E1BJW6 (/ISS) F1RH37 (/ISS) G1M3R7 (/ISS) G1R0R7 (/ISS) |
|
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
|
4 | E1BJW6 (/ISS) F1RH37 (/ISS) G1M3R7 (/ISS) G1R0R7 (/ISS) |
|
Endopeptidase activity GO:0004175
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
|
2 | O09043 (/IMP) O09043 (/IMP) |
|
Endopeptidase activity GO:0004175
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
|
2 | O09043 (/ISO) O09043 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O09043 (/IPI) O09043 (/IPI) |
|
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
|
2 | O09043 (/ISO) O09043 (/ISO) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Membrane protein proteolysis GO:0033619
The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.
|
4 | E1BJW6 (/ISS) F1RH37 (/ISS) G1M3R7 (/ISS) G1R0R7 (/ISS) |
|
Surfactant homeostasis GO:0043129
Any process involved in the maintenance of a steady-state level of the surface-active lipoprotein mixture which coats the alveoli.
|
4 | E1BJW6 (/ISS) F1RH37 (/ISS) G1M3R7 (/ISS) G1R0R7 (/ISS) |
|
Membrane protein proteolysis GO:0033619
The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.
|
2 | O09043 (/IMP) O09043 (/IMP) |
|
Membrane protein proteolysis GO:0033619
The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.
|
2 | O09043 (/ISO) O09043 (/ISO) |
|
Surfactant homeostasis GO:0043129
Any process involved in the maintenance of a steady-state level of the surface-active lipoprotein mixture which coats the alveoli.
|
2 | O09043 (/ISO) O09043 (/ISO) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
4 | E1BJW6 (/ISS) F1RH37 (/ISS) G1M3R7 (/ISS) G1R0R7 (/ISS) |
|
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
4 | E1BJW6 (/ISS) F1RH37 (/ISS) G1M3R7 (/ISS) G1R0R7 (/ISS) |
|
Alveolar lamellar body GO:0097208
A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.
|
4 | E1BJW6 (/ISS) F1RH37 (/ISS) G1M3R7 (/ISS) G1R0R7 (/ISS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | O09043 (/ISO) O09043 (/ISO) |
|
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
2 | O09043 (/IDA) O09043 (/IDA) |
|
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
2 | O09043 (/ISO) O09043 (/ISO) |
|
Alveolar lamellar body GO:0097208
A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.
|
2 | O09043 (/IDA) O09043 (/IDA) |
|
Alveolar lamellar body GO:0097208
A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.
|
2 | O09043 (/ISO) O09043 (/ISO) |
