Repression of transcription of telomeric DNA by altering the structure of chromatin.

Repression of transcription at silent mating-type loci by alteration of the structure of chromatin.

Repression of transcription of centromeric DNA by altering the structure of chromatin.

Repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region.

Repression of transcription of ribosomal DNA by altering the structure of chromatin.

Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.

The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.

The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged.

Any process that reduces the extent of heterochromatin formation; reduces the size of a chromosomal region converted to heterochromatin.

The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a mitotic cell cycle.

The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone.

The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone.

Any process that results in the assembly of chromatin into heterochromatin and contributes to chromatin silencing.

Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome.

Nuclear heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3.

The region of a condensed nuclear chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin.

Heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3.

Heterochromatic regions of the chromosome found at silenced mating-type loci.

Heterochromatic regions of the chromosome found at silenced mating-type loci.

The portion of the centromeric region of a chromosome that flanks the core region, encompassing repeated regions of a chromosome centromere and the proteins that bind to it.

A histone deacetylase complex formed by the association of an HP1 protein with a SHREC complex. The SHREC2 complex is required for deacetylation of H3K14, and mediates transcriptional gene silencing by limiting RNA polymerase II access to heterochromatin. In fission yeast, the complex contains the SHREC subunits Clr1, Clr2, Clr3, and Mit1, and the HP1 protein Chp2.

Heterochromatic regions of the chromosome found at the subtelomeric regions of a chromosome in the nucleus.

Heterochromatic regions of the chromosome found at the subtelomeric regions of a chromosome in the nucleus.