CATH Superfamily 2.40.50.40
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 24: C-C motif chemokine 21
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Chemokine activity GO:0008009
The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
|
5 | P84444 (/ISO) P86792 (/ISO) P86792 (/ISO) P86793 (/ISO) P86793 (/ISO) |
Chemokine receptor binding GO:0042379
Interacting selectively and non-covalently with any chemokine receptor.
|
5 | P84444 (/ISO) P86792 (/ISO) P86792 (/ISO) P86793 (/ISO) P86793 (/ISO) |
Chemokine activity GO:0008009
The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
|
4 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) P84444 (/IDA) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | O00585 (/IPI) O00585 (/IPI) O00585 (/IPI) |
Chemokine activity GO:0008009
The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
|
3 | O00585 (/ISS) O00585 (/ISS) O00585 (/ISS) |
CCR7 chemokine receptor binding GO:0031732
Interacting selectively and non-covalently with a CCR7 chemokine receptor.
|
3 | O00585 (/ISS) O00585 (/ISS) O00585 (/ISS) |
Chemokine receptor binding GO:0042379
Interacting selectively and non-covalently with any chemokine receptor.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Chemokine receptor binding GO:0042379
Interacting selectively and non-covalently with any chemokine receptor.
|
2 | Q8HYP5 (/ISS) Q8HYP5 (/ISS) |
Chemokine activity GO:0008009
The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
|
1 | P84444 (/IMP) |
CCR7 chemokine receptor binding GO:0031732
Interacting selectively and non-covalently with a CCR7 chemokine receptor.
|
1 | P84444 (/IPI) |
There are 82 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Dendritic cell chemotaxis GO:0002407
The movement of a dendritic cell in response to an external stimulus.
|
4 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) P84444 (/IDA) |
Establishment of T cell polarity GO:0001768
The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Immunological synapse formation GO:0001771
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
|
3 | O00585 (/ISS) O00585 (/ISS) O00585 (/ISS) |
Positive regulation of cell-matrix adhesion GO:0001954
Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Positive regulation of dendritic cell antigen processing and presentation GO:0002606
Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation.
|
3 | O00585 (/ISS) O00585 (/ISS) O00585 (/ISS) |
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
3 | O00585 (/NAS) O00585 (/NAS) O00585 (/NAS) |
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
3 | O00585 (/TAS) O00585 (/TAS) O00585 (/TAS) |
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
|
3 | O00585 (/TAS) O00585 (/TAS) O00585 (/TAS) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
3 | O00585 (/TAS) O00585 (/TAS) O00585 (/TAS) |
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
|
3 | O00585 (/TAS) O00585 (/TAS) O00585 (/TAS) |
Positive regulation of glycoprotein biosynthetic process GO:0010560
Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
|
3 | O00585 (/ISS) O00585 (/ISS) O00585 (/ISS) |
Positive regulation of T cell chemotaxis GO:0010820
Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.
|
3 | O00585 (/ISS) O00585 (/ISS) O00585 (/ISS) |
Positive regulation of actin filament polymerization GO:0030838
Any process that activates or increases the frequency, rate or extent of actin polymerization.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Positive regulation of pseudopodium assembly GO:0031274
Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
T cell costimulation GO:0031295
The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.
|
3 | O00585 (/ISS) O00585 (/ISS) O00585 (/ISS) |
Ruffle organization GO:0031529
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Positive regulation of cell adhesion mediated by integrin GO:0033630
Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Response to prostaglandin E GO:0034695
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Mesangial cell-matrix adhesion GO:0035759
The binding of a mesangial cell to the extracellular matrix via adhesion molecules. A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Chemokine (C-C motif) ligand 21 signaling pathway GO:0038116
A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
3 | O00585 (/ISS) O00585 (/ISS) O00585 (/ISS) |
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Positive regulation of phosphatidylinositol 3-kinase activity GO:0043552
Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Positive regulation of protein kinase activity GO:0045860
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Positive regulation of JNK cascade GO:0046330
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Positive regulation of receptor-mediated endocytosis GO:0048260
Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
|
3 | O00585 (/ISS) O00585 (/ISS) O00585 (/ISS) |
Cell maturation GO:0048469
A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.
|
3 | O00585 (/ISS) O00585 (/ISS) O00585 (/ISS) |
Positive regulation of chemotaxis GO:0050921
Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
|
3 | O00585 (/ISS) O00585 (/ISS) O00585 (/ISS) |
Release of sequestered calcium ion into cytosol GO:0051209
The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Cell chemotaxis GO:0060326
The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Positive regulation of neutrophil chemotaxis GO:0090023
Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Dendritic cell dendrite assembly GO:0097026
Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.
|
3 | O00585 (/ISS) O00585 (/ISS) O00585 (/ISS) |
Negative regulation of leukocyte tethering or rolling GO:1903237
Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte tethering or rolling.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Cellular response to chemokine GO:1990869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus.
|
3 | O00585 (/ISS) O00585 (/ISS) O00585 (/ISS) |
Positive regulation of cell motility GO:2000147
Any process that activates or increases the frequency, rate or extent of cell motility.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Positive regulation of T cell migration GO:2000406
Any process that activates or increases the frequency, rate or extent of T cell migration.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Positive regulation of myeloid dendritic cell chemotaxis GO:2000529
Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Negative regulation of dendritic cell dendrite assembly GO:2000548
Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly.
|
3 | O00585 (/ISS) O00585 (/ISS) O00585 (/ISS) |
Negative regulation of dendritic cell apoptotic process GO:2000669
Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process.
|
3 | O00585 (/IDA) O00585 (/IDA) O00585 (/IDA) |
Leukocyte chemotaxis GO:0030595
The movement of a leukocyte in response to an external stimulus.
|
2 | P86792 (/ISO) P86792 (/ISO) |
Negative regulation of myeloid cell differentiation GO:0045638
Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
|
2 | P86792 (/ISO) P86792 (/ISO) |
Establishment of T cell polarity GO:0001768
The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.
|
1 | P84444 (/ISS) |
Immunological synapse formation GO:0001771
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
|
1 | P84444 (/IDA) |
Positive regulation of cell-matrix adhesion GO:0001954
Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.
|
1 | P84444 (/ISS) |
Positive regulation of dendritic cell antigen processing and presentation GO:0002606
Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation.
|
1 | P84444 (/IDA) |
Positive regulation of glycoprotein biosynthetic process GO:0010560
Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
|
1 | P84444 (/IDA) |
Positive regulation of macrophage chemotaxis GO:0010759
Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
|
1 | P84444 (/NAS) |
Positive regulation of T cell chemotaxis GO:0010820
Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.
|
1 | P84444 (/IMP) |
Positive regulation of actin filament polymerization GO:0030838
Any process that activates or increases the frequency, rate or extent of actin polymerization.
|
1 | P84444 (/ISS) |
Positive regulation of pseudopodium assembly GO:0031274
Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia.
|
1 | P84444 (/ISS) |
T cell costimulation GO:0031295
The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.
|
1 | P84444 (/IDA) |
Ruffle organization GO:0031529
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell.
|
1 | P84444 (/ISS) |
Positive regulation of cell adhesion mediated by integrin GO:0033630
Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.
|
1 | P84444 (/ISS) |
Response to prostaglandin E GO:0034695
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.
|
1 | P84444 (/ISS) |
Mesangial cell-matrix adhesion GO:0035759
The binding of a mesangial cell to the extracellular matrix via adhesion molecules. A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney.
|
1 | P84444 (/ISS) |
Chemokine (C-C motif) ligand 21 signaling pathway GO:0038116
A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P84444 (/IMP) |
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
|
1 | P84444 (/ISS) |
Positive regulation of phosphatidylinositol 3-kinase activity GO:0043552
Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity.
|
1 | P84444 (/ISS) |
Positive regulation of protein kinase activity GO:0045860
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
|
1 | P84444 (/ISS) |
Positive regulation of JNK cascade GO:0046330
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.
|
1 | P84444 (/ISS) |
Positive regulation of receptor-mediated endocytosis GO:0048260
Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
|
1 | P84444 (/IDA) |
Cell maturation GO:0048469
A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.
|
1 | P84444 (/IDA) |
Lymph node development GO:0048535
The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes.
|
1 | P84444 (/IMP) |
Positive regulation of chemotaxis GO:0050921
Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
|
1 | P84444 (/IDA) |
Induction of positive chemotaxis GO:0050930
Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.
|
1 | P84444 (/IDA) |
Release of sequestered calcium ion into cytosol GO:0051209
The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.
|
1 | P84444 (/ISS) |
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
|
1 | P84444 (/ISS) |
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
1 | P84444 (/ISS) |
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
1 | P84444 (/ISS) |
Positive regulation of neutrophil chemotaxis GO:0090023
Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
1 | P84444 (/ISS) |
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
|
1 | P84444 (/ISS) |
Dendritic cell dendrite assembly GO:0097026
Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.
|
1 | P84444 (/IDA) |
Cellular response to chemokine GO:1990869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus.
|
1 | P84444 (/IMP) |
Positive regulation of cell motility GO:2000147
Any process that activates or increases the frequency, rate or extent of cell motility.
|
1 | P84444 (/ISS) |
Positive regulation of T cell migration GO:2000406
Any process that activates or increases the frequency, rate or extent of T cell migration.
|
1 | P84444 (/ISO) |
Positive regulation of myeloid dendritic cell chemotaxis GO:2000529
Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis.
|
1 | P84444 (/ISS) |
Negative regulation of dendritic cell dendrite assembly GO:2000548
Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly.
|
1 | P84444 (/IDA) |
Negative regulation of dendritic cell apoptotic process GO:2000669
Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process.
|
1 | P84444 (/ISS) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
3 | O00585 (/TAS) O00585 (/TAS) O00585 (/TAS) |
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
2 | P86792 (/IDA) P86792 (/IDA) |