The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Nucleic acid-binding proteins
".
FunFam 495: Single-stranded TG1-3 telomere G-tails binding pro...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P32797 (/IPI) P32797 (/IPI) |
|
Telomerase inhibitor activity GO:0010521
Stops, prevents or reduces the activity of a telomerase. Telomerase catalyzes the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.
|
2 | P32797 (/IDA) P32797 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | P32797 (/IPI) P32797 (/IPI) |
|
Single-stranded telomeric DNA binding GO:0043047
Interacting selectively and non-covalently with single-stranded telomere-associated DNA.
|
2 | P32797 (/IDA) P32797 (/IDA) |
|
Single-stranded telomeric DNA binding GO:0043047
Interacting selectively and non-covalently with single-stranded telomere-associated DNA.
|
2 | P32797 (/IMP) P32797 (/IMP) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Telomere maintenance GO:0000723
Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
|
2 | P32797 (/IMP) P32797 (/IMP) |
|
Telomere maintenance via telomerase GO:0007004
The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.
|
2 | P32797 (/IGI) P32797 (/IGI) |
|
Telomere maintenance via telomerase GO:0007004
The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.
|
2 | P32797 (/IMP) P32797 (/IMP) |
|
Telomere capping GO:0016233
A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins.
|
2 | P32797 (/IMP) P32797 (/IMP) |
|
Regulation of telomere maintenance via telomerase GO:0032210
Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.
|
2 | P32797 (/IDA) P32797 (/IDA) |
|
Regulation of telomere maintenance via telomerase GO:0032210
Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.
|
2 | P32797 (/IGI) P32797 (/IGI) |
|
Negative regulation of telomerase activity GO:0051974
Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
|
2 | P32797 (/IDA) P32797 (/IDA) |
|
Ribonucleoprotein complex localization GO:0071166
Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell.
|
2 | P32797 (/IMP) P32797 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear chromosome, telomeric region GO:0000784
The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
|
2 | P32797 (/IDA) P32797 (/IDA) |
|
CST complex GO:1990879
A complex formed by the association of Cdc13 (CTC1 in mammals) with Stn1 in yeast (OBFC1 in mammals) and Ten1 protein (also TEN1 in mammals) with single-stranded telomeric DNA. The CST complex plays a role in telomere protection.
|
2 | P32797 (/IPI) P32797 (/IPI) |
