The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 439: 23S rRNA (uracil(747)-C(5))-methyltransferase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
TRNA (uracil(54)-C(5))-methyltransferase. [EC: 2.1.1.35]
S-adenosyl-L-methionine + uracil(54) in tRNA = S-adenosyl-L-homocysteine + 5-methyluracil(54) in tRNA.
  • Unlike this enzyme, EC 2.1.1.74 uses 5,10-methylenetetrahydrofolate and FADH(2) to supply the atoms for methylation of U54.
6 I6V1L9 I6V1L9 O58864 Q8U1N4 Q8U1N4 Q9UZR7
23S rRNA (uracil(747)-C(5))-methyltransferase. [EC: 2.1.1.189]
S-adenosyl-L-methionine + uracil(747) in 23S rRNA = S-adenosyl-L- homocysteine + 5-methyluracil(747) in 23S rRNA.
  • The enzyme specifically methylates uracil(747) at C(5) in 23S rRNA.
6 I6UYD3 I6UYD3 O58994 Q8U2K7 Q8U2K7 Q9UZK1
CATH-Gene3D is a Global Biodata Core Resource Learn more...