The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 382: Cold shock protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
6 O65639 (/IDA) Q38896 (/IDA) Q38896 (/IDA) Q41188 (/IDA) Q41188 (/IDA) Q94C69 (/IDA)
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
3 O65639 (/IDA) Q41188 (/IDA) Q41188 (/IDA)
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
3 O65639 (/IDA) Q41188 (/IDA) Q41188 (/IDA)
Nucleic acid binding GO:0003676
Interacting selectively and non-covalently with any nucleic acid.
2 Q41188 (/ISS) Q41188 (/ISS)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 O65639 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q94C69 (/IPI)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
6 O65639 (/IEP) Q38896 (/IEP) Q38896 (/IEP) Q41188 (/IEP) Q41188 (/IEP) Q94C69 (/IEP)
DNA duplex unwinding GO:0032508
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.
4 O65639 (/IDA) Q41188 (/IDA) Q41188 (/IDA) Q94C69 (/IDA)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
3 O65639 (/IEP) Q41188 (/IEP) Q41188 (/IEP)
Cold acclimation GO:0009631
Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.
3 O65639 (/IGI) Q41188 (/IGI) Q41188 (/IGI)
Response to desiccation GO:0009269
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.
2 Q41188 (/IEP) Q41188 (/IEP)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
2 Q41188 (/IEP) Q41188 (/IEP)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
2 Q38896 (/IMP) Q38896 (/IMP)
Fruit development GO:0010154
The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant.
2 Q38896 (/IMP) Q38896 (/IMP)
Vegetative to reproductive phase transition of meristem GO:0010228
The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence.
2 Q41188 (/IMP) Q41188 (/IMP)
Regulation of cellular respiration GO:0043457
Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds.
2 Q41188 (/IMP) Q41188 (/IMP)
Seed development GO:0048316
The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.
2 Q41188 (/IMP) Q41188 (/IMP)
Stamen development GO:0048443
The process whose specific outcome is the progression of the stamen over time, from its formation to the mature structure.
2 Q41188 (/IMP) Q41188 (/IMP)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
1 Q94C69 (/IMP)
Cold acclimation GO:0009631
Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.
1 Q94C69 (/IMP)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
1 O65639 (/IEP)
Unidimensional cell growth GO:0009826
The process in which a cell irreversibly increases in size in one
1 Q94C69 (/IMP)
RNA secondary structure unwinding GO:0010501
The process in which a secondary structure of RNA are broken or 'melted'.
1 O65639 (/IDA)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 Q38896 (/IDA) Q38896 (/IDA) Q41188 (/IDA) Q41188 (/IDA) Q94C69 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 Q38896 (/IDA) Q38896 (/IDA) Q41188 (/IDA) Q41188 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q41188 (/IDA) Q41188 (/IDA) Q94C69 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
2 Q41188 (/IDA) Q41188 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q41188 (/IDA) Q41188 (/IDA)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
2 Q41188 (/IDA) Q41188 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O65639 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O65639 (/ISS)
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