The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 307: Eukaryotic translation initiation factor 5A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
4 Q387H6 (/ISM) Q387H6 (/ISM) Q387H6 (/ISM) Q387H6 (/ISM)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
4 Q387H6 (/ISM) Q387H6 (/ISM) Q387H6 (/ISM) Q387H6 (/ISM)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
4 Q387H6 (/IMP) Q387H6 (/IMP) Q387H6 (/IMP) Q387H6 (/IMP)
Peptidyl-lysine modification to peptidyl-hypusine GO:0008612
The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
4 A4GVE9 (/IDA) A4GVE9 (/IDA) A4GVE9 (/IDA) A4GVE9 (/IDA)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
4 Q387H6 (/IMP) Q387H6 (/IMP) Q387H6 (/IMP) Q387H6 (/IMP)
Positive regulation of cytokinesis GO:0032467
Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.
4 Q387H6 (/IMP) Q387H6 (/IMP) Q387H6 (/IMP) Q387H6 (/IMP)
Regulation of cell projection assembly GO:0060491
Any process that modulates the rate, frequency, or extent of cell projection assembly.
4 Q387H6 (/IMP) Q387H6 (/IMP) Q387H6 (/IMP) Q387H6 (/IMP)
Positive regulation of cell aging GO:0090343
Any process that increases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.
4 Q387H6 (/IMP) Q387H6 (/IMP) Q387H6 (/IMP) Q387H6 (/IMP)
Peptidyl-lysine modification to peptidyl-hypusine GO:0008612
The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
1 E9AXF0 (/ISS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q387H6 (/IDA) Q387H6 (/IDA) Q387H6 (/IDA) Q387H6 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q387H6 (/ISA) Q387H6 (/ISA) Q387H6 (/ISA) Q387H6 (/ISA)
Polysome GO:0005844
A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
4 Q387H6 (/ISO) Q387H6 (/ISO) Q387H6 (/ISO) Q387H6 (/ISO)
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