The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: 50S ribosomal protein L2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
220 P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA)
(210 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
219 P60422 (/IPI) P60422 (/IPI) P60422 (/IPI) P60422 (/IPI) P60422 (/IPI) P60422 (/IPI) P60422 (/IPI) P60422 (/IPI) P60422 (/IPI) P60422 (/IPI)
(209 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
219 P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA)
(209 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
22 Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS)
(12 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribosomal large subunit assembly GO:0000027
The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.
219 P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA)
(209 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
22 Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS)
(12 more)
Ribosome biogenesis GO:0042254
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
7 Q5HS93 (/ISS) Q5HS93 (/ISS) Q5HS93 (/ISS) Q5HS93 (/ISS) Q5HS93 (/ISS) Q5HS93 (/ISS) Q5HS93 (/ISS)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
1 Q9AMK8 (/IDA)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
219 P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA)
(209 more)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
219 P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA) P60422 (/IDA)
(209 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
13 P9WHA5 (/HDA) P9WHA5 (/HDA) P9WHA5 (/HDA) P9WHA5 (/HDA) P9WHA5 (/HDA) P9WHA5 (/HDA) P9WHA5 (/HDA) P9WHA5 (/HDA) P9WHA5 (/HDA) P9WHA5 (/HDA)
(3 more)
Large ribosomal subunit GO:0015934
The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site).
11 Q9L0D7 (/ISS) Q9L0D7 (/ISS) Q9L0D7 (/ISS) Q9L0D7 (/ISS) Q9L0D7 (/ISS) Q9L0D7 (/ISS) Q9L0D7 (/ISS) Q9L0D7 (/ISS) Q9L0D7 (/ISS) Q9L0D7 (/ISS)
(1 more)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
11 Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS) Q9KNY7 (/ISS)
(1 more)
Large ribosomal subunit GO:0015934
The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site).
1 Q9AMK8 (/IDA)
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