The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 251: MP18 RNA editing complex protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
4 D6XMN0 (/IDA) D6XMN0 (/IDA) Q95W13 (/IDA) Q95W13 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
4 Q38B90 (/IDA) Q38B90 (/IDA) Q38B90 (/IDA) Q95W12 (/IDA)
Endonuclease activity GO:0004519
Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
4 Q38B90 (/IDA) Q38B90 (/IDA) Q38B90 (/IDA) Q95W12 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
4 D6XMN0 (/IDA) D6XMN0 (/IDA) Q95W13 (/IDA) Q95W13 (/IDA)
Endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891
Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
4 D6XMN0 (/IDA) D6XMN0 (/IDA) Q95W13 (/IDA) Q95W13 (/IDA)
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
1 Q4QIH9 (/ISO)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q6T456 (/ISO)
Endonuclease activity GO:0004519
Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
1 Q6T456 (/ISO)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 Q4QIH9 (/ISO)
Endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891
Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
1 Q4QIH9 (/ISO)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA modification GO:0009451
The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
5 Q38B90 (/TAS) Q38B90 (/TAS) Q38B90 (/TAS) Q6T456 (/TAS) Q95W12 (/TAS)
Response to metal ion GO:0010038
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
4 D6XMN0 (/IDA) D6XMN0 (/IDA) Q95W13 (/IDA) Q95W13 (/IDA)
MRNA modification GO:0016556
The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
4 D6XMN0 (/IDA) D6XMN0 (/IDA) Q95W13 (/IDA) Q95W13 (/IDA)
Response to metal ion GO:0010038
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
1 Q4QIH9 (/ISO)
MRNA modification GO:0016556
The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
1 Q4QIH9 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
8 D6XMN0 (/RCA) D6XMN0 (/RCA) Q38B90 (/RCA) Q38B90 (/RCA) Q38B90 (/RCA) Q95W12 (/RCA) Q95W13 (/RCA) Q95W13 (/RCA)
Kinetoplast GO:0020023
A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.
8 D6XMN0 (/IDA) D6XMN0 (/IDA) Q38B90 (/IDA) Q38B90 (/IDA) Q38B90 (/IDA) Q95W12 (/IDA) Q95W13 (/IDA) Q95W13 (/IDA)
Mitochondrial mRNA editing complex GO:0031019
An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.
8 D6XMN0 (/RCA) D6XMN0 (/RCA) Q38B90 (/RCA) Q38B90 (/RCA) Q38B90 (/RCA) Q95W12 (/RCA) Q95W13 (/RCA) Q95W13 (/RCA)
Mitochondrial mRNA editing complex GO:0031019
An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.
5 Q38B90 (/IDA) Q38B90 (/IDA) Q38B90 (/IDA) Q6T456 (/IDA) Q95W12 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q38B90 (/IDA) Q38B90 (/IDA) Q38B90 (/IDA) Q95W12 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 D6XMN0 (/IDA) D6XMN0 (/IDA) Q95W13 (/IDA) Q95W13 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q4QIH9 (/ISO)
Mitochondrial mRNA editing complex GO:0031019
An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.
1 Q4QIH9 (/ISO)
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