The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Nucleic acid-binding proteins
".
FunFam 134: ATP-dependent DNA helicase RecG
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
DNA helicase activity GO:0003678
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
|
23 |
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
(13 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
23 |
P24230 (/IPI)
P24230 (/IPI)
P24230 (/IPI)
P24230 (/IPI)
P24230 (/IPI)
P24230 (/IPI)
P24230 (/IPI)
P24230 (/IPI)
P24230 (/IPI)
P24230 (/IPI)
(13 more) |
DNA helicase activity GO:0003678
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
|
7 | Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) |
Four-way junction helicase activity GO:0009378
Catalysis of the reaction: ATP + H2O = ADP + phosphate, where this reaction drives the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions.
|
7 | Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
|
23 |
P24230 (/IMP)
P24230 (/IMP)
P24230 (/IMP)
P24230 (/IMP)
P24230 (/IMP)
P24230 (/IMP)
P24230 (/IMP)
P24230 (/IMP)
P24230 (/IMP)
P24230 (/IMP)
(13 more) |
DNA duplex unwinding GO:0032508
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.
|
23 |
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
(13 more) |
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
|
7 | Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) |
DNA recombination GO:0006310
Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
|
7 | Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
23 |
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
(13 more) |
Holliday junction helicase complex GO:0009379
A DNA helicase complex found at Holliday junctions where the helicase activity is involved in the migration of the junction branch point. The best-characterized example is the E. coli RuvAB complex, in which a hexamer of RuvB subunits possesses helicase activity that is modulated by association with RuvA.
|
23 |
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
P24230 (/IDA)
(13 more) |